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Doctor insights on: Tizanidine Interactions

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I take Zanaflex (tizanidine) or flexeril (have both) and just started necon 10/11. I read there could be interactions with zanaflex (tizanidine). Do i need to be concerned?

I take Zanaflex (tizanidine)  or flexeril (have both) and just started necon 10/11. I read there could be interactions with zanaflex (tizanidine). Do i need to be concerned?

Yes- Sedation/dizzy: If you use Zanaflex (tizanidine) chronically, know that the concentration of Zanaflex is increased when used with oral contraceptive and may result in increased sedation, fatigue/ low blood pressure (hypotensive issues- dizziness, fainting). You may want to use Flexeril (cyclobenzaprine hcl) instead but also watch out for drowsiness, fatigue, dizziness. Avoid alcohol and use caution when driving while on these drugs. ...Read more

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Dr. James Chapman
141 doctors shared insights

Tizanidine (Definition)

Is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine ...Read more


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I take Gabapentin 900mg per day, Tizanidine 4mg as needed, Levothyroxine 75mcg, Nitrofurantoin temp) and Adipex-P. Interactions?

I take Gabapentin 900mg per day,  Tizanidine 4mg as needed,  Levothyroxine 75mcg, Nitrofurantoin temp) and Adipex-P. Interactions?

No interactions: there is no interaction between these meds. Please always check with your physician if you have health questions or concerns. ...Read more

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Please describe the medication: tizanidine?

Please describe the medication: tizanidine?

Zanaflex (tizanidine): Is a drug that is used as a muscle relaxant. It is a centrally acting ?2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. ...Read more

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Can i take lithium and Zanaflex (tizanidine) together?

Can i take lithium and Zanaflex (tizanidine) together?

Caution warranted: Hopefully the same physician is prescribing all your medications, or at least knows all you're taking. Zanaflex (tizanidine) is a muscle relaxer that can cause drowsiness. This could be accentuated if you're on lithium. However, i see you're also on klonopin, which is more likely to cause sedation than lithium. Please discuss all these with your doctor and your pharmacist. ...Read more

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What are some of the dangers of zanaflex (tizanidine)?

What are some of the dangers of zanaflex (tizanidine)?

Allergic reactions: Zanaflex (tizanidine) commonly causes dry mouth and constipation, but in some people there are some dangerous potential effects, many of which are allergies (rash, hives, itching, and swollen airways causing breathing difficulties). Other dangers include potential liver damage and psychological effects such as hallucinations. If you have any side effect from any medication inform your doctor. ...Read more

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Hello what could happen if someone takes 7 4mg tizanidine?

It could kill you!: It is very dangerous to take that much of the drug. It can put you in a coma, stop your breathing and as a result kill you. Get help. ...Read more

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How long does it take for Zanaflex (tizanidine) to leave the body?

How long does it take for Zanaflex (tizanidine) to leave the body?

It takes...: 36 hours to get to 1% of your original levels, at which point it would be a non-issue! ...Read more

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I took four times my dose of tizanidine because it wasn't helping enoug, but will I overdose?

I took four times my dose of tizanidine because it wasn't helping enoug, but will I overdose?

TIZANIDINE HAS A: Broad spectrum and it is unlikely you will overdose unless you go above 24 mgs in a 24 hr period. ...Read more

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I reached goal dose of zanaflex (tizanidine) may 18, but had some improvement in last couple days. Is this meds taking full effect or are my symptoms improving?

Hard to know: Firstly, good for you! The question might be possible to answer, but it requires sifting through all sorts of things - like what might be different in your life - what you are doing differently inside and out. You might want to find a good therapist to help you understand it all before you taper down. Never just stop w/o guidance. Happy for you! ...Read more

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Is tizanidine addictive?

No: But like all medications, take with medical supervision, and follow the instructions on the bottle. ...Read more

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Is tizanidine an opiate?

Is tizanidine an opiate?

No: "Mechanism of action. Tizanidine is a central alpha-2-adrenergic receptor agonist and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. The effects of tizanidine are greatest on polysynaptic pathways." That is not an narcotic/opiate ...Read more

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Can I mix tea and tizanidine (zanaflex)?

Of course: There is no problem to mix tea and Zanaflex (tizanidine). ...Read more

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What are the side effects of tizanidine?

What are the side effects of tizanidine?

MANY mainly sedation: Any medication can cause a rash. But since tizanidine (zanaflex) is a 'muscle relaxer' it can cause sedation. It can also cause: dizziness, nervousness, depression vomiting, tingling sensation in the arms, legs, hands, and feet dry mouth, constipation, diarrhea, stomach pain, heartburn, increased muscle spasms and sweating. Tizanidine is used to relieve the spasms due to multiple sclerosis (ms). ...Read more

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Does zanaflex (tizanidine) work for anxiety?

Does zanaflex (tizanidine) work for anxiety?

NO: NO IT IS A MUSCLE RELAXANT. now if the patient anxiety coming from the pain associated with the muscle spasm then yes it mught work that way. ...Read more

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Dr. Tipu Sultan
132 doctors shared insights

Zanaflex (Definition)

Zanaflex is a muscle relaxant which is a ...Read more