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Doctor insights on: Thyroidectomy And Tpo Antibodies

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Suffered from thyroiditis for years and recently had thyroidectomy. What do antibodies attack if gland is removed?

Suffered from thyroiditis for years and  recently had thyroidectomy. What do antibodies attack if gland is removed?

Probably nothing: This is a good question. In most cases, hashimoto's thyroiditis is limited to the thyroid. Thyroid gone (or hypothyroidism) and there is no more inflammation. Presumably those antibodies don't attack anything. But people with hashi can get other autoimmune diseases, such as addison's, type 1 diabetes, pernicious anemia, and others. But this is not common. ...Read more

Dr. Eric Weisman
42 doctors shared insights

Thyroid Peroxidase Antibodies (Definition)

The body uses antibodies to attack and remove foreign substances. Useful as an aid in the diagnosis of thyroid autoimmune disorders; differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism; as a diagnostic tool in deciding whether to treat a patient ...Read more


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Is it possible recurrence of thyroid cancer if thyroglobulin came back positive but antibodies are decreasing? Had full thyroidectomy 2 years ago.

Is it possible recurrence of thyroid cancer if thyroglobulin came back positive but antibodies are decreasing? Had full thyroidectomy 2 years ago.

Need an exam : Thyroglobulin is one of the markers used in follow up. A rise in the value would prompt you to see an Oncologist for a clinical exam, repeat the labs and if necessary order tests like a radio active scan depending on the type of thyroid cancer ...Read more

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6 montes after thyroidectomy and rai, thyroglobuline <0.1 ng/ml and antithyroglobuline antibodies are 47.8 iu/ml. No TSH elevation. Is this good, bad?

6 montes after thyroidectomy and rai, thyroglobuline <0.1 ng/ml and antithyroglobuline antibodies are 47.8 iu/ml. No TSH elevation. Is this good, bad?

Okay: I assume that you had thyroid cancer. If this is the case, you want to be on enough thyroid hormone so that the TSH is in the lower range of normal or slightly low (0.2-1.0). Unfortunately, having thyroglobulin antibodies makes the thyroglobulin level unreliable as an indicator or residual thyroid tissue. ...Read more

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Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Immunity to thyroid: The thyroid makes thyroglobulin (tg) and thyroid peroxidase (tpo). Even though you had your thyroid removed, your body's immune system sees tg and tpo as foreign and has made antibodies to them. This means that following your tg as a way to monitor your thyroid cancer might be unreliable. It could also mean you have thyroid tissue that is still present in your body. Ask your endocrinologist! ...Read more

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I had a total thyroidectomy with pathology of hyalinizing trabecular tumor. But I have thyroglobulin antibodies how come? Also can't get TSH down

Hypothyroidism: The thyroid condition you have is rare and is considered by many a variant of papillary carcinoma which commonly arises in chronic thyroiditis as indicated by your elevated thyroglobulin antibodies. The destruction of normal thyroid cells from chronic inflammation or complete surgical removal leads to hypothyroidism reflected by elevated tsh. See your endocrinologist for treatment. ...Read more

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Anti tpo antibodies 1300. What does this mean?

Hashimotos: This would suggest autoimmune thyroid disease, either hashimotos thyroiditis or graves disease. But it is not diagnostic. See your endocrinologist. ...Read more

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How can you be negative for anti-TPO antibodies if they are detected, even if they are in the normal range? Does anyone have a value of 0 for these?

How can you be negative for anti-TPO antibodies if they are detected, even if they are in the normal range? Does anyone have a value of 0 for these?

Lab practice: This is an arcane subject in clinical pathology. Antibodies are detected based on activities, not the specific identification of molecules. A lab sets a decision level at which an assay is reported as likely to indicate disease, with the understanding that what is really being measured is the ability of all the proteins totaled to bind to the test antigen. ...Read more

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What happens if I have a mild giter and tpo antibodies and antithyroglobulin antibodies is that normal?

What happens if I have a mild giter and tpo antibodies and antithyroglobulin antibodies is that normal?

Hashimoto's : Hi. Sounds like Hashimoto's to me! Is your thyroid function normal? Or not? Did your doc recommend treatment? ...Read more

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My blood endocrinology test report says thyroglobulin antibody more than 1000.00IU/ml and anti TPO antibodies 116.52IU/ml what does it mean plz help?

My blood endocrinology  test report says thyroglobulin antibody more than 1000.00IU/ml and anti TPO antibodies 116.52IU/ml what does it mean plz help?

Thyroid Autoimmune d: It means your Thyroid gland damge caused by the immune system.It may be due to 1Graves Dusease 2Hashimotos Disease or Thyroditis 3Hypothyroidism 4Thyrotoxicosis You must have had other tests likeTSH,T3,T4,FREET4 You should discuss with your endocrinologist what condition you have and thr recommended treatment ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


Dr. Mark Loury
345 doctors shared insights

Thyroidectomy (Definition)

This is the removal of all or part of the thyroid gland. It is generally performed for rumors of the gland, occasionally for enlarged and hyper functioning glands that do ...Read more