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Doctor insights on: Thyroid Is Positive For Autoimmune Disorder

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Is hashimotos an endocrine or autoimmune disorder?

Is hashimotos an endocrine or autoimmune disorder?

Both: Hashimoto's thyroiditis occurs when the body produces antibodies directed against the thyroid gland, which could eventually render it unable to produce thyroid hormones. When that happens, a patient becomes hypothyroid. ...Read more

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Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


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Should a typical blood test for autoimmune diseases detect thyroid graves disease?

Should a typical blood test for autoimmune diseases detect thyroid graves disease?

Not necessarily: A tsh-receptor antibody would be the more appropriate blood test to test for graves disease. ...Read more

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Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?

Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?

No: When there is a total deficiency of the immunoglobulin, there can be no autoantibody formed from that particular class of immunoglobulin. Thus it is not a masking. However this does not rule out that other immune mechanisms may not be the cause for a certain illness. ...Read more

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Is there a test for acth antibodies in an, depression and other stress disorders?

Is there a test for acth antibodies in an, depression and other stress disorders?

Not to my knowledge: There's a pop / speculative literature about "hypothalamic - pituitary - adrenal axis disease" in people with anxiety, depression and vulnerability to life's stresses. The vicissitudes of life are known to alter the hormones in this system, but most folks here probably think the focus should remain on learning new life skills, ways to manage your inner life & getting help with situations. ...Read more

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Autoimmune hypothyroidism (autoimmune thyroiditis) - how common is this disorder?

Autoimmune hypothyroidism (autoimmune thyroiditis) - how common is this disorder?

Common : It is a common autoimmune disorder and we see it a lot. It can overlap with other autoimmune disorders and is a common cause of a positive ana. It is also known as hashimotos thyroiditis. ...Read more

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What is a thyroid peroxidase antibody test? Does it diagnose thyroid disease?

What is a thyroid peroxidase antibody test? Does it diagnose thyroid disease?

Thyroid peroxidase (TPO), an enzyme normally found in the thyroid gland, plays an important role in the production of thyroid hormones: A TPO test detects antibodies against TPO in the blood. If you've been diagnosed with thyroid disease, your doctor may recommend a TPO antibody test — in addition to other thyroid tests — to help determine the cause. The presence of TPO antibodies in your blood suggests that the cause of thyroid disease is an autoimmune disorder, such as Hashimoto's disease or Graves' disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue. Antibodies that attack the thyroid gland cause inflammation and impaired function of the thyroid. Your doctor may also order a TPO antibody test if you are pregnant and have an autoimmune disease, especially one that involves the thyroid, such as Hashimoto's disease or Graves' disease. Some people with TPO antibodies may not have thyroid disease. However, the presence of TPO antibodies may increase the risk of future thyroid disorders. If you have normal thyroid function with TPO antibodies, your doctor may recommend periodic checkups to watch for future thyroid problems. ...Read more

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Any reason for a high level for thyroid peroxidase antibody other than hypothyroidism?

Any reason for a high level for thyroid peroxidase antibody other than hypothyroidism?

Yes and no: A positive tpo antibody merely means that you may have hashimoto's disease. The wickham and framingham studies show that people with + abs will eventually get hypothyroid. + abs are also seen in patients with hyperthyroidism due to graves" disease. ...Read more

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Would an ANA blood test be positive in someone with sarcoid since it is an autoimmune disorder?

Would an ANA blood test be positive in someone with sarcoid since it is an autoimmune disorder?

ANA not in sarcoid: ANA, or anti-nuclear antibody, is a sensitive and specific test for systemic lupus erythematosus only at high titer >1:320. A low titer positive ANA, such as 1:40 may be detected in up to 1 in 10 HEALTHY women. Sarcoidosis is a disease of hyperactive immune cells BUT it is not characterized by specific antibodies like ANA. Someone with sarcoid would not be expected to have a high-titer ANA. ...Read more

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Is polymyalgia rheumatica autoimmune if ANA is negative or result of old age?

PMR likely autoimm: So ANA is probably the most misinterpreted test by almost everyone: it is just a screen for autoimmunity, but not all autoimmunity. And a positive ANA does not mean disease. So, pmr is ANA negative, but still may represent an autoimmune condition. What the autoimmune target is remains unclear though. True, it is exclusively seen in older (>50-60 yo) people, and this remains unclear why also. ...Read more

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Is hyperthyroid a metabolic disorder?

Is hyperthyroid a metabolic disorder?

Yes, in a way!: Thyroid hormones affect metabolism. High levels (above normal) are usually caused by grave's disease, solitary functioning nodule, and taking too much thyroid medication. Hgiher than normal thyroid levels increase your bodies sensitivity to catecholamines, thereby raising heart rate, increasing body heat, and sometimes causing weight loss. This is an unatural state and should be corrected. ...Read more

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How common is discoid lupus in low thyroid disorder?

How common is discoid lupus in low thyroid disorder?

Hard to say/unknown,: Discoid lupus just involves the skin, not the rest of the body. However, a person might have low thyroid in addition to this disorder, or they might have a full case of lupus with skin lesions. Lupus can present with fatigue and so thyroiditis might have to be considered and ruled out. So it is hard to say how often these two dieases are associated. ...Read more

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Deciphering a thyroid hormone test result: is an antithyroglobulin antibody titer of 1:50 too high, or is it alright?

Deciphering a thyroid hormone test result: is an antithyroglobulin antibody titer of 1:50 too high, or is it alright?

It depends: Antithyroglobulin antibody is not a thyroid hormone test. It tells you nothing about the function of your thyroid. It can indicate that you have autoimmune thyroid disease, but your level is not very high. Mild elevations are non-specific and occur more commonly in the population as we get older. Thyroid function is indicated by t4, tsh, and T3 (liothyronine) levels. ...Read more

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Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Immunity to thyroid: The thyroid makes thyroglobulin (tg) and thyroid peroxidase (tpo). Even though you had your thyroid removed, your body's immune system sees tg and tpo as foreign and has made antibodies to them. This means that following your tg as a way to monitor your thyroid cancer might be unreliable. It could also mean you have thyroid tissue that is still present in your body. Ask your endocrinologist! ...Read more

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What is the most desirable TSH level for a person with confirmed hashimoto's hypothyroidism?

What is the most desirable TSH level for a person with confirmed hashimoto's hypothyroidism?

No single number: Normal TSH levels range from 0.4 - 4.0 miu/l. Tsh levels is one of the measures for following treatment and it is usually not a good idea to treat a lab value. ...Read more

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Is it true that anti-inflammatories suppress antibodies for autoimmune diseases or Lyme disease?

Is it true that anti-inflammatories suppress antibodies for autoimmune diseases or Lyme disease?

Not usually : The most common anti-inflammatories are nsaids and these are not considered immunosuppressive's. Corticosteroids may have somewhat of an immunosuppressive effect. And biologics which are used for autoimmune disease but not lyme disease can be immunosuppressive ad well as anti-inflammatory. ...Read more

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Disease processes associated with a high positive ANA other than autoimmune disorders?

Positive ANA: Conditions that can result in an elevated ANA include autoimmune disorders, certain drugs, uncommon infections, chronic lung or liver disease, kidney failure, ultraviolet light therapy, malignancy, pregnancy, and false positive/lab error. Hope this helps. ...Read more

Dr. Steven Griggs
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more