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Doctor insights on: Thyroid Therapy Cause Adrenal Crisis

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Why does thyroid replacement therapy in hypoadrenalism cause adrenal crisis?

Why does thyroid replacement therapy in hypoadrenalism cause adrenal crisis?

Great question!: Even people with adrenal problems often make a little bit of cortisol. This little bit can be enough to keep them from getting very sick. In hypothyroidism the body's need for cortisol goes down and the little bit you make lasts longer. So if a person has both thyroid and adrenal disease, treating the thyroid without treating the adrenal problem first causes the little cortisol to run out quicker. ...Read more

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Dr. Payam Rafat
124 doctors shared insights

Addisonian Crisis (Definition)

Addisonian or acute adrenal crisis is a life-threatening condition that occurs when there is not enough cortisol, a hormone produced by the adrenal glands. It can manifest with fatigue, nausea, poor appetite, fever, joint pain, fatigue, coma, or seizure. Addison's disease is usually treated ...Read more


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In context of cryofibrinogenemia, lupus-type ctd and adrenal insufficiency, what could cause increase in GI symptoms, nausea, and vomiting with adrenal crisis, when estrogen/progestin drugs are taken?

In context of cryofibrinogenemia, lupus-type ctd and adrenal insufficiency, what could cause increase in GI symptoms, nausea, and vomiting with adrenal crisis, when estrogen/progestin drugs are taken?

Cortisol deficiency : With true adrenal insufficiency diagnosed by an endocrinologist, one would need to be taking cortisol replacement therapy. Nausea, abdominal pain, vomiting and weight loss are classic symptoms of adrenal insufficiency which estrogen and Progesterone replacement don't address. Many with primary adrenal insufficiency also look like they have a deep tan. ...Read more

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Can a traumatic experience cause an adrenal crisis?

Can a traumatic experience cause an adrenal crisis?

Possible: Of it leads to significant hemorrhage (bleed) within the adrenal gland. Ask your doctor to check your morning cortisol and if low you may need adrenal dynamic studies ( typically done in an endocrine office setting). ...Read more

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Can triamcinolone cream cause adrenal crisis if I stop using suddenly? I use it on & off for my eczema. Sometimes for long periods.

Can triamcinolone cream cause adrenal crisis if I stop using suddenly? I use it on & off for my eczema. Sometimes for long periods.

No: Topical steroids are not absorbed enough, even with long term use, to cause adrenal suppression. Thus, no risk of adrenal crisis with their discontinuation. Make sure you are doing everything possible medication free (moisturizers/emollients/sunscreen) though to try and decrease use of the topical steroids for your eczema. ...Read more

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Is there a kind of hyper thyroidism that resolves without treatment ?

Is there a kind of hyper thyroidism that resolves without treatment ?

Yes: Dequervain's thyroiditis can make you hyperthyroid for a few days or weeks then self-cure. Another cause is eating beef into which the animal's thyroid was accidentaly placed by the butcher. ...Read more

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What should people treated with HGH know about adrenal crisis?

What should people treated with HGH know about adrenal crisis?

In general, nothing: Hgh tx does not involve the hypothalamic-pituitary-adrenal axis, & should not produce adrenal suppression or increased risk for an adrenal crisis. The pre-treatment evaluation should have included a broader assessment of the patient's hormones and should have identified a possible acth deficiency. If such deficiency were present but unrecognized, there would in fact be risk of an adrenal crisis. ...Read more

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What is acute adrenal crisis?

What is acute adrenal crisis?

Low cortisol state: Acute adrenal crisis is defined by the sudden drop in Hydrocortisone (or its equivalent) in the body, prompting acute physiological changes such as low blood sugar, lethargy, nausea, low blood pressure and sometimes even coma and death. Immediate steroid replacement is needed to reverse the above either via mouth (if the individual is stable and able to swallow) or via intra muscular/intravenous. ...Read more

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What exactly is an adrenal crisis?

Life threatening: Your adrenal glands make hormones which help to maintain normal salt and sugar levels in your blood as well as normal blood pressure. An adrenal crisis is a severe presentation of adrenal insufficiency which is life threatening due to potential problems with severely low blood pressure, in addition to very abnormal salt and sugar levels. ...Read more

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What should I do if I experience an adrenal crisis?

Why would it happen?: What makes you think you will have an adrenal crisis. Did you have adrenalectomy or addison's disease? Did your doctor advise you to wear a medic alert bracelet? ...Read more

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Dr. Michael Gabor
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more