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Doctor insights on: Thyroid Is Positive For Autoimmune Disorder

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Is hashimotos an endocrine or autoimmune disorder?

Is hashimotos an endocrine or autoimmune disorder?

Both: Hashimoto's thyroiditis occurs when the body produces antibodies directed against the thyroid gland, which could eventually render it unable to produce thyroid hormones. When that happens, a patient becomes hypothyroid. ...Read more

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Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


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Should a typical blood test for autoimmune diseases detect thyroid graves disease?

Should a typical blood test for autoimmune diseases detect thyroid graves disease?

Not necessarily: A tsh-receptor antibody would be the more appropriate blood test to test for graves disease. ...Read more

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Dr. John Chiu Dr. Chiu
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Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?

Dr. John Chiu Dr. Chiu
2 doctors agreed:
Could an immunoglobulin deficiency effectively mask an autoimmune disorder from auto-antibody screens such as AMA ANA etc.or is it a separate thing ?

No: When there is a total deficiency of the immunoglobulin, there can be no autoantibody formed from that particular class of immunoglobulin. Thus it is not a masking. However this does not rule out that other immune mechanisms may not be the cause for a certain illness. ...Read more

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Is there a test for acth antibodies in an, depression and other stress disorders?

Is there a test for acth antibodies in an, depression and other stress disorders?

Not to my knowledge: There's a pop / speculative literature about "hypothalamic - pituitary - adrenal axis disease" in people with anxiety, depression and vulnerability to life's stresses. The vicissitudes of life are known to alter the hormones in this system, but most folks here probably think the focus should remain on learning new life skills, ways to manage your inner life & getting help with situations. ...Read more

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Autoimmune hypothyroidism (autoimmune thyroiditis) - how common is this disorder?

Autoimmune hypothyroidism (autoimmune thyroiditis) - how common is this disorder?

Common : It is a common autoimmune disorder and we see it a lot. It can overlap with other autoimmune disorders and is a common cause of a positive ana. It is also known as hashimotos thyroiditis. ...Read more

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What is a thyroid peroxidase antibody test? Does it diagnose thyroid disease?

What is a thyroid peroxidase antibody test? Does it diagnose thyroid disease?

Thyroid peroxidase (TPO), an enzyme normally found in the thyroid gland, plays an important role in the production of thyroid hormones: A TPO test detects antibodies against TPO in the blood. If you've been diagnosed with thyroid disease, your doctor may recommend a TPO antibody test — in addition to other thyroid tests — to help determine the cause. The presence of TPO antibodies in your blood suggests that the cause of thyroid disease is an autoimmune disorder, such as Hashimoto's disease or Graves' disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue. Antibodies that attack the thyroid gland cause inflammation and impaired function of the thyroid. Your doctor may also order a TPO antibody test if you are pregnant and have an autoimmune disease, especially one that involves the thyroid, such as Hashimoto's disease or Graves' disease. Some people with TPO antibodies may not have thyroid disease. However, the presence of TPO antibodies may increase the risk of future thyroid disorders. If you have normal thyroid function with TPO antibodies, your doctor may recommend periodic checkups to watch for future thyroid problems. ...Read more

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Any reason for a high level for thyroid peroxidase antibody other than hypothyroidism?

Any reason for a high level for thyroid peroxidase antibody other than hypothyroidism?

Yes and no: A positive tpo antibody merely means that you may have hashimoto's disease. The wickham and framingham studies show that people with + abs will eventually get hypothyroid. + abs are also seen in patients with hyperthyroidism due to graves" disease. ...Read more

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Would an ANA blood test be positive in someone with sarcoid since it is an autoimmune disorder?

Would an ANA blood test be positive in someone with sarcoid since it is an autoimmune disorder?

ANA not in sarcoid: ANA, or anti-nuclear antibody, is a sensitive and specific test for systemic lupus erythematosus only at high titer >1:320. A low titer positive ANA, such as 1:40 may be detected in up to 1 in 10 HEALTHY women. Sarcoidosis is a disease of hyperactive immune cells BUT it is not characterized by specific antibodies like ANA. Someone with sarcoid would not be expected to have a high-titer ANA. ...Read more

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Is polymyalgia rheumatica autoimmune if ANA is negative or result of old age?

PMR likely autoimm: So ANA is probably the most misinterpreted test by almost everyone: it is just a screen for autoimmunity, but not all autoimmunity. And a positive ANA does not mean disease. So, pmr is ANA negative, but still may represent an autoimmune condition. What the autoimmune target is remains unclear though. True, it is exclusively seen in older (>50-60 yo) people, and this remains unclear why also. ...Read more

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Is hyperthyroid a metabolic disorder?

Is hyperthyroid a metabolic disorder?

Yes, in a way!: Thyroid hormones affect metabolism. High levels (above normal) are usually caused by grave's disease, solitary functioning nodule, and taking too much thyroid medication. Hgiher than normal thyroid levels increase your bodies sensitivity to catecholamines, thereby raising heart rate, increasing body heat, and sometimes causing weight loss. This is an unatural state and should be corrected. ...Read more

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How common is discoid lupus in low thyroid disorder?

