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Doctor insights on: Thyroid Hurthle Cell Neoplasm

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Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


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Do papillary and follicular thyroid cancers secrete thyroglobulin?

Do papillary and follicular thyroid cancers secrete thyroglobulin?

Yes: All cells of thyroid origin secrete thyroglobulin. Measuring it to follow a cancer ONLY makes since if the whole thyroid has been removed. If you have anti thyroglobulin antibodies, that makes thyroglobulin measurements unreliable. However, rising or decreasing anti thyroglobulin antibodies can be a proxy for thyroglobulin measurements. ...Read more

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Cana follicular thyroid lesion turn malignant?

Cana follicular thyroid lesion turn malignant?

Follicular cancer: Follicular thyroid cancer the second most common cancer, after papillary. A thyroid nodule over 2.0 cm, positive/suspicious fna or symptoms are indications for thyroid lobe resection. Final pathology is often where a cancer diagnosis is made. Follicular thyroid cancer is treatable and has a good prognosis. So yes, it can turn into cancer, you need to be monitored closely. Okay to see surgeon. ...Read more

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Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder. Is this lymphoma?

Pathologic diagnosis....Resected thymus shows reactive b cell hyperplasia vs low grade b cell lympho proliferative disorder.  Is this lymphoma?

Could be...: Certain lymphomas grow so slow that sometimes it is difficult for the pathologist to make the call between malignant or not. I suspect they may do additional work on the specimen and that your doctor will evaluate you further with labs, additional scans or another biopsy. If you have not seen a hematologist, maybe this is the time. Don't panic, just follow up his/her lead. Best to you. ...Read more

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Cn thyroid scan diffrentiate between benign n malignant follicular neoplsm?

Cn thyroid scan diffrentiate between benign n malignant follicular neoplsm?

NO : Hi. Nope, you need tissue (cells). Either an FNA for cytology (which may be non-diagnostic) or a surgical biopsy. Scan adds nothing to the diagnostic evaluation ...Read more

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Thyroid fnac report-atypia of undetermined significance or follicular neoplasm. What it means? Treatment?

Thyroid FNA: Hi. A follicular neoplasm of undetermined significance means the cytology doesn't meet criteria for cancer or benign, thus the "undetermined significance". Historically, most of these turn out to be benign, but a significant subset are cancer. It appears they did not do gene testing. Next step would usually be surgical excision of the nodule, frozen section analysis, then total thyroidectomy if CA ...Read more

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Is follicular thyroid carcinoma treatable?

Is follicular thyroid carcinoma treatable?

Very treatable: Surgical resection always needed but depending on size of lesion, proximity to isthmus and whether nodes seen on scan procedure of choice decided on. Under 30 years of age lesion very curable even in face of nodes. Over 50 I find surgery may be difficult because of invasion occasionally into larynx and carotid artery. If surgery effective may need p.o. RT. ...Read more

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What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read more

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Papillary thyroid cancer follicular variant, what to do?

Papillary thyroid cancer follicular variant, what to do?

Remove lesion: The presence of cancer of the thyroid is best handled by thyroid resection. Depending on the size and location, a lobectomy or total thyroidectomy should be performed. Lymph nodes if present are resected. Radical neck not ut9ilized for node removal. Post oo radio iodine may be indicated and use of those meds to compensate for those anatomical structures removed. ...Read more

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Abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages and colloid present, favor adenomatoid nodule. ?

Glad to hear it: Your thyroid nodule is benign. You may have several and they are probably benign as well. Nobody knows what causes these little adenomatous nodules, but they have very little tendency to turn bad. ...Read more

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What is papillary thyroid carcinoma with tall cell variant?

More aggressive: This is a form of thyroid cancer that has a worse prognosis than the typical papillary cancer. It is not the worst form of thyroid cancer. This is also associated with a mutation in the cancer cells call b-raf. There are some new drugs that attack this kind of tumor in later stage. ...Read more

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What is "rare epithelioid giant cells" in fna of thyroid nodules?

What is "rare epithelioid giant cells" in fna of thyroid nodules?

Review with your MD: Usually, when one aspirates a thyroid cyst one may see "rare epithelioid giant cells". Most simple cysts of the thyroid are benign. However, fine needle aspirate of cystic papillary thyroid carcinoma may also show this feature and may lack diagnostic cells. So, additional information is needed to interpret the cytology report. ...Read more

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Is infiltrative basal cell carcinoma an aggressive cancer?

Is infiltrative basal cell carcinoma an aggressive cancer?

Can Be: Usually basal cell carcinoma tend to be less aggressive than some other types of skin cancers. Here is a good resource for more on the topic http://www.Cancer.Net/cancer-types/skin-cancer-non-melanoma. ...Read more

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Solitary, solid nodule with intranodular flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Solitary, solid nodule with intranodular  flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Ask your doctor: The doctor who ordered your biopsy has responsibility to explain to you the meaning of the results. If the biopsy shows neoplastic cells, that usually means Cancer cells. But you should get this clarification from your doctor. ...Read more

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What is a papillary thyroid cancer follicular variant?

Type of cancer: Papillary thyroid cancer is the most common type of thyroid cancer. The follicular variant is a subtype named because of how it looks under the microscope. It is treated the same as regular papillary cancer. ...Read more

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What is rare histiocytes and follicular cells in thyroid nodule?

What is rare histiocytes and follicular cells in thyroid nodule?

Incomplete informat: The presence of histiocytes (a type of inflammatory cell) & expected follicular cells in thyroid is not necessarily worrisome. But it depends on your symptoms, & what prompted the biopsy / FNA to begin with. Also, did you have a radioactive iodine exam? (Called "thyroid uptake & scan")? That tells you if the follicle is "functional" or not (making hormone). A hyperfunctional nodule is more worriso ...Read more

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Is hurtle cell neoplasm defined as cancer?

Is hurtle cell neoplasm defined as cancer?

Not necessary: Hurtel cell neoplasm can be adenoma (not cancer) or carcinoma (cancer). There is not much difference between the two with regards to age, sex, or history of head and neck radiation. However, hurtle cell carcinoma (cancer) tends to be larger in size (4.0 +/- 0.4 cm) compared with hurtle cell adenoma (2.4 +/- 0.2 cm). ...Read more

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3cm hyperechoic thyroid nodule with increased vascularity, normal TSH fnac- follicular cell with hyperplastic area. What it indicates?

Uncertain: The fna can only help if it shows cancer. But in your case it is ambiguous, so your doctor should guide you what to do next?...What did he/she suggest as the next step? Most doctors would next recommend either surgical excision or monitor closely for some time and see if it is growing in size in which case it has to be taken out. ...Read more

Dr. James Dukelow
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more