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Doctor insights on: Thrombotic Thrombocytopenic Purpura Ttp

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What is thrombotic thrombocytopenic purpura (ttp)?

What is thrombotic thrombocytopenic purpura (ttp)?

Platelet disorder.: Ttp is a blood disorder in which platelets form small clots. Formation of these clots uses up so many platelets that platelet count becomes low. The clots can get stuck in small blood vessels and cause damage to red blood cells, causing anemia. Other symptoms of ttp include fever, kidney failure, & neurologic problems. The biological cause of ttp is still uncertain. ...Read more

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Non Blanching Red Or Purple Spots (Definition)

Non blanching red or purple spots can describe purpura, which is bleeding beneath the skin that does not blanch with pressure. It can be caused by platelet disorders, coagulation disordes, vascular ...Read more


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Could someone tell me how many different kinds of Thrombotic thrombocytopenic purpura there is cause I had ttp and I thought there was just 1 kind?

Subtypes: You may have been born with low or poorly functioning ADAMTS13 (Upshaw's), or make an antibody to it, or otherwise have it inhibited, or get a TTP-like illness without a detectable inhibitor or mutation. It's good you're learning about your illness, and it's fortunate your physicians made the call. ...Read more

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What type of physician is best suited to treat thrombotic thrombocytopenic purpura?

What type of physician is best suited to treat thrombotic thrombocytopenic purpura?

TTP is managed by: A hematologist. Assistance may be needed from lab medicine or nephrology for plasma exchange therapy. Immunology, neurology and other consultants may be called in to help. ...Read more

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What is the treatment for thrombotic thrombocytopenic purpura?

What is the treatment for  thrombotic thrombocytopenic purpura?

Plasmapheresis: Ttp can be caused by a medicine, it must be stopped. The treatment can be plasmapheresis, ie blood cleansing and also treated with intravebous gammaglobulin, it still hs a highmnortality. ...Read more

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Is a splenectomy of common treatment for thrombocytopenic purpura?

Is a splenectomy of common treatment for thrombocytopenic purpura?

10% of patients: Itp is a disorder where the body forms antibodies that attach to your platelets leading to their early destruction. The greatest risk of itp is bleeding, which can occur with platelet counts below 20-30, 000. Most people will respond to medical management; if unresponsive, splenectomy is an option, with more than 2/3 of all surgical patients responsive to this treatment. ...Read more

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Does anyone here have treated idiopathic thrombocytopenic purpura? How often does it come back again?

Does anyone here have treated idiopathic thrombocytopenic purpura?  How often does it come back again?

Immune T...cytopenia: Previously called idiopathic thrombocytopenic purpura, the mechanism for isolated low platelet counts in this disorder has been elucidated as an autoimmune phenomenon and thus, it is preferably called immune thrombocytopenia. Following taper of steroids about 60-90% experience a. ...Read more

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Can idiopathic thrombocytopenic purpura cause fertility issues?

Can idiopathic thrombocytopenic purpura cause fertility issues?

Yes: Idiopathic Thrombocytopenia Purpera is an autoimmune mediate destruction of platelets due to anti-platelet antibodies. This may predispose you to disruption of successful pregnancy as result of interruption of the vascular supply to the placenta, which prevents successful pregnancy. ...Read more

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Does itp (immune thrombocytopenic purpura) weaken the immune system?

Does itp (immune thrombocytopenic purpura) weaken the immune system?

No: Itp does not supress immune system. Itp is treated commonly with immunesupressive agents such as corticosteroids, rituxan- and thse treatment would supresse immune system. ...Read more

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What is an idiopathic thrombocytopenic purpura ?

Low platelets: Idiopathic thrombocytopenic purpura (itp) is an immune-mediated problem that leads to a very low platelet count. This leads to a very high risk of bleeding. It is generally treated with immune suppressing medications such as steroids. ...Read more

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Idiopathic thrombocytopenic purpura, wha tis this?

Platelets destroyed: ITP is a bruising disease where your platelets are destroyed for an unknown reason and it causes you to bleed. This oversimplified but a complicated answer won't fit in 400 characters. ...Read more

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Has anyone lost someone to idiopathic thrombocytopenic purpura (itp)? Is it a deadly disease?

Rarely deadly: The risk of dying from a complication of idiopathic thrombocytopenic purpura (itp) is fairly low. Death, if it occurs, is usually related to a bleeding event such as bleeding in the brain. The general estimates are that the risk of death is <1%. ...Read more

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Can you get itp (idiopathic thrombocytopenic purpura) from being around a person who has it? Is it contagious?

Can you get itp (idiopathic thrombocytopenic purpura) from being around a person who has it?  Is it contagious?

Not contagious: Itp is an immune-mediated process that leads to a very low platelet count. It is not a contagious condition that you can get from being around somebody with the disorder. ...Read more

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Itp - idiopathic thrombocytopenic purpura, what is this?

ITP is just what...: It sounds like. It is characterized by bleeding, bruising (purpura) and petechiae that develop because of a low PLT count (aka thrombocytopenia), and where the specific trigger for thrombocytopenia is not known (idiopathic). We do know that in itp, the pt makes antibodies to auto-antigens found on the PLT surface (often pla-1) which mark them for destruction. This makes the PLT count low. ...Read more

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Does anyone know the reasons for idiopathic thrombocytopenic purpura?

Does anyone know the reasons for idiopathic thrombocytopenic purpura?

Autoimmune disease: Itp is an autoimmune disease and is presumed to be related to increased platelet destruction along with inhibition of platelet production via the production of specific autoantibodies. ...Read more

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Idiopathic thrombocytopenic purpura is dangerous? Can you die from it?

Idiopathic thrombocytopenic purpura is dangerous?  Can you die from it?

Rarely deadly: Idiopathic thrombocytopenic purpura (itp) can be dangerous due to a risk of bleeding. Itp causes the platelets in the blood to get very low and this raises the risk of life-threatening bleeding. However, the risk of dying from itp seems to be <1%. ...Read more

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How can idiopathic thrombocytopenic purpura disease be cured ? What medicines do you need to take?

How can idiopathic thrombocytopenic purpura disease be cured ?  What medicines do you need to take?

Can be cured: Idiopathic thrombocytopenic purpura (itp) is an immune-mediated lowering of the platelet count. Normally platelets help protect us from bleeding. The initial treatment for itp is often a steroid medication such as Prednisone but other treatments can be used. It is a curable disease but in some people it becomes a recurrent or chronic problem. ...Read more

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What's thrombocytopenic purpura?

What's thrombocytopenic purpura?

There are 2 types: Of thrombocytopenic purpura. The idiopathic type is low platelets due to immune destruction (itp). The consumption of platelets be formation of miniclots in the small vessels is called thrombotic (ttp). ...Read more

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Is thre any treatment for idiopathic thrombocytopenic purpura? Does anyone not get over it?

Is thre any treatment for idiopathic thrombocytopenic purpura?  Does anyone not get over it?

Yes there is therapy: There are many treatments for idiopathic thrombocytopenic purpura (itp). This includes steroids, immunoglobulins and also some specific medications. There can be a chronic form of itp that requires long-term therapy. ...Read more

Purpura (Definition)

Purpura are non blanching red or purple spots caused by bleeding beneath the skin. The spots do not blanch with pressure. They can be caused by platelet disorders, coagulation disordes, vascular ...Read more