Doctor insights on:
Anti Thrombin 3 deficiency had achy calves now getting sharp shooting pain from upper inner thigh to knee, worried if sign of another dvt?
Yes: You are at high risk of forming deep vein thrombi given your pro-thrombotic state. CAll 911 and go the nearest ER immediately for evaluation. ...Read more
Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? Factor 5 also runs in my family.
Hi- blood test shows low thrombin time - 14 while the normal rate is between 16-20- does my blood tend to clot? Thank you
Two pathway measures: The PT can be with VERY HIGH doses of heparin but generally remember our coagulation system has two primary enzymatic pathways measured differently in the lab 1. Intrinsic system :measured by aPTT (activatted partial thromboplastin time) and prolonged by heparin and 2. Extrinsic system: measured by PT (prothrombin time) and prolonged by coumadin (warfarin).They then converge at the final common pathway. ...Read more
Had a lupus test done and everything was normal except my thrombin time with a little high at 22.8 is this serious?
Are elevated tissue transglutaminase antibodies a possible reason for sneddons syndrome because of their effect on thrombin and the endothelia lining?
Bad fit: Glad you're interested in basic pathology. Not a bad conjecture. But if this were the case, sneddon's would run with gluten enteropathy. It doesn't. Under the microscope, sneddon's is a proliferative endarteritis with lymphocytes and macrophages, not what we see in antibody-antigen mediated vasculitis. ...Read more