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Doctor insights on: Tizanidine Insomnia

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Severe insomnia, depression. Taking zonisamide, tizanidine, ambien (zolpidem). Averaging 2 hrs sleep. Zyprexa just added, weight gain concern! syroquel prev added 80lbs w/strict diet, exercise. Likely w/zyprexa?

Severe insomnia, depression. Taking zonisamide, tizanidine, ambien (zolpidem). Averaging 2 hrs sleep. Zyprexa just added, weight gain concern! syroquel prev added 80lbs w/strict diet, exercise. Likely w/zyprexa?

Need diagnosis: Have a sleep study to ascertain the correct diagnosis and thus the correct treatment. Mood disorders[depression] is made more difficult to treat when there is an underlying sleep disorder.. We are always on shaky ground when we treat symptoms without having the diagnosis established. ...Read more

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Dr. Heidi Fowler
1,703 doctors shared insights

Insomnia (Definition)

A sleep disorder in which you cannot fall or stay asleep. It usually accompanies another sleep, medical, or psychiatric disorder, and can lead to memory impairment, mood changes, and increased risk of ...Read more


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Please describe the medication: tizanidine?

Please describe the medication: tizanidine?

Muscle relaxant: A muscle relaxant to help relax spastic muscles. Can help with pain caused by contracting muscles or spastic muscles. ...Read more

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Is tizanidine addictive?

No: But like all medications, take with medical supervision, and follow the instructions on the bottle. ...Read more

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Is tizanidine an opiate?

Is tizanidine an opiate?

No: "Mechanism of action. Tizanidine is a central alpha-2-adrenergic receptor agonist and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. The effects of tizanidine are greatest on polysynaptic pathways."
That is not an narcotic/opiate ...Read more

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Is Zanaflex (tizanidine) stronger than Flexeril?

Is Zanaflex (tizanidine) stronger than Flexeril?

Zanaflex (tizanidine) & Flexeril: there is no such thing as "best", "worst" or "stronger" medication, only those that work and don't work, based on the patient's individual circumstances and genetics. ...Read more

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How effective is tizanidine for relaxing muscles?

Response varies: Tizanidine is one of the drugs used to treat spasticity. It's effectiveness vary from person to person. Start at a dose of 2 mg and this could be tapered up to 4 mg. Bear in mind that the med could drop your blood pressure. Also, LFT's have to be monitored at least once every 3 months. Other drugs used for spasticity are: baclofen and dantrolene. Relaxants: skelaxin, (metaxalone) flexeril, norflex.. ...Read more

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Are blood thinning properties found in tizanidine?

Are blood thinning properties found in tizanidine?

No: There are some blod dyscrasias but no known blood thinng properties. But if you are having a problem be sure there is no a drug interaction that tizanidine could be cusing another drugs to exhibit blood thinning effcts. ...Read more

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How is Zanaflex (tizanidine) different than flexeril?

How is Zanaflex (tizanidine) different than flexeril?

Zanaflex (tizanidine) vs.Flexeril: Flexeril differs from the other centrally acting agents because it is structurally and pharmacologically related to amitriptyline, a tricyclic antidepressant. Zanaflex (tizanidine) is an alpha adrenergic agonist that inhibits the release of NE from the locus ceruleus in the brain. ...Read more

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Dr. Paul Grin Dr. Grin
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Can I take percocet and Zanaflex (tizanidine) together?

Dr. Paul Grin Dr. Grin
2 doctors agreed:

Yes, you can: There is no interactions between these 2 drugs. ...Read more

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Can i take Zanaflex (tizanidine) and trazodone together?

Sleep: The combination of Zanaflex (tizanidine) and trazadone may lead to a difficulty during the night and next day. Both are sedating medications but the combination may lead to excessive sedation the following day. ...Read more

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Can Zanaflex (tizanidine) and vicodin be taken together?

Probably not. : Both medications have sedative effects and decreased gargle reflex, and cause depressed feeling. If you take together, you have more chance to suffer from side effects, such as being choked, developing aspiration etc. ...Read more

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Could tizanidine and nuberol forte be given simultaneously?

Yes,: There is no interactions between these drugs.
Rec.: if concerned see your prescribing physician for medication adjustment and more information. ...Read more

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Can you take Zanaflex (tizanidine) and hydrocodone together?

Yes: They are often prescribed for concomitant use. Do watch for the side effects of sedation which both may cause in some people. ...Read more

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Can you take hydrocodone and Zanaflex (tizanidine) together?

Yes : The drugs are often prescribed for concomitant use. As both can cause some sedation, be careful with the combination until you see how you respond. ...Read more

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Can tizanidine and nuberol forte be given out simultaneously?

Yes, no problems: there is no drug interaction between these medications. However, always talk with your physician to make sure you can use certain medication safely. Take care. ...Read more

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Will Zanaflex (tizanidine) cause you to fail a urine drug test?

Will Zanaflex (tizanidine) cause you to fail a urine drug test?

No.: Urine drug testing using modern gas chromatography and mass spectroscopy for confirmatory chemical analysis will not mistake tizanidine (zanaflex) for another substance. ...Read more

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Can zanaflex (tizanidine) and vistaril be taken in the same day?

Can zanaflex (tizanidine) and vistaril be taken in the same day?

Shouldn't : There is interaction that combination can have cumulative effect of CNS depression and psychomotor depression. If you need these on a regular basis you need to find the cause. Please visit us www.ehacstl.com to learn how we propose to treat the causeĀ for allergy and related problems ...Read more

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Can zanaflex (tizanidine) and vistaril be taken on the same day?

Can zanaflex (tizanidine) and vistaril be taken on the same day?

Yes: Xanaflex may have some mild sedating effect which may add to to sedating effect of Vistaril (hydroxyzine). Do note that the FDA has issued warning on the potential cardiovascular effect from Vistaril (hydroxyzine). It is not as safe as we once thought. ...Read more

Dr. Julie Abbott
142 doctors shared insights

Tizanidine (Definition)

A muscle relaxant to help relax spastic muscles. Can help with pain caused by contracting ...Read more


Dr. Alex Mompoint
134 doctors shared insights

Zanaflex (Definition)

Zanaflex is a muscle relaxant which is a ...Read more