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Doctor insights on: Thrombin Antithrombin Complex

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Please help! what is the difference between anti-platelets (plavix) and anti-thrombins?

Please help! what is the difference between anti-platelets (plavix) and anti-thrombins?

Clotting: Clotting involves both cells that stick together and proteins that form a mesh. Anti-platelets work on the cells. Anti-thrombins work on the proteins. ...Read more

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Please help! what is the difference between anti-platelets (plavix) and anti-thrombins?

Clotting: Clotting involves both cells that stick together and proteins that form a mesh. Anti-platelets work on the cells. Anti-thrombins work on the proteins. ...Read more

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What is the difference between thrombin and prothrombin?

What is the difference between thrombin and prothrombin?

Activation: Prothrombin{ II } is converted to Thrombin {IIa} ,the active form of the clotting enzyme by activated factor Xa and cofactor Va . This is the final common pathway for thrombosis. Thus Thrombin is just activated prothrombin. ...Read more

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What happens if heparin affects the formation of thrombin then why pt is not prolonged?

What happens if heparin affects the formation of thrombin then why pt is not prolonged?

Two pathway measures: The PT can be with VERY HIGH doses of heparin but generally remember our coagulation system has two primary enzymatic pathways measured differently in the lab 1. Intrinsic system :measured by aPTT (activatted partial thromboplastin time) and prolonged by heparin and 2. Extrinsic system: measured by PT (prothrombin time) and prolonged by coumadin (warfarin).They then converge at the final common pathway. ...Read more

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What does an elavated partial thrombin time mean?

Coagulation test: Ptt measures intrinsic pathway of coagulation and will be prolonged if one or more of the factors are low. However, the common reason for prolonged PTT is heparin. ...Read more

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, the patient does not require to do a pro thrombin test done?

, the patient does not require to do a pro thrombin test done?

Unclear question: Coagulation tests are ordered to evaluate bleeding disorders and are routine blood tests for most hospital labs. ...Read more

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If a partial thrombin time is high will the prothrombin also be high?

Not always: U mean: PTT vs. Pt? The partial thromboplastin time (PTT) measures the intrinsic pathway of the coagulation cascade; the protime (pt), the extrinsic. The pt is commonly affected by vitamin k antagonists (think: coumadin); the ptt, by heparin. Clotting factor deficiencies may also prolong both pt and ptt, but formal hematologist testing is required. ...Read more

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