Doctor insights on:
Thrombin Clotting Time
Prolonged: Pt, aptt and thrombin time are prolonged in most patients. ...Read more
Risk of bleeding: Bleeding time is no longer used as it is a poor predictor of bleeding risk, clotting time is too crude a test, prothrombin time tests the status of one branch of the coagulation pathway. Usually pt and PTT and platelet count are used as screening tests to assess risk of abnormal bleeding. ...Read more
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes. ?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more
Bleeding & Clotting : The tests measure different aspects of your blood homeostatic system. The bleeding time measures the ability to form a platelet plug, which is usually fast. No clot has formed yet. The clotting times measure different "arms" of your clotting cascade - times to actually form a clot, and that takes longer than the primary platelet plug i referred to previously. ...Read more
Easy way to do: Before surgery you will have preop clearance they will check all these things, will not do surgery unless these number under control. ...Read more
Plavix (clopidogrel) and afib: ACTIVE trial -Plavix (clopidogrel) +ASA(100) reduced vascular event ( stroke, MI, embolism) in AF with bleeding comparable to warfarin,but ACTIVE W trial noted warfarin was superior to ASA + Plavix (clopidogrel) in preventing vascular events. That said The AHA does not recommend adding Plavix (clopidogrel) to ASA. The first choice is warfarin followed by dabigitran, apixaban and rivaroxaban.ASA would be last. Talk to a cardiologist. ...Read more
Is a simple coagulation lab test (PT/PTT INR & Fibrinogen) sufficient to diagnose Protein C,
&/or Factor V leidmen mutation disorders?
No.: Dvt can occur while on anticoagulation and also while pregnant and on anticoagulation. If either of these occurs, it usually means that the anticoagulation has been at unacceptable levels. You need close monitoring and probably, should be followed by a hematologist. ...Read moreSee 1 more doctor answer
In Feb had prolonged PT, thrombin, and APtt not corrected w mixing study. Started pentoxyphyline tid w 325mg aspirin daily. Recent study had only prolonged thrombin. Interpretation? What is significance of continued prolonged thrombin? SLE pt.
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