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Doctor insights on: Thyroglobulin Antibodies High After Total Thyroidectomy

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Read this on my lab report "low positive thyroglobulin antibodies are seen in assymptomatic population" what does that mean in real terms?

Read this on my lab report "low positive thyroglobulin antibodies are seen in assymptomatic population" what does that mean in real terms?

Not diagnostic: In general, lab tests are used to support a clinical diagnosis and thus a positive test per se does not provide a diagnosis without abnormal physical findings or symptoms. On many occasions, an abnormal lab test is not associated with any disease condition especially when the value is only slightly abnormal. If you do hundreds of tests on a healthy person, you will likely find something abnormal. ...Read more

Dr. Jeffrey Satinover
27 Doctors shared insights

Thyroglobulin Antibodies (Definition)

Thyroglobulin antibodies are proteins made by the immune system. The immune system is recognizing the thyroid as strange to the body. Thus, this is a marker of autoimmune thyroid disease. It is usually measured to confirm hashimoto's thyroiditis, but can be seen in people without significant thyroid pathology and with normal thyroid levels. It can also be seen with ...Read more


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I had a total thyroidectomy with pathology of hyalinizing trabecular tumor. But I have thyroglobulin antibodies how come? Also can't get TSH down

I had a total thyroidectomy with pathology of hyalinizing trabecular tumor. But I have thyroglobulin antibodies how come? Also can't get TSH down

Hypothyroidism: The thyroid condition you have is rare and is considered by many a variant of papillary carcinoma which commonly arises in chronic thyroiditis as indicated by your elevated thyroglobulin antibodies. The destruction of normal thyroid cells from chronic inflammation or complete surgical removal leads to hypothyroidism reflected by elevated tsh. See your endocrinologist for treatment. ...Read more

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Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Immunity to thyroid: The thyroid makes thyroglobulin (tg) and thyroid peroxidase (tpo). Even though you had your thyroid removed, your body's immune system sees tg and tpo as foreign and has made antibodies to them. This means that following your tg as a way to monitor your thyroid cancer might be unreliable. It could also mean you have thyroid tissue that is still present in your body. Ask your endocrinologist! ...Read more

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Is it possible recurrence of thyroid cancer if thyroglobulin came back positive but antibodies are decreasing? Had full thyroidectomy 2 years ago.

Is it possible recurrence of thyroid cancer if thyroglobulin came back positive but antibodies are decreasing? Had full thyroidectomy 2 years ago.

Recurrence: Rest assured. It is impossible to say you are cancer free, but that is likely. Here's why: the thyroglobulin level is unreliable because you have antibodies. The fact that the antibodies are decreasing can mean that thyroglobulin is decreasing. Antibodies can be a tumor marker surrogate. Continue to follow the antibody trend and get periodic neck ultrasounds. ...Read more

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6 montes after thyroidectomy and rai, thyroglobuline <0.1 ng/ml and antithyroglobuline antibodies are 47.8 iu/ml. No TSH elevation. Is this good, bad?

6 montes after thyroidectomy and rai, thyroglobuline <0.1 ng/ml and antithyroglobuline antibodies are 47.8 iu/ml. No TSH elevation. Is this good, bad?

Okay: I assume that you had thyroid cancer. If this is the case, you want to be on enough thyroid hormone so that the TSH is in the lower range of normal or slightly low (0.2-1.0). Unfortunately, having thyroglobulin antibodies makes the thyroglobulin level unreliable as an indicator or residual thyroid tissue. ...Read more

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Post thyroidectomy (over a year) show elevated. Tsh. And low. Thyroglobulin. What that means?

Post thyroidectomy (over a year) show elevated. Tsh. And low. Thyroglobulin. What that means?

Thyroid in the Dumps: There is a possiblity you may not be taking enough thyroid hormone replacement. Your doctor will likely look a little deeper into your thyroid labs to find an answer. ...Read more

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Why do I have a high thyroglobulin antibodies?

Why do I have a high thyroglobulin antibodies?

Autoimmune: High thyroglobulin antibodies indicate you have autoimmune thyroid problem. See your doctor to figure out which one. ...Read more

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What can cause thyroglobulin antibodies to be high on blood test?

What can cause thyroglobulin antibodies to be high on blood test?

Auto-immune disease: Anti-thyroglobulin antibodies are autoantibodies to thyroid protein and may indicate hashimot thyroiditis. You should consult your doctor for thyroid function tests to see if you need thyroxine supplements. ...Read more

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My thyroglobulin antibodies level was high on my blood test. What does this mean?

