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Doctor insights on: Thymectomy For Myasthenia Gravis Treatment

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Dr. Leonid Basovich
28 doctors shared insights

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Why would a thymectomy not be done on an otherwise healthy 18 yr old suffering with generalised myasthenia gravis? Thank you for taking time to reply

Why would a thymectomy not be done on an otherwise healthy  18 yr old suffering with generalised myasthenia gravis?
Thank you for taking time to reply

Thymectomy is option: Thymectomy is a good option in the treatment of myasthenia gravis. It can result in remission of symptoms in many patients. Patients with just ocular involvement often do not need surgery, but otherwise unless there is a contraindications for surgery thymectomy would be a good option. ...Read more

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Did thymectomy so what are the chances that I have a relapse of myasthenia gravis?

Did thymectomy so what are the chances that I have a relapse of myasthenia gravis?

Generally small: Thymectomy may be curative. Generally patients may demonstrate 1. Cure, 2. Asymptomatic on medications, 3. Stable symptoms on medications and/or decreased medications. Risk factors for return of mg after surgery may be associated with presence of thymoma at time of surgery and/or incomplete thymectomy. This link may help: http://goo.Gl/3xxmd. ...Read more

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Had thymectomy. What are the chances that I could have a relapse of myasthenia gravis?

Rare: Occasionally some tiny remnants of the thymus gland remain after the surgical removal, and it is thought that these are responsible for continuing myesthenia gravis. But it is very rare. ...Read more

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Dr. Alan Ali Dr. Ali
2 doctors agreed:
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How many of you Dr's believe that Myasthenia gravis progresses/worsens over time? Would LOVE opinions please!Had thymectomy &on meds. Have had 14 yrs

Dr. Alan Ali Dr. Ali
2 doctors agreed:

Myasthenia: With treatment, you can expect normal life expectancy, except in cases of Malignant Thymoma. Thymectomy brings long-term remission. Symptoms fluctuate, but do not always get worse over time. ...Read more

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I have myasthenia gravis (had thymectomy for thymic hyperplasia). Why do I lose weight whenever i'm on prednisone?

I have myasthenia gravis (had thymectomy for thymic hyperplasia). Why do I lose weight whenever i'm on prednisone?

Good question: Usually it is the opposite. Would have to see what else is associated. Things to consider diet, other illness, over active thyroid unmasked by steroids , other medications, malabsorption. We need more information to explain this. ...Read more

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What is the treatment for myasthenia gravis?

What is the treatment for myasthenia gravis?

Multiple: About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties. Chronic and/or longterm medications may aid but can have significant adverse impact on life and/or health. In appropriate candidates, thoracic surgery to remove thymus (thymectomy) can possibly cure: http://goo.Gl/3xxmd. ...Read more

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Why is neostigmine preferred over edrophonium as a treatment for myasthenia gravis?

Why is neostigmine preferred over edrophonium as a treatment for myasthenia gravis?

Different uses: Acetylcholinesterase inhibitors are the first line of treatment due to their safety and ease of use. Pyridostigmine (Mestinon) is the usual choice. Neostigmine is available but not commonly used. Edrophonium is an acetylcholinesterase inhibitor but does not come in an oral form. It is mainly used as a diagnostic agent for MG. ...Read more

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What’s the best treatment for Double aero wat is myasthenia Gravis. Mayo Clinic Confirmed that there is no harmful antibodies (ACHR and MUSK) CT scan was normal. Mestinon was not effective and provided with Presdinosolne. Detection of MG through EMG?

What’s the best treatment for Double aero wat is myasthenia Gravis. Mayo Clinic Confirmed that there is no harmful antibodies (ACHR and MUSK) CT scan was normal. Mestinon was not effective and provided with Presdinosolne. Detection of MG through EMG?

Diagnosis: The pathophysiologic mechanism of myasthenia gravis is antibodies and thymus-derived lymphcytes directed against post-synaptic
acetylcholine receptors at neuromuscular junction. If the Mayo Clinic confirmed no antibodies then MG in question. Differential would include the following: Thyroid ophthalmopathy, oculophryngeal muscular dystrophy, Wernicke's, Cavernous sinus mass, drug,Eaton-Lambert ...Read more

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Hello doctor, I would like to know about Myasthenia Gravis symptoms trearment and if there is preventions. Thanks?

Very brief overview:: Myasthenia gravis (MG) symptoms: drooping eyelids, double vision, & sometimes trouble speaking or swallowing. Treatment: medications to suppress the immune system (steroids, cyclosporine, azathioprine). In flares/severe cases, plasmapharesis or IVIG is used. MG is an autoimmune disorder = there is no prevention. If diagnosed, there are medications to avoid, because they can make it worse. ...Read more

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What is the acoustic wave therapy influence on muscles affected by myasthenia gravis?

What is the acoustic wave therapy influence on muscles affected by myasthenia gravis?

