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Doctor insights on: Thrombin Generation

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What does an elavated partial thrombin time mean?

What does an elavated partial thrombin time mean?

Coagulation test: Ptt measures intrinsic pathway of coagulation and will be prolonged if one or more of the factors are low. However, the common reason for prolonged PTT is heparin. ...Read more

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, the patient does not require to do a pro thrombin test done?

, the patient does not require to do a pro thrombin test done?

Unclear question: Coagulation tests are ordered to evaluate bleeding disorders and are routine blood tests for most hospital labs. ...Read more

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Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time. ...Read more

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What is the difference between thrombin and prothrombin?

What is the difference between thrombin and prothrombin?

Activation: Prothrombin{ II } is converted to Thrombin {IIa} ,the active form of the clotting enzyme by activated factor Xa and cofactor Va . This is the final common pathway for thrombosis. Thus Thrombin is just activated prothrombin. ...Read more

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, the patient does not require to do a pro thrombin test done?

Unclear question: Coagulation tests are ordered to evaluate bleeding disorders and are routine blood tests for most hospital labs. ...Read more

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If a partial thrombin time is high will the prothrombin also be high?

Not always: U mean: PTT vs. Pt? The partial thromboplastin time (PTT) measures the intrinsic pathway of the coagulation cascade; the protime (pt), the extrinsic. The pt is commonly affected by vitamin k antagonists (think: coumadin); the ptt, by heparin. Clotting factor deficiencies may also prolong both pt and ptt, but formal hematologist testing is required. ...Read more

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