How common is discoid lupus in low thyroid disorder?

Hard to say/unknown,: Discoid lupus just involves the skin, not the rest of the body. However, a person might have low thyroid in addition to this disorder, or they might have a full case of lupus with skin lesions. Lupus can present with fatigue and so thyroiditis might have to be considered and ruled out. So it is hard to say how often these two dieases are associated. ...Read more

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Deciphering a thyroid hormone test result: is an antithyroglobulin antibody titer of 1:50 too high, or is it alright?

Deciphering a thyroid hormone test result: is an antithyroglobulin antibody titer of 1:50 too high, or is it alright?

It depends: Antithyroglobulin antibody is not a thyroid hormone test. It tells you nothing about the function of your thyroid. It can indicate that you have autoimmune thyroid disease, but your level is not very high. Mild elevations are non-specific and occur more commonly in the population as we get older. Thyroid function is indicated by t4, tsh, and T3 (liothyronine) levels. ...Read more

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Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Immunity to thyroid: The thyroid makes thyroglobulin (tg) and thyroid peroxidase (tpo). Even though you had your thyroid removed, your body's immune system sees tg and tpo as foreign and has made antibodies to them. This means that following your tg as a way to monitor your thyroid cancer might be unreliable. It could also mean you have thyroid tissue that is still present in your body. Ask your endocrinologist! ...Read more

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What is the most desirable TSH level for a person with confirmed hashimoto's hypothyroidism?

What is the most desirable TSH level for a person with confirmed hashimoto's hypothyroidism?

No single number: Normal TSH levels range from 0.4 - 4.0 miu/l. Tsh levels is one of the measures for following treatment and it is usually not a good idea to treat a lab value. ...Read more

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Is it true that anti-inflammatories suppress antibodies for autoimmune diseases or Lyme disease?

Is it true that anti-inflammatories suppress antibodies for autoimmune diseases or Lyme disease?

Not usually : The most common anti-inflammatories are nsaids and these are not considered immunosuppressive's. Corticosteroids may have somewhat of an immunosuppressive effect. And biologics which are used for autoimmune disease but not lyme disease can be immunosuppressive ad well as anti-inflammatory. ...Read more

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Disease processes associated with a high positive ANA other than autoimmune disorders?

Positive ANA: Conditions that can result in an elevated ANA include autoimmune disorders, certain drugs, uncommon infections, chronic lung or liver disease, kidney failure, ultraviolet light therapy, malignancy, pregnancy, and false positive/lab error. Hope this helps. ...Read more

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What should you eat when you have hyper thyroidism?

What should you eat when you have hyper thyroidism?

Hyperthyroidism: There are no food that reverse hyperthyroidism or make it worse. ...Read more

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I had cure autoimune disease I am of 17years can my thyroidism and brain fog due to med can cure.How long i need to take med further?

Thyroiditis?: If you are referring to autoimmune thyroiditis ( hashimoto's disease)- this at first can cause an overactive thyroid ( hyperthyroidism) followed by decreased thyoid function ( hypothyroidism). You need to have your thyroid hormone levels balance to achieve balance. The medication may be need for a lifetime or the disease can resolve. ...Read more

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Is thyroid disease an autoimmune disease or not?

Is thyroid disease an autoimmune disease or not?

Yes: The most common cause of hyperthyroidism is graves' disease. The most common cause of hypothyroidism is hashimoto's thyroid disease. Both of these are autoimmune diseases. ...Read more

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Autoimmune thyroid disease is what?

Immune attack: An autoimmune disease is when the body's immune system mistakenly makes antibodies which are directed towards one's own healthy tissues. In terms of thyroid, antibodies are targeted against the thyroid - very similar in principle to rejecting one's own thryoid. That is, the body is rejecting it's own tissue. ...Read more

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Is it possible to have nothing wrong your thyroid, but still have an autoimmune disease?

Yes: Autoimmune thyroid disease can manifest as an enlarged thyroid, abnormal thyroid antibodies on lab testing, sometimes nodular thyroid, and yet thyroid function can be normal, low, or high. Thyroid functions would be indicated by tsh, t4, T3 (liothyronine) levels. Thyroid ultrasound would look for nodules. There is no treatment for the autoimmune part, but abnormal thyroid function or nodules can be treated. ...Read more

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If I have an autoimmune thyroid disease would it not be detected in a basic thyroid screen?

If I have an autoimmune thyroid disease would it not be detected in a basic thyroid screen?

Autoimmune thyroid: Autoimmune thyroid disease will not be detected in a basic thyroid screen which refers to T4 and a TSH and not thyroid antibodies. Autoimmune thyroid disease is detected by specific antibodies. Tpoab ( peroxidase antibodies) , tgab ( thyroglobulin antibodies) and trab ( thyroid stimulating receptor ab). Autoimmune thyroiditis is diagnosed by careful exam in conjunction with thyroid ab. ...Read more

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What is the sensitivity of an ANA in autoimmune thyroid disease? Either by ELISA or IIFA

Nonspecific: ANA only suggests that you have a higher risk for autoimmune disease (of which thyroid disease may be one) but is not diagnostic by itself for any illness. ...Read more

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I have thyroid goiter with positive thyroid antibodies; eurothyroid. Does this mean have autoimmune d/o?

