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Doctor insights on: Thyroid Hurthle Cell Neoplasm

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Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


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Thyroid nodule came back negative but cells are suspicious for hurthle cell neoplasm. What does that mean?

Thyroid nodule came back negative but cells are suspicious for hurthle cell neoplasm. What does that mean?

Surgical biopsy: Hi. Going just on what you've told us, you probably need a surgical biopsy. A Hurthle cell neoplasm can be either benign or cancer, and the cytopathology often cannot make the distinction. Therefore, to exclude or confirm cancer will require a surgical biopsy. But I don't have the data. Your doc will tell you what's needed. Good luck! ...Read more

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Please would like to know what is meant by thyroid shows well defined follicular neoplasm composed of cells with granular cyloplasm , is it cancer?

Please would like to know what is meant by thyroid shows well defined follicular neoplasm composed of cells with granular cyloplasm , is it cancer?

Need to discuss: With your doctor/endocrinologist. Need more information such as clinical picture, ultrasound results, lab tests etc. This is too important to get diagnosed over the internet. ...Read more

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Can a "normal" thyroid nodule develop abnormal follicular neoplasm cells over time?

Possibly: Ghe tendency for transformation of a nodule in the thyroid gland depends on whether the nodule is solitary or multiple. The latter for the most part is a goiter and rarely if ever associated with Ca of thyroid. A solitary nodule has to be examined as to being hot or cold. If hot and functional Ca essentially doesn't occur. If the solitary nodule cold, there is a 30% chance of converting to Ca. ...Read more

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Fna on a 2.O CM tumor came back as hurthle cell neoplasm. What is the best approach?

Fna on a 2.O CM tumor came back as hurthle cell neoplasm.  What is the best approach?

Surgery: Hurthle cell tumors are adenomas but has higher incidence of malignancy , if they are over 4 cm and in older population , surgical resection is needed , some even advocate total thyroidectomy, instead of lobectomy. ...Read more

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What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read more

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What is the optimal TSH for a 61 year old female who 16 years ago operated thyroid gland due to hurthle cell ca. ? My TSH during all these 16 years (after the operation) was 0, 6 - 0, 4 . But two months ago I changed the original swiss medicine eltr

As : As you know, TSH (thyroid stimulating hormone) is secreted by your pituitary gland to stimulate the synthesis and release of thyroid hormones from your thyroid gland (which has been removed, in your case). Since TSH can also stimulate the growth of thyroid cancer cells, one goal of therapy for thyroid cancer patients is to suppress their TSH to the lowest possible level while keeping their triiodothyronine level (t3) within a normal range. (many physicians strive for a TSH less than 0.1 as long as the patient's T3 (liothyronine) doesn't climb higher than normal). This usually requires a levothyroxine dose between 2.2 and 2.8 mcg per kg of body weight (about 170 to 220 mcg for a 172 lb individual). I hope that helps! ...Read more

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32 years old male. Thyroid Bilateral Multiple nodule, The largest size is 1.5*1.78*0.839 cm. Three times FNA. Result is No EVIDENCE OF MALIGANCY. Comment: Follicular cell, Hurthle cell and colloid are seen. I worry about the Hurthle cell. My Surgeons only

32 years old male. Thyroid Bilateral Multiple nodule, The largest size is 1.5*1.78*0.839 cm. Three times FNA. Result is No EVIDENCE OF MALIGANCY. Comment: Follicular cell, Hurthle cell and colloid are seen. I worry about the Hurthle cell. My Surgeons only

Thyroid nodules: Usually we worry about a solitary nodule in a male and it appears that you are in good hands and the biopsies are reassuring. For further reassurance we depend on a combination of an endocrinologist or thyroidologist and a surgeon skilled in thyroid surgery reviewing your findings and I would be quite comfortable with their advice and follow-up. ...Read more

Dr. Sanjiv Kaul
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more