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Doctor insights on: The Glucose To Insulin Ratio In Insulin Resistance

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Insulin resistance? Fasting insulin 76pmol/l after 75gOral glucose- 1hr-insulin-849pmol/l. 2 hr-864pmol/l glucose fast 5.4mmol/l 1hr10.4 2hr7.5

Insulin resistance? 
Fasting insulin 76pmol/l after 75gOral glucose- 1hr-insulin-849pmol/l. 2 hr-864pmol/l

glucose fast 5.4mmol/l
1hr10.4
2hr7.5

Time to get serious: You have normal glucose tolerance. You're fasting and 2 hr glu is not quite at the level of "impaired". Your insulin levels are on the high side, suggesting insulin resistance. Now is the time to start getting your weight under control, proper diet, and physical activity. Talk to your doctor about your particular situation. ...Read more

Dr. Michael Moran
262 doctors shared insights

Insulin Resistance Syndrome (Definition)

Insulin resistance is a state in which a given concentration of insulin produces a less-than-expected lowering of blood sugar. This results from obesity and often causes higher blood sugar levels. The early stage of Insulin resistance, known as impaired fasting glucose (IFG) or prediabetes, is potentially reversible with significant weight loss (at least 7 percent). However, without weight loss, Type 2 Diabetes generally results, often causing severe damage to arteries and ...Read more


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If you have normal glucose levels, is it still possible for you to be insulin resistance?

If you have normal glucose levels, is it still possible for you to be insulin resistance?

Yes: In early stages, body makes more insulin to keep glucose under check but tissues, especially muscles may be resistant to insulin. You can improve your insulin sensitivity by exercise. ...Read more

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I recently was told that I had high insulin resistance and low fasting glucose levels. What does this mean?

I recently was told that I had high insulin resistance and low fasting glucose levels. What does this mean?

Pre diabetes: Insulin resistance is the precursor to type 2 diabetes. It is estimated that people who eventually develop diabetes have had Insulin resistance for at least 10-15 yrs beforehand. Obesity, high blood pressure, high triglycerides, low HDL cholesterol, and high fasting glucose are indicators of Insulin resistance (if you have at least 3 out of 5). Weight loss and exercise are essential for treating. ...Read more

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How likely is it that I have insulin resistance, if my random blood glucose levels are normal?

How likely is it that I have insulin resistance, if my random blood glucose levels are normal?

Varies: The answer depends on many things, including what risk factors you currently have (obesity, metabolic syndrome, family history of diabetes...) just because you have a normal random blood sugar does not rule out Insulin resistance. Your body might keep your bs normal at the expense of very high level of Insulin in early diabetes. You need to measure glucose, Insulin and c-peptide level as a start. ...Read more

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Glucose fasting 80, 60min 168, 120min 119. Insulin fasting 5.25, 60min 42.36, 120min 34.47. HbA1c 5,2%. Impaired glucose tolerance/insulin resistance?

Glucose fasting 80, 60min 168, 120min 119. Insulin fasting 5.25, 60min 42.36, 120min 34.47. HbA1c 5,2%. Impaired glucose tolerance/insulin resistance?

Nice and normal: Hi. Those glucose and insulin values look nice and normal, showing neither impaired glucose tolerance nor insulin resistance. Eat healthily and exercise regularly. Good luck! ...Read more

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Is it possible to have pcos without insulin resistance on the c-peptide exam (did twice) and glucose levels are always around 84-85.

Wrong test: C-peptide is not a test for Insulin resistance. It is a test to see if you are still making your own insulin, which we knew that you were or else you would have had type 1 diabetes. There is not specific lab test for Insulin resistance, it is an accumulation of other information and findings by your doctor. Insulin resistance with a normal glucose should yield an elevated c-peptide. ...Read more

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I am a 38-year-old woman with pcos with insulin resistance and impaired glucose tolerance in 2005 I have been take metformin since then I've lost 70 po?

I am a 38-year-old woman with pcos with insulin resistance and impaired glucose tolerance in 2005 I have been take metformin since then I've lost 70 po?

Good job: If you have lost 70# you are doing very well. Weight loss has been shown to improve both pcos and Insulin resistance. Check with your doctor — it is possible your Insulin resistance has improved enough you can decrease the dose of metformin. ...Read more

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Should a prediabetic use glucose meter to monitor glucose after meals to learn which foods cause hi blood sugar to avoid further insulin resistance?

Should a prediabetic use glucose meter to monitor glucose after meals to learn which foods cause hi blood sugar to avoid further insulin resistance?

Maybe but it depends: While your suggestion is not currently part of ada guidelines & recommendations, if it will help you see result of your food choices & help you make better choices, then I think it's reasonable. In truth, your nutritionist can help you develop healthy eating habits w/o using a glucometer. For instance, check out the mediterranean diet. Don't forget to exercise regularly to reduce Insulin resistanc. ...Read more

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Consistently high LH level, always high lh:fsh ratio, last result showed 14.4 LH to 6.6 fsh. Do I have insulin resistance or hyperinsulinemia?

