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Doctor insights on: Thyroid Nodules Cancerous Synthroid

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Are thyroid nodules less likely to be cancerous when I have been taking Synthroid (thyroxine) for 20 years?

Are thyroid nodules less likely to be cancerous when I have been taking Synthroid (thyroxine) for 20 years?

Not always: There is a slight increased risk of thyroid cancer in people with hashimoto's thyroiditis, the most common cause of hypothyroidism. If the nodule(s) have been stable for 20 years, they are unlikely to be cancerous. Any new nodules are assumed to be suspicious and should have an ultrasound and possibly a biopsy. ...Read more

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Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Are thyroid nodules more or less likely to be cancerous when one has been taking Synthroid (thyroxine) for 20 years?

Are thyroid nodules more or less likely to be cancerous when one has been taking Synthroid (thyroxine) for 20 years?

Depends: If autoimmune thyroiditis is the reason you are hypothyroid, then there is about a 3 fold increase in risk for developing thyroid cancer over those who don't have anti thyroid antibodies. Having said that, thyroid cancer is still relatively uncommon despite a growing incidence. ...Read more

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Thyroid nodules on left and right side. Fna showed papillary cancer. Synthroid (thyroxine) 50mcg/day. Nodules dicresed since 4/2012. Okay to wait 6 mo. For surg?

Thyroid nodules on left and right side. Fna showed papillary cancer. Synthroid (thyroxine) 50mcg/day. Nodules dicresed since 4/2012. Okay to wait 6 mo. For surg?

I wouldn't: The longer there is cancer, the longer it can work its way out of the thyroid capsule, grow, and spread via the lymph nodes. As this occurs, the prognostic factors worsen. ...Read more

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Can 50mcg of Synthroid (thyroxine) make thyroid nodules grow?

Can 50mcg of Synthroid (thyroxine) make thyroid nodules grow?

NO: Thyroid supplementation occasionally can help to shrink a nodule, and has been used to suppress the growth. ...Read more

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I'm confused aftr readng!.Have thyroid nodules.Ws on synthroid (thyroxine).10 yrs later, diff.Dr took off syn. Ok for no treatment w/nodules dr.Rarely ultrasnds?

I'm confused aftr readng!.Have thyroid nodules.Ws on synthroid (thyroxine).10 yrs later, diff.Dr took off syn. Ok for no treatment w/nodules dr.Rarely ultrasnds?

Evolving knowledge: In the past it is not uncommon for people with thyroid nodules to be started on levothyroxine supplementation. The logic was high dose thyroxine would keep the nodule from growing. Studies have failed to prove this and most endocrinologists gave up the practice of prescribing levothyroxine suppression for thyroid nodules. Most thyroid nodules are benign(>95%) , long history is reassuring in ur cas. ...Read more

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Are cold thyroid nodules cancerous?

Only occassionally: While almost all thyroid cancers are cold, so are most benign nodules. If the nodule is hot, it is extremely rare for it to be cancer. If it is cold and looks suspicious on an ultrasound performed or at least interpreted by a very experienced clinician, it should be biopsied to see if surgery is necessary. ...Read more

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Are all types of thyroid nodules/lumps cancerous?

Are all types of thyroid nodules/lumps cancerous?

Thyroid nodules: No, most thyroid nodules are not cancerous. A thyroid ultrasound is very sensitive at picking up tiny and often insignificant nodules. There are some features of thyroid nodules that make them more suspicious, such as large solitary "cold" ones, and other features. The best person to evaluate is an Endocrinologist who does his/her own U/S guided biopsies. ...Read more

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Are all types of thyroid nodules / lumps cancerous?

Are all types of thyroid nodules / lumps cancerous?

No: The majority of lumps in the thyroid when noted to be multiple on scan represent the condition "multinodular goiter" These are almost always benign. When a solitary lesion is present that is "cold" on isotope scan, this is suspicious for possible malignancy and should always be removed. Bx has a certain degree of error especially if a follicular lesion looking benign has invaded capsule. ...Read more

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Thyroid nodules and cancer. What % of nodules are cancer?

Thyroid nodules and cancer. What % of nodules are cancer?

Varies: The likelihood of a thyroid nodule being cancer is about 10-20%. The incidence is higher with prior history of radiation (20-40%) and in patients with multiple endocrine neoplasia. ...Read more

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Can cystic thyroid nodule be cancerous?

Can cystic thyroid nodule be cancerous?

Unlikely but ask doc: Most of the the thyroid nodules are benign, cystic nodules are even more benign, but sometimes a small focus of cancer could be inside the cyst, to be sure most of the time after fine needle aspiration (fna) will be done by your doctor send for biopsy ( cytology ) to be sure it is benign.. ...Read more

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Nodule (Definition)

Any growth or deposit in the body or on its surface may be casually termed a nodule until its character is determined by the familiarity of the physician with it or by the results of a biopsy if it is not so obvious. The term is casual ...Read more


Dr. Thomas Inwood
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more