Maybe not much: Antibodies to the thyroid may indicate autoimmune thyroid disease, such as Hashimotos thyroiditis or Graves disease. However, thyroglobulin antibodies are relatively non-specific and not very useful. You should ask your doctor why (s)he performed this measurement. ...Read more

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Does an elevated level of thyroglobulin antibodies and calcitonin mean cancer?

Does an elevated level of thyroglobulin antibodies and calcitonin mean cancer?

Elevation.: Thyroglobulin autoantibodies can be present in benign/malignant thyroid disease. If you have a diagnosis of papillary or follicular cancer, their presence can interfere with thyroglobulin as a tumor marker. If autoantibodies rise, that can be a surrogate marker for cancer recurrence. As for calcitonin, it's elevation is clinically significant in cases of primary or recurrent medullary cancer. ...Read more

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Blood test show thyroglobulin antibodies is high (low positive). but TSH, Free T4, and tpo is normal. Should I be concerned?

Blood test show thyroglobulin antibodies is high (low positive). but TSH, Free T4, and tpo is normal. Should I be concerned?

Thyroid disorders: It sounds like your thyroid is functioning well right now, but the high antibody level indicates possible future autoimmune thyroiditis in the future.
I'm not sure why you had this full work up. If you are symptomatic of thyroid disease, you might want to see an endocrinologist even with your normal results. If you do not have symptoms, your doctor may want to monitor your TSH periodically. ...Read more

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My 16 year old son has been complaining of rapid heart beat and sudden sweats. His TSH was perfect but he had elevated thyroglobulin antibodies. What?

My 16 year old son has been complaining of rapid heart beat and sudden sweats. His TSH was perfect but he had elevated thyroglobulin antibodies. What?

Check Heart Also: If his thyroid function is normal, make sure that he is not suffering from intermittant tachycardia or rapid heartrate. This and other causes may occur. Continue seeing the doctor. ...Read more

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I recently had a thyroidectomy, and now have a thyroglobulin level of 0.2. My doctor gave me the choice of doing rai treatments or not. I need advice?

Depends on the stage: Of thyroid cancer and chance of recurrence. If you have a low stage and risk of recurrence, rai is frequently more harmful than beneficial. However, if you had a large tumor, aggressive variant, or metastasis then rai would likely be a good idea. It would also be important to know if it was a stimulated level. ...Read more

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Thyroidectomy & thyroglobulin levels I had my right thyroid gland removed in april 2011 and then when they did the biopsy, it showed cancer cells so they had to remove my left thyroid gland the following week. I had rai in july 2011. I had my 6 month foll

Persistent: Thyroglobulin levels may remain elevated after a total thyroidectomy and rai due to persistent tumor cells in neck lymph nodes, distant metastasis, or residual thyroid tissue remaining from the time of surgery. Some additional tests, like a neck ultrasound and/or a thyroid metastasis scan can be helpful in obtaining an answer. ...Read more

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Why would a hylanizing traebuler adenoma make thyroglobulin antibodies if its benign?

Why would a hylanizing traebuler adenoma make thyroglobulin antibodies if its benign?

It doesn't: You most likely already had tg antibodies before the hyalinizing trabecular adenoma diagnosis is given. Many people has autoimmune thyroid disease with tg antibodies in the background. This has nothing to do with benign or malignant potential although it could cause some problems following thyroglobulin level in the future. ...Read more

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Is there any natural homopathic ways to lower my thyroglobulin antibodies in order to get an accurate thyroglobulin?

Is there any natural homopathic ways to lower my thyroglobulin antibodies in order to get an accurate thyroglobulin?

Unfortunately, no: Hi. It appears you've had treated differentiated thyroid cancer, and your thyroglobulin can't be monitored because of interfering thyroglobulin antibodies (Tg Ab's). Unfortunately, there is no way to lower Tg Ab's. "Natural homeopathic" is fine for the worried well, but not for real disease. Stick to real medicine shown to be safe and effective. There is no real medicine way to lower Tg Ab's. ...Read more

Dr. Brendan Stack Jr.
239 Doctors shared insights

Thyroglobulin (Definition)

A protein found in the thyroid gland and circulating in the bloodstream that binds to thyroid hormone to allow the hormone to travel throughout the body to its target sites without getting damaged or acting ...Read more


Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more