Not sure: This doesn't sound like "conventional" therapy, but if it doesn't hurt/cost much/is harmful, then why not try? More conventional wisdom on mg can be found here: http://www.Ninds.Nih.Gov/disorders/myasthenia_gravis/detail_myasthenia_gravis.Htm. ...Read more

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Does thymectomy help in the treatment of mysthenia gravis? Give your answer in the context if there is thymus enlargement on CT scan.

Complicated: Has never been rigourously studied, and discovered coincidentally after thymoma removed in a patient with myasthenia. Sometimes, thymectomy helps a patient even if no thymoma, and if malignant thymus tumor, has to be removed and it too, may improve myasthenia. In essence, if myasthenia gravis, consider thymectomy if things are not doing well. ...Read more

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Can you have complete cure of myasthenia gravis?

Yes: Often, people may experience complete remission of mg. The thymus gland is sometimes removed which is believed to help promote complete remission in many people. Best of luck. ...Read more

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How safe is it to have a baby if I have myasthenia gravis? I know people do it, but what are the risks? Both to me and the baby? Will I have to go off my meds? Will i pass the disease on to my baby? I’d really like to have a baby, but i’m worried. My doc

How safe is it to have a baby if I have myasthenia gravis? I know people do it, but what are the risks? Both to me and the baby?  Will I have to go off my meds? Will i pass the disease on to my baby? I’d really like to have a baby, but i’m worried. My doc

The : The more common kind of myasthenia gravis is an acquired condition: your body is tricked into making antibodies that attack its own acetylcholine receptors on the surface of your muscles, reducing the ability of your nerves to activate them, and leading to weakness. There is another, much rarer type of myasthenia gravis that is not acquired, but genetic. Women with acquired myasthenia gravis won't pass the disease itself on to their children, but since the myasthnia antibodies made by mom can cross the placenta into the circulation of the fetus, the fetus can be affected temporarily (mom's antibodies can stay in the baby up to several weeks after birth). This condition is called neonatal myasthenia gravis. Newborns with neonatal myasthenia can have temporary weakness of limb muscles, breathing muscles, and feeding muscles. They can also have a condition called arthrogryposis, stiff joints with limited range of flexibility because they didn't move as much in the womb as they might have otherwise. This is why it is important to have acquired myasthenia gravis well-controlled throughout pregnancy. There are many different kinds of medications used to control myasthenia. Some of them, particularly the immunosuppressants (like methotrexate, azathioprine, mycophenolate mofetic) are known to cause harm to the baby if taken during pregancy, while breastfeeding, or even prior to conception. Other treatments such as steroids and ivig are less risky (but not zero risk). Women with myasthenia who are considering pregnancy should work very closely with a team including a neurologist experienced in the treatment of myasthenia gravis, an obstetrician and a neonatologist. This is the best way to reduce worry, and risk, as much as possible. For general information about myasthenia gravis, visit the myasthenia gravis foundation of america website at www.Myasthenia.Org. ...Read more

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Myasthenia Gravis, NOW severe osteoporosis &supposed to start Forteo shots daily! I'm scared as I DON'T want MG flare. Do u foresee any risks?

Myasthenia Gravis, NOW severe osteoporosis &supposed to start Forteo shots daily! I'm scared as I DON'T want MG flare. Do u foresee any risks?

No: Don't see any unusual risk from Forteo because of MG. It is important for you to get your osteoporosis treated since a major fracture will be devastating to someone who already has problem with muscle strength. ...Read more

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Thyroid function tests show i'm euthyroid, orbital usg is normal. Is it possibly myasthenia gravis?

Depends: There are a number of test that may confirm/deny myasthenia gravis. Acetylcholine receptor antibodies are a good start. If you are having visual issues and are concerned about myasthenia gravis, see either a neuro-ophthalmologist or neurologist. ...Read more

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Myasthenia Gravis HAVE to be on osteoporosis med. I'm severe!Interactions with Reclast (zoledronic acid) IV & MG? Scared once in system what if it flares my MG?

Myasthenia Gravis HAVE to be on osteoporosis med. I'm severe!Interactions with Reclast (zoledronic acid) IV & MG? Scared once in system what if it flares my MG?

Osteoporosis meds: One issue with some medications used in rheumatoid arthritis, is presence of anti-tumor necrosis factor action, which can make MS worse, but this mechanism does not seem salient in osteoporosis drugs, and these would be very unlikely to adversely affect Myasthenia, as Reclast (zoledronic acid) does not affect acetylcholine in any profound way. Discuss further with your doctor, but I do NOT see a problem. ...Read more

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How common is Myasthenia Gravis?

Prevalence of MG?: It's estimated that MG is present in between 50-60K individuals in the U.S. It will increase as the age of the population increases. ...Read more

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What increasesrisk for myasthenia gravis?

Wide range of people: Conditions that increase your risk for developing myasthenia include: autoimmune disease (thyroid disease, lupus, rheumatoid, type i diabetes), a tumor called a thymoma, and exposure to certain medications (most famously an immunosuppressant and chelating agent called penicillamine). ...Read more

Dr. Brian Broker
21 doctors shared insights

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