Consistently high LH level, always high lh:fsh ratio, last result showed 14.4 LH to 6.6 fsh. Do I have insulin resistance or hyperinsulinemia?

Maybe (not) . . .: Can't tell anything about Insulin resistance or hyperinsulinemia by measuring your lh & fsh. When you're young & menstruating, your lh & fsh will vary throughout your cycle. Once you go thru menopause, your lh & fsh remain elevated. If you want to determine if you're resistant to Insulin or have high Insulin levels, just measure fasting insulin. ...Read more

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Concerned. My fasting glucose test came back negative bt I have POCS, am thin & have symptoms of type 2 diabetes can I still have insulin resistance?

Insulin resistance. : Glucose N in thin PCOS. Asks could I have insulin resistance. ANS: yes but not likely and detailed testing for IR rarely done in practice. Keep up the good work. ...Read more

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Women: insulin resistance--what is that?

Women: insulin resistance--what is that?

Diet, nutrition: When we consume too many high glycemic foods too much Insulin is released into the blood stream. This eventually leads to Insulin resistance, metabolic syndrome and weight gain. The type 2 diabetes epidemic is a direct result of this. Most people do not understand that diet foods and drinks and sugar free products are loaded with artificial sweeteners which are much more of a problem! ...Read more

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Is insulin resistance reversible? If so, how?

YES!: Yes, but it is under your control. Drastically change your diet to minimize any processed foods, avoid gluten and dairy. Exercise often — both aerobic activity and strengthening such as yoga.
Good luck! ...Read more

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Are there any ways to reverse insulin resistance?

Are there any ways to reverse insulin resistance?

Yes: Weight reduction, some medications help with Insulin resistance (actos, metformin), correction of exacerbating factors — thyroid disorder, adrenal dysfunction. For most people the key is weight reduction. ...Read more

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Could I have insulin resistance but be non diabetic?

Could I have insulin resistance but be non diabetic?

Yes : Insulin Resistance increses your risk of developing Diabetes and some may call it a Prediabetic stage
So if you treat Insulin resitance with proper nutrition. Exercise, weight loss if obese or over weight, and Metformin if prescribed by your doctor, not smoking and keeping BP under control.
You can defer onset of full-blown Diabetes ...Read more

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What are the chances and signs of having hypoglycemia if you are insulin resistance?

Not likely: If you have Insulin resistnce, you are more likely to have hyperglycemia, or high blood sugar. The symptoms would be frequent urination, fatigue, sweating, numbness in feet, blurred vision.
Hypoglycemia would also be sweating, lightheadedness, hunger. ...Read more

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Are sebaceous cysts and insulin resistance connected/?

Are sebaceous cysts and insulin resistance connected/?

Not directly: There is no direct connection between those two problems. Although an occult infection (in a sebaceous cyst) can cause your blood glucose to be persistently elevated. ...Read more

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Could you tell me what are effects of insulin resistance in pcos?

Could you tell me what are effects of insulin resistance in pcos?

Most have it!: Insulin resistance is a cause for pcos. Most women with Insulin resistant pcos also have hirsutism (extra facial hair/body hair). The long term consequence is the development of type 2 diabetes. It is part of at broader issue: metabolic syndrome. Insulin is both anabolic, but also inflammatory. Eating much less starch and sugar is key. Treatment with metformin will help. ...Read more

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What is insulin resistance?

High insulin: Insulin resistance is a state in which a given concentration of Insulin produces a less-than-expected lowering of blood sugar or that a supra physiological level of Insulin is needed to maintain bs. In many scenarios, ir poses a significant risk factor for developing fatty liver and diabetes. ...Read more

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What's insulin resistance pl.

What's insulin resistance pl.

Insulin resistance: Is a disorder in which the pancreas is making insulin, but the insulin does not work correctly (the body is resistant to the effect of insulin). As a result, the pancreas makes more insulin to compensate, in order to keep the blood sugar normal. This can eventually lead to diabetes, polycystic ovarian syndrome, hypertension, high triglycerides, low HDL cholesterol, and weight gain. ...Read more

Tolerance (Definition)

When one takes a drug, such as heroin or alcohol, repeatedly, 'tolerance' develops because more of the drug is needed to give the same effect on the body/brain; e.g. Liver enzymes r stimulated to metabolize the drug faster and faster. There may be a strong genetic predisposition to addiction, some studies suggesting that 1 of 10 people will become dependent on alcohol or some ...Read more


Blood Sugar (Definition)

The blood sugar concentration or blood glucose level is the amount of glucose (sugar