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Doctor insights on: Thyroglobulin Antibodies

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Dr. Peter Ihle
27 doctors shared insights

Thyroglobulin Antibodies (Overview)

Thyroglobulin antibodies are proteins made by the immune system. The immune system is recognizing the thyroid as strange to the body. Thus, this is a marker of autoimmune thyroid disease. It is usually measured to confirm hashimoto's thyroiditis, but can be seen in people without significant thyroid pathology and with normal thyroid levels. It can also be seen with any autoimmune thyroid disease.


Dr. Peter Ihle
27 doctors shared insights

Thyroglobulin Antibodies (Overview)

Thyroglobulin antibodies are proteins made by the immune system. The immune system is recognizing the thyroid as strange to the body. Thus, this is a marker of autoimmune thyroid disease. It is usually measured to confirm hashimoto's thyroiditis, but can be seen in people without significant thyroid pathology and with normal thyroid levels. It can also be seen with any autoimmune thyroid disease.


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If your anti thyroglobulin antibody says <20, what does that mean?

Normal result: Negative result for this antibody is normal. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm. ...Read more

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Tt papillary cancer and hurtle cell. Recent blood work TSH .59 total T3 (liothyronine) 64.7. Free T4 1.5. Thyroglobulin antibodies 1.5 what does that mean?

Tt papillary cancer and hurtle cell. Recent blood work TSH .59  total T3 (liothyronine) 64.7. Free T4 1.5. Thyroglobulin antibodies 1.5 what does that mean?

Thyroid cancer: Your dose of synthroid (thyroxine) should be adjusted such that your TSH is suppressed, and yours is about right, although your endocrinologist may increase your dose slightly. Thyroglobulin is a marker of recurrent cancer, but thyroglobulin antibodies can interfere with the assay. This is complicated. You need to discuss all of this with your endocrinologist. ...Read more

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Read this on my lab report "low positive thyroglobulin antibodies are seen in assymptomatic population" what does that mean in real terms?

Read this on my lab report "low positive thyroglobulin antibodies are seen in assymptomatic population" 
what does that mean in real terms?

Not diagnostic: In general, lab tests are used to support a clinical diagnosis and thus a positive test per se does not provide a diagnosis without abnormal physical findings or symptoms. On many occasions, an abnormal lab test is not associated with any disease condition especially when the value is only slightly abnormal. If you do hundreds of tests on a healthy person, you will likely find something abnormal. ...Read more

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Negative result for thyroid peroxidase antibodies tpoab . Necessary to test my thyroglobulin antibodies tgab ?

Negative result for thyroid peroxidase antibodies  tpoab .  Necessary to test my thyroglobulin antibodies  tgab ?

Anti-thyroglobulin: Studies have shown that 99% of patients with hashimoto's thyroiditis have anti-microsomal antibodies, whereas only about 1/3rd had anti-thyroglobulin antibodies. In addition, 10-20% of persons without thyroid problems have anti-throglobulin antibodies (tg-a). These persons are likely at higher risk for future problems and should be watched more closely however, testing for tg-a is not necessary. ...Read more

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Why do I have a high thyroglobulin antibodies?

Why do I have a high thyroglobulin antibodies?

Autoimmune: High thyroglobulin antibodies indicate you have autoimmune thyroid problem. See your doctor to figure out which one. ...Read more

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Low thyroglobulin antibody <0.9 what does this mean?

NOTHING: It's as normal finding. I don't know why anyone would have drawn it in the first place. Talk w/your doctor. ...Read more

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Not well, enlarged thyroid, two benign nodules that are autonomous, TSH low, T4 low end of normal, thyroglobulin antibodies present - thoughts?

Not well, enlarged thyroid, two benign nodules that are autonomous, TSH low, T4 low end of normal, thyroglobulin antibodies present - thoughts?

Suggests autoimmune: Your symptoms and lab values suggest an autoimmune inflammatory problem. You need expert evaluation and should see a qualified doctor as soon as possible. Doctors that specialize in thyroid disorders are endocrinologists. However, many medicine doctors from family medicine and internal medicine are very adept at helping with thyroid disease. ...Read more

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Why do I have a high thyroglobulin antibodies?

Autoimmune: High thyroglobulin antibodies indicate you have autoimmune thyroid problem. See your doctor to figure out which one. ...Read more

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Dr. Bryan Haugen
230 doctors shared insights

Thyroglobulin (Definition)

A protein found in the thyroid gland and circulating in the bloodstream that binds to thyroid hormone to allow the hormone to travel throughout the body to its target sites without getting damaged or acting ...Read more


Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more