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Tissue Plasminogen Activator
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
Clot Buster: Tissue plasminogen activator (tpa) is a chemical that triggers rapid breakdown of blood clots. It is used in stroke patients in an attempt to restore bloodflow to the brain before cells die, but the risk of bleeding makes it safe to use only in very specific circumstances. The most common reason for not qualifying for tpa is not getting to the er quickly enough- don't wait! time is brain! ...Read more
Got superficial blood clots in left arm with no cause again. Coagulation panel showed high plasminogen. What does that mean?
Too much plasminogen: Your high plasminogen likely causes, or is related to, your clotting problem. See an explanation of your rare disorder on this website (cut and paste into web browser): http://www.chla.org/site/c.ipINKTOAJsG/b.7717791/k.A1D0/Disorders_of_Fibrinolysis__Bleeding_Disorder__Plasminogen.htm#.VAhd29m9LCQ Talk to a hematologist for more understanding. Best wishes! ...Read more
What do you think of optimal chiropractic treatment with the activator appliance for soft tissue injury following an rta 5 yrs ago?
Not much: Chiropractic "treatment" is a form of exaggerated massage designed to keep you coming back for steady income. There is little in chiropractic practice or theory which can be considered to have as a goal - cure. If you have a persistent problem you should see your orthopedic physician for a true understanding. ...Read moreSee 1 more doctor answer
Might help: When thromboplastin activator first appeared it was felt dangerous for elderly pts, and only safe if used very early. All of this is now modified and it may be both safe and effective in older pts if additional risk factors are not present. However, still most effective if used as early as possible. ...Read more
Opinion: You may find a variable amount of opinions but from a neurosurgeons perspective, the risk is too high to give tpa to a 95 year old with a stroke. Someone needs to have a frank discussion with the family regarding proper treatment for patients of a certain age. The tpa may work great, but the risks of hemorrhage or other life threatening complications is high. ...Read more
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