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Doctor insights on: Tizanidine Liver

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Prescribed zanaflex for spasm. Haven't slept well all week. Doc said would knock me out. Wide awake. I have pbc of liver. I thought soma pref?

Prescribed zanaflex for spasm. Haven't slept well all week. Doc said would knock me out. Wide awake. I have pbc of liver. I thought soma pref?

Soma not preferred: Soma is not a good medication, there are terrible problems with addiction to that drug. Flexeril is another alternative for spasm. Also make sure you are well hydrated and add a multivitamin/multimineral supplement daily. Stretching, warm soaks and daily exercise can also help prevent spasms. ...Read more

Dr. Debra Rosenblatt
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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1.Will high doses of tizanidine harm kidneys? If so, why and how? 2. Can generic brands of meds not work as well or even not at all? Thank you!

1.Will high doses of tizanidine harm kidneys? If so, why and how? 2. Can generic brands of meds not work as well or even not at all? Thank you!

More likely liver: Tizanidine more likely will cause damage to your liver due to the metabolism of the drug but its about 60 % excreted through the kidneys, so it's possible that it could cause some damage at very high doses, but it normally damages liver. Ibuprofen is more likely causing kidney issues. Generic brands normally work exactly the same as long as they are from reputable companies. Hope this helps! ...Read more

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Severe insomnia, depression. Taking zonisamide, tizanidine, ambien. Averaging 2 hrs sleep. Zyprexa just added, weight gain concern! syroquel prev added 80lbs w/strict diet, exercise. Likely w/zyprexa?

Severe insomnia, depression. Taking zonisamide, tizanidine, ambien. Averaging 2 hrs sleep. Zyprexa just added, weight gain concern! syroquel prev added 80lbs w/strict diet, exercise. Likely w/zyprexa?

Need diagnosis: Have a sleep study to ascertain the correct diagnosis and thus the correct treatment. Mood disorders[depression] is made more difficult to treat when there is an underlying sleep disorder.. We are always on shaky ground when we treat symptoms without having the diagnosis established. ...Read more

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Please describe the medication: tizanidine?

Please describe the medication: tizanidine?

Zanaflex: Is a drug that is used as a muscle relaxant. It is a centrally acting ?2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. ...Read more

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I took four times my dose of tizanidine because it wasn't helping enoug, but will I overdose?

I took four times my dose of tizanidine because it wasn't helping enoug, but will I overdose?

TIZANIDINE HAS A: Broad spectrum and it is unlikely you will overdose unless you go above 24 mgs in a 24 hr period. ...Read more

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Can I take lisnopril 10mg with Tizanidine 4 mg?

Can I take lisnopril 10mg with Tizanidine 4 mg?

Well: If your blood pressure is on the high side, then tizanidine might be OK to take. If your blood pressure is well controlled or low with the lisinopril, you may want to try another muscle relaxant as it is known to cause orthostatic hypotension. Talk with your doctor who prescribed it if you are concerned. ...Read more

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Will tizanidine help control or reduce dystonia?

Will tizanidine help control or reduce dystonia?

Sometimes: Zaneflex is indicated for muscle spasticity due to MS or spinal cord injuries. It has been found to help with dystonias (20%). The most commonly used muscle relaxant is baclofen. Side effects include sedation, infrequent tolerance, and dysphoria - depressive mood. ...Read more

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Is tizanidine addictive?

No: But like all medications, take with medical supervision, and follow the instructions on the bottle. ...Read more

Dr. Barbara Lavi
126 doctors shared insights

Tizanidine (Definition)

Is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine ...Read more


Dr. Tipu Sultan
116 doctors shared insights

Zanaflex (Definition)

Zanaflex is a muscle relaxant which is a ...Read more