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Doctor insights on: Thyroid Peroxidase Antibodies

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Dr. Gerald Mandell
37 doctors shared insights

Thyroid Peroxidase Antibodies (Overview)

The body uses antibodies to attack and remove foreign substances. Useful as an aid in the diagnosis of thyroid autoimmune disorders; differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism; as a diagnostic tool in deciding whether to treat a patient who has subclinical hypothyroidism.


Dr. David Geffner
Board Certified, Endocrinology
48 years in practice
2M people helped
1

1
What are thyroid peroxidase antibodies?

What are thyroid peroxidase antibodies?

Thyroid antibody: They are made by your own wbcs directed against peroxidase, an enzyme on the thyroid microsome. People with hashimoto's and graves' diseases may have + antibodies to the thyroid peroxidase. ...Read more

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Dr. Jack Hinkle
Board Certified
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Dr. Gerald Mandell
37 doctors shared insights

Thyroid Peroxidase Antibodies (Overview)

The body uses antibodies to attack and remove foreign substances. Useful as an aid in the diagnosis of thyroid autoimmune disorders; differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism; as a diagnostic tool in deciding whether to treat a patient who has subclinical hypothyroidism.


Dr. Dan Fisher
Board Certified, Internal Medicine
21 years in practice
78M people helped
2

2
Regarding thyroid peroxidase antibodies, if I am positive, should my kids all be checked?

Regarding thyroid peroxidase antibodies, if I am positive, should my kids all be checked?

No.: Anti tpo ab are not inherited directly. If your child develops signs and symptoms of hypothyroidism it might be reasonable to check a tsh, but not tpo. ...Read more

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Dr. Jack Hinkle
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Dr. Juan Merayo-Rodriguez
Board Certified, Pathology
17 years in practice
193K people helped
3

3
What is the definition or description of: thyroid peroxidase antibodies?

What is the definition or description of: thyroid peroxidase antibodies?

Thyroperoxidase(TPO): The body uses antibodies to attack and remove foreign substances. Useful as an aid in the diagnosis of thyroid autoimmune disorders; differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism; as a diagnostic tool in deciding whether to treat a patient who has subclinical hypothyroidism. ...Read more

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Dr. Michael P Vaughn
Board Certified, Allergy and Immunology
28 years in practice
1M people helped
4

4
Negative result for thyroid peroxidase antibodies tpoab . Necessary to test my thyroglobulin antibodies tgab ?

Negative result for thyroid peroxidase antibodies  tpoab .  Necessary to test my thyroglobulin antibodies  tgab ?

Anti-thyroglobulin: Studies have shown that 99% of patients with hashimoto's thyroiditis have anti-microsomal antibodies, whereas only about 1/3rd had anti-thyroglobulin antibodies. In addition, 10-20% of persons without thyroid problems have anti-throglobulin antibodies (tg-a). These persons are likely at higher risk for future problems and should be watched more closely however, testing for tg-a is not necessary. ...Read more

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Dr. Jack Hinkle
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Dr. Thomas Knecht
Board Certified, Endocrinology
25 years in practice
5M people helped
5

5
Thyroid Peroxidase Antibodies 274.0 Anti-Thyroglobulin Antibody 164.4 Mean Platelet Volume 9.1 Erythrocyte Sed Rate 26 Estimat Glomerular Filtratio 43?

Thyroid Peroxidase Antibodies 274.0
Anti-Thyroglobulin Antibody 164.4
Mean Platelet Volume 9.1
Erythrocyte Sed Rate 26
Estimat Glomerular Filtratio 43?

Thyroid and kidneys: Hi. You have antibody evidence of thyroid autoimmunity. It would be nice to know your TSH and free T4. Are you on thyroid hormone? You have diminished kidney function. Do you know why? ...Read more

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Dr. David Geffner
Board Certified, Endocrinology
48 years in practice
2M people helped
6

6
Any reason for a high level for thyroid peroxidase antibody other than hypothyroidism?

Any reason for a high level for thyroid peroxidase antibody other than hypothyroidism?

Yes and no: A positive tpo antibody merely means that you may have hashimoto's disease. The wickham and framingham studies show that people with + abs will eventually get hypothyroid. + abs are also seen in patients with hyperthyroidism due to graves" disease. ...Read more

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Dr. David Sneid
Board Certified, Endocrinology
35 years in practice
38M people helped
7

7
What are the normal thyroid peroxidase antibodies?

What are the normal thyroid peroxidase antibodies?

Usually very low: Tpo antibodies are generally low or absent unless you have had hashimoto's thyroiditis. Once they occur, they may decline slowly or last a lifetime. ...Read more

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Dr. David Sneid
Board Certified, Endocrinology
35 years in practice
38M people helped
8

8
Thyroid peroxidase antibody level is 200. What does that mean?

Prior thyroiditis: It means you have had prior thyroiditis at some time in the past. Repeated episodes of thyroiditis can possibly lead to an underactive thyroid in the future. ...Read more

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Dr. Dan Fisher
Board Certified, Internal Medicine
21 years in practice
78M people helped
9

9
Regarding thyroid peroxidase antibodies, if I am positive, should my kids all be checked?

No.: Anti tpo ab are not inherited directly. If your child develops signs and symptoms of hypothyroidism it might be reasonable to check a tsh, but not tpo. ...Read more

Get help from a doctor now ›
Dr. David Sneid
Board Certified, Endocrinology
35 years in practice
38M people helped
10

10
What are the normal thyroid peroxidase antibodies?

Usually very low: Tpo antibodies are generally low or absent unless you have had hashimoto's thyroiditis. Once they occur, they may decline slowly or last a lifetime. ...Read more

Get help from a doctor now ›

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


Dr. Michael Gabor
12 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more


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Dr. Jack Hinkle
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