Doctor insights on:
Thymectomy For Myasthenia Gravis Treatment
Are there any new treatments for myasthenia gravis rather than the traditional cortisone and mestinon (pyridostigmine) or thymectomy?
Not really: Those are the tested ones.Get a more detailed answer ›
A pharmaceutical has been "approved by the fda. Supplements, vitamins (some exceptions) , herbals and natural products are not generally approved by teh fda as "pharmaceuticals". This does not mean they are harmless. Combinations or mixing with pharmaceuticals can be hazardous. Check with your physician or pharmacist ...Read more
Why would a thymectomy not be done on an otherwise healthy 18 yr old suffering with generalised myasthenia gravis?
Thank you for taking time to reply
Thymectomy is option: Thymectomy is a good option in the treatment of myasthenia gravis. It can result in remission of symptoms in many patients. Patients with just ocular involvement often do not need surgery, but otherwise unless there is a contraindications for surgery thymectomy would be a good option. ...Read moreSee 1 more doctor answer
Generally small: Thymectomy may be curative. Generally patients may demonstrate 1. Cure, 2. Asymptomatic on medications, 3. Stable symptoms on medications and/or decreased medications. Risk factors for return of mg after surgery may be associated with presence of thymoma at time of surgery and/or incomplete thymectomy. This link may help: http://goo.Gl/3xxmd. ...Read moreSee 1 more doctor answer
How many of you Dr's believe that Myasthenia gravis progresses/worsens over time? Would LOVE opinions please!Had thymectomy &on meds. Have had 14 yrs
I have myasthenia gravis (had thymectomy for thymic hyperplasia). Why do I lose weight whenever i'm on prednisone?
Multiple: About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties. Chronic and/or longterm medications may aid but can have significant adverse impact on life and/or health. In appropriate candidates, thoracic surgery to remove thymus (thymectomy) can possibly cure: http://goo.Gl/3xxmd. ...Read moreSee 1 more doctor answer
Different uses: Acetylcholinesterase inhibitors are the first line of treatment due to their safety and ease of use. Pyridostigmine (Mestinon) is the usual choice. Neostigmine is available but not commonly used. Edrophonium is an acetylcholinesterase inhibitor but does not come in an oral form. It is mainly used as a diagnostic agent for MG. ...Read more
What’s the best treatment for Double aero wat is myasthenia Gravis. Mayo Clinic Confirmed that there is no harmful antibodies (ACHR and MUSK) CT scan was normal. Mestinon was not effective and provided with Presdinosolne. Detection of MG through EMG?
The pathophysiologic mechanism of myasthenia gravis is antibodies and thymus-derived lymphcytes directed against post-synaptic
acetylcholine receptors at neuromuscular junction. If the Mayo Clinic confirmed no antibodies then MG in question. Differential would include the following: Thyroid ophthalmopathy, oculophryngeal muscular dystrophy, Wernicke's, Cavernous sinus mass, drug,Eaton-Lambert ...Read more
Hello doctor, I would like to know about Myasthenia Gravis symptoms trearment and if there is preventions.
Very brief overview:: Myasthenia gravis (MG) symptoms: drooping eyelids, double vision, & sometimes trouble speaking or swallowing. Treatment: medications to suppress the immune system (steroids, cyclosporine, azathioprine). In flares/severe cases, plasmapharesis or IVIG is used. MG is an autoimmune disorder = there is no prevention. If diagnosed, there are medications to avoid, because they can make it worse. ...Read moreSee 1 more doctor answer
Not sure: This doesn't sound like "conventional" therapy, but if it doesn't hurt/cost much/is harmful, then why not try? More conventional wisdom on mg can be found here: http://www.Ninds.Nih.Gov/disorders/myasthenia_gravis/detail_myasthenia_gravis.Htm. ...Read more
Does thymectomy help in the treatment of mysthenia gravis? Give your answer in the context if there is thymus enlargement on CT scan.
Complicated: Has never been rigourously studied, and discovered coincidentally after thymoma removed in a patient with myasthenia. Sometimes, thymectomy helps a patient even if no thymoma, and if malignant thymus tumor, has to be removed and it too, may improve myasthenia. In essence, if myasthenia gravis, consider thymectomy if things are not doing well. ...Read moreSee 1 more doctor answer
How safe is it to have a baby if I have myasthenia gravis? I know people do it, but what are the risks? Both to me and the baby? Will I have to go off my meds? Will i pass the disease on to my baby? I’d really like to have a baby, but i’m worried. My doc
The : The more common kind of myasthenia gravis is an acquired condition: your body is tricked into making antibodies that attack its own acetylcholine receptors on the surface of your muscles, reducing the ability of your nerves to activate them, and leading to weakness. There is another, much rarer type of myasthenia gravis that is not acquired, but genetic. Women with acquired myasthenia gravis won't pass the disease itself on to their children, but since the myasthnia antibodies made by mom can cross the placenta into the circulation of the fetus, the fetus can be affected temporarily (mom's antibodies can stay in the baby up to several weeks after birth). This condition is called neonatal myasthenia gravis. Newborns with neonatal myasthenia can have temporary weakness of limb muscles, breathing muscles, and feeding muscles. They can also have a condition called arthrogryposis, stiff joints with limited range of flexibility because they didn't move as much in the womb as they might have otherwise. This is why it is important to have acquired myasthenia gravis well-controlled throughout pregnancy. There are many different kinds of medications used to control myasthenia. Some of them, particularly the immunosuppressants (like methotrexate, azathioprine, mycophenolate mofetic) are known to cause harm to the baby if taken during pregancy, while breastfeeding, or even prior to conception. Other treatments such as steroids and ivig are less risky (but not zero risk). Women with myasthenia who are considering pregnancy should work very closely with a team including a neurologist experienced in the treatment of myasthenia gravis, an obstetrician and a neonatologist. This is the best way to reduce worry, and risk, as much as possible. For general information about myasthenia gravis, visit the myasthenia gravis foundation of america website at www.Myasthenia.Org. ...Read moreSee 1 more doctor answer
Myasthenia Gravis, NOW severe osteoporosis &supposed to start Forteo shots daily! I'm scared as I DON'T want MG flare. Do u foresee any risks?
Myasthenia Gravis HAVE to be on osteoporosis med. I'm severe!Interactions with Reclast (zoledronic acid) IV & MG? Scared once in system what if it flares my MG?
Osteoporosis meds: One issue with some medications used in rheumatoid arthritis, is presence of anti-tumor necrosis factor action, which can make MS worse, but this mechanism does not seem salient in osteoporosis drugs, and these would be very unlikely to adversely affect Myasthenia, as Reclast (zoledronic acid) does not affect acetylcholine in any profound way. Discuss further with your doctor, but I do NOT see a problem. ...Read more
Wide range of people: Conditions that increase your risk for developing myasthenia include: autoimmune disease (thyroid disease, lupus, rheumatoid, type i diabetes), a tumor called a thymoma, and exposure to certain medications (most famously an immunosuppressant and chelating agent called penicillamine). ...Read more
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