I have thyroid goiter with positive thyroid antibodies; eurothyroid. Does this mean have autoimmune d/o?

Not necessarily: Euthyroid means that at the moment you do not have biochemical hypo or hyperthyroidism. Not everyone with positive thyroid antibodies develops autoimmune thyroid disease. However, given that we know that your antibodies are positive, i would have your thyroid tests monitored regularly. How often depends on your doctors opinion. I monitor people like you twice early. ...Read more

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I have either autoimmune pandysautonomia or paraneoplastic syndrome. My anti striational antibody was positive. I have metastatic thyroid ca. Which?

I have either autoimmune pandysautonomia or paraneoplastic syndrome. My anti striational antibody was positive. I have metastatic  thyroid ca. Which?

Complicated: Could be either, and to complicate matters dysautonomia can be cause by a paraneoplastic phenomenon. Either way the primary focus is to first treat the metastqatic thyroid ca and see how the dysautonomia progresses (and hopefully improves). ...Read more

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What's best treatment for autoimmune thyroid disease and how is the treatment different than typical hypothyroidism?

Most often none: Most often the autoimmune process is not treated. We treat hypothyroidism or hyperthyroidism as those are the important consequences of the process. Treating the process itself with immune suppression is theoretically possible, but not done as such treatments can have serious consequences and in thyroid disease do not offer advantages. The only exception is graves' disease with ocular complication. ...Read more

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I have a mass and several hard nodes in my neck. Nodules on my thyroid no infectuon or autoimmune disease. But tell me its "nothing". Any advice?

I have a mass and several hard nodes in my neck. Nodules on my thyroid  no infectuon or autoimmune disease. But  tell me its "nothing". Any advice?

Biopsy?: There are many causes of lumps or nodules in the neck/thyroid. For the thyroid, they may be monitored over time by ultrasound and/or biopsied so that microscopic tissue can be examined (for possible cancer). Protocols for evaluating these are pretty straight forward, but if you have questions for your doctor, then please ask. Sounds like more info about your work-up might put your mind at ease. ...Read more

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Why would autoimmune disorders make the thyroid gland produce excessive thyroxine?

Why would autoimmune disorders make the thyroid gland produce excessive thyroxine?

Antibodies: Some auto-antibodies sit on the thyroid cells and make them over produce thyroid hormone. Other autoantibodies can cause the exact opposite. ...Read more

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Should I ask my doctor to check for other autoimmune diseases if I have hashimotos disease? Meds not helping symptoms even when thyroid level normal

Yes but: If the thyroid level is normal, then your symptoms are not caused by the thyroid but something else. Although you may be at a somewhat higher risk to develop another autoimmune disease , your problem may or may not be an autoimmune one. ...Read more

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I had my thyroid removed 2 yrs ago, t-levels are ok but I have all the symptoms of MS but my MRI is clean, what other autoimmune disease could i have?

I had my thyroid removed 2 yrs ago, t-levels are ok but I have all the symptoms of MS but my MRI is clean, what other autoimmune disease could i have?

"all the symptoms": Do not understand what you are describing, and cannot easily relate your thyroid to ms, or other neurological problems. If you had an immune thyroid issue, you could have other immune problems such as pernicious anemia. Provide more direct information, please. ...Read more

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Does multinodular goiter with slightly elevated thyroid antibodies possibly mean an autoimmune thyroid disease?

Possibly: Thyroiditis (which can be immune based) is the most common cause of a multinodular goiter. Have you doctor test for tpo antibodies if you're concerned. ...Read more

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Will a standard blood test for autoimmune diseases detect thyroid graves disease?

Noit will not: You need to test for special thyroid related antibodies for diagnosis og graves disease. ...Read more

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Should a typical blood test for autoimmune diseases detect thyroid graves disease?

Not necessarily: A tsh-receptor antibody would be the more appropriate blood test to test for graves disease. ...Read more

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Feel great - incidental finding ANA 1:160 after acute sinusitis. Then had Anti-DNA, Ant-Smith, SSA/SSB, RNP, SCL-70, Centromere, and Thyroid labs all normal. Does this exclude autoimmune disorder?

False positive ANA: ANA positivity very common in general population. You had the correct assessment showing no common autoimmune diseases. A repeat ANA can be 1:80 as you rid infection. It is a non specific test till titers of 1:640. ...Read more

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Positive anti-thyroglobulin (94 iu/ml), negative anti-thyroid peroxidase. Normal TSH levels. thyroid autoimmune? Cancer? Feel mostly symptom free

Positive anti-thyroglobulin (94 iu/ml), negative anti-thyroid peroxidase. Normal TSH levels. thyroid autoimmune? Cancer? Feel mostly symptom free

No indication of: Cancer. From the information you provided, there is no reason to think you have cancer. You should have regular check ups, including thyroid function tests as you are at greater risk for developing thyroid deficiency.For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

Dr. Creighton Wright
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more