Top
20
Doctor insights on: Thyroglobulin Antibodies

Share
Dr. Barbara Lavi
27 doctors shared insights

Thyroglobulin Antibodies (Overview)

Thyroglobulin antibodies are proteins made by the immune system. The immune system is recognizing the thyroid as strange to the body. Thus, this is a marker of autoimmune thyroid disease. It is usually measured to confirm hashimoto's thyroiditis, but can be seen in people without significant thyroid pathology and with normal thyroid levels. It can also be seen with any autoimmune thyroid disease.


1

1
Negative result for thyroid peroxidase antibodies tpoab . Necessary to test my thyroglobulin antibodies tgab ?

Negative result for thyroid peroxidase antibodies  tpoab .  Necessary to test my thyroglobulin antibodies  tgab ?

Anti-thyroglobulin: Studies have shown that 99% of patients with hashimoto's thyroiditis have anti-microsomal antibodies, whereas only about 1/3rd had anti-thyroglobulin antibodies. In addition, 10-20% of persons without thyroid problems have anti-throglobulin antibodies (tg-a). These persons are likely at higher risk for future problems and should be watched more closely however, testing for tg-a is not necessary. ...Read more

See 1 more doctor answer
Dr. Barbara Lavi
27 doctors shared insights

Thyroglobulin Antibodies (Overview)

Thyroglobulin antibodies are proteins made by the immune system. The immune system is recognizing the thyroid as strange to the body. Thus, this is a marker of autoimmune thyroid disease. It is usually measured to confirm hashimoto's thyroiditis, but can be seen in people without significant thyroid pathology and with normal thyroid levels. It can also be seen with any autoimmune thyroid disease.


2

2
What are thyroid peroxidase antibodies?

What are thyroid peroxidase antibodies?

Thyroid antibody: They are made by your own wbcs directed against peroxidase, an enzyme on the thyroid microsome. People with hashimoto's and graves' diseases may have + antibodies to the thyroid peroxidase. ...Read more

3

3
Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Yes: Both address presence of antibody to the rhyroglobulin molecule made by thyroid gland. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm. ...Read more

See 1 more doctor answer
4

4
Igg gliadin antibodies abnormal means what?

Igg gliadin antibodies abnormal means what?

Exposure: Basically, this your body's memory protein and tells us that, at some point, you've been exposed to the agent (e.g. Virus, substance, etc...). You should check with your doctor/lab about the significance of specific values. ...Read more

5

5
My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

My serum test is negative for endomysial antibody  iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin  antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more

6

6
What does it mean when thyroid peroxidase antibodies 50.2 IU/mL? Thyroglobulin antibodies 18.0 IU/mL?

Not much by itself: Thyroid antibodies are most helpful if you have a low free T4 and a high TSH indicating hypothyroidism which is most often due to autoimmune thyroid inflammation. If those tests are normal you need no treatment but your high antibodies suggest you have an increased risk of developing hypothyroidism somewhere down the road, but many people with antibodies never develop a thyroid problem. ...Read more

7

7
Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

See details: The urine protein is within normal limits. How strongly positive is the igm cardiolipin. Only high levels of positivity have any clinical significance. Why were the tests ordered in the first place? ...Read more

See 1 more doctor answer
8

8
Do elevated gliadin antibodies IgG and IgA mean gluten sensitivity?

Do elevated gliadin antibodies IgG and IgA mean gluten sensitivity?

TTG: I woul recommend having a ttg IgA antibody and possible duodenal bx , in doing so a diagnosis of celiac disease can be made. If if asymptomatic, there may be benefit from a gluten free diet especially if small bowel inflammation noted. ...Read more

See 1 more doctor answer
11

11
My t3is 108.21 T4 is 10.80 n TSH is 5.43.Antinuclear antibodies is negative. Antithyroglobulin antibodies is <15.0.Peroxidase antibodies is h 100.30?

My t3is 108.21 T4 is 10.80 n TSH is 5.43.Antinuclear antibodies is negative. Antithyroglobulin antibodies is <15.0.Peroxidase antibodies is h 100.30?

Hashimoto's: Your labs showed that you have hashimoto's thyroid disease, an autoimmune thyroid disease that will cause hypothyroidism over time. You are currently subclinically hypothyroid but in light of the positive antibodies, you should talk to your doctor to get treated, especially since you are 24 and is at a reproductive age. Good luck, . ...Read more

12

12
Are immune globulin antibodies a injection?

Are immune globulin antibodies a injection?

Yes.: They may be given intravenously, intramuscularly, or subcutaneously depending on the dose and usage. ...Read more

13

13
Igg gliadin antibodies abnormal, what to do?

More Testing: IgG antibodies to gliadin may be a sign of celiac disease. Especially if you are having chronic diarrhea. You need additional testing with your doctor including a test called an anti-tiisue transglutaminase and you may need a colonoscopy to diagnose to problem correctly. ...Read more

15

15
Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?

You had mono...: Your mono-like symptoms likely prompted the testing- i hope you are starting to feel a little better. Testing for different antibodies (igm and igg) against ebv, requires careful interpretation. In early phases of infection, the igm level peaks first followed by a decline; levels of igg peak afterwards, and may remain elevated for quite a while. ...Read more

16

16
Positive for thyroid paroxidase antibodies and thyroglobulin antibodies. What does this mean? Had pap thyroid cancer in 2008 with thyroidectomy

Immunity to thyroid: The thyroid makes thyroglobulin (tg) and thyroid peroxidase (tpo). Even though you had your thyroid removed, your body's immune system sees tg and tpo as foreign and has made antibodies to them. This means that following your tg as a way to monitor your thyroid cancer might be unreliable. It could also mean you have thyroid tissue that is still present in your body. Ask your endocrinologist! ...Read more

17

17
Thyroid swelling. Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test-normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?

Thyroid swelling. Ultrasound heterogenous thyroid parynchema with hypervascularity. Blood test-normal tsh t4 t3 (liothyronine) etc but >1300 TPo antibodies?

Hard to say: Ive yet to have anyone NOT have elevated TPo but I havent sent many. The standard answer would be that it likley is GRAVES disease starting but if there arent a lot of symptoms and the labs are normal you wouldnt give treatment. Retesting if symptoms and at about every 3 months. ...Read more

See 1 more doctor answer
19

19
Discuss monoclonal antibody production?

Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

20

20
downs,systemic rheumatoid arthritis, anemia tsh t4 normal has thyriod antibodies hyperthyroid why

  downs,systemic rheumatoid arthritis, anemia tsh t4 normal has thyriod antibodies hyperthyroid why

Autoimmune disorders: like Rheumatoid Arthritis, diabetes & thyroiditis have an ^ed incidence in children with Down Syndrome (DS). A normal Free T4 & ^ed Ultrasensitive TSH indicates sub-clinical HYPOthyroidism that can become clinical. Macrocytosis, large RBC's, in infants with DS remains lifelong in 2/3rds. It can be associated with anemia from low Vitamin B12 & Folate (folic acid) or iron levels, hypothyroidism or leukemia. ...Read more

See 1 more doctor answer
Dr. Brendan Stack Jr.
236 doctors shared insights

Thyroglobulin (Definition)

A protein found in the thyroid gland and circulating in the bloodstream that binds to thyroid hormone to allow the hormone to travel throughout the body to its target sites without getting damaged or acting ...Read more


Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more