Doctor insights on:
Thrombotic Thrombocytopenia Purpura In Children
Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma. ...Read more
Range of symptoms: Ttp can involve many different organs. One can have renal dysfunction, fever, altered mental status, low platelet counts and hemolytic anemia. These signs can lead to symptoms of bleeding, bruising, petechiae, confusion, anemia, fatigue, and possible jaundice among other things. ...Read moreSee 1 more doctor answer
Rare disease: This is a rare but life-threatening disease; approx 2-3 cases per 100,000 population in the USA are seen. ...Read more
TTP is a serious: Medical condition in which the platelets form clots within the small blood vessels throughout the body. Patients usually come to attention due to low HGB or platelets, but also may have fever, kidney insufficiency, seveer headache, and even seizures and stroke. This is an absolute medical emergency. ...Read more
The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange. ...Read moreSee 1 more doctor answer
Autoimmune disease: Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few platelets in the blood. Check this site: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0001562/. ...Read moreSee 1 more doctor answer
Different: Thrombocytopenic purpura (ttp) is an acute condition involving destruction of blood components including red cells and platelets and can be life threatening. Blood dyscrasia is a general term referring to a chronic or inherited blood compnent disorder such as hemophilia, leukemia, thalassemia, etc. ...Read moreSee 2 more doctor answers
High risk pregnancy: It is something that is manageable, however. You should see a perinatologist for your high risk pregnancy to make sure your baby is okay and also see a hematologist through out your pregnancy- to make sure you and baby are okay. Your hematologist will be able to help and give you the necessary treatment as indicated- like-platelet transfusion, ivig, steroid etc. ...Read more
Platelet disorder.: Ttp is a blood disorder in which platelets form small clots. Formation of these clots uses up so many platelets that platelet count becomes low. The clots can get stuck in small blood vessels and cause damage to red blood cells, causing anemia. Other symptoms of ttp include fever, kidney failure, & neurologic problems. The biological cause of ttp is still uncertain. ...Read moreSee 2 more doctor answers
I had taken mornibg after pill twice this year should I be scared? And I have thrombotic thrombocytopetic purpura.
Repeat question: Should you be scared? Of what? Is your ttp in remission? ...Read more
Could someone tell me how many different kinds of Thrombotic thrombocytopenic purpura there is cause I had ttp and I thought there was just 1 kind?
Subtypes: You may have been born with low or poorly functioning ADAMTS13 (Upshaw's), or make an antibody to it, or otherwise have it inhibited, or get a TTP-like illness without a detectable inhibitor or mutation. It's good you're learning about your illness, and it's fortunate your physicians made the call. ...Read more
I have thrombotic thrombocytopetic purpura and I want to know if its safe to take birth control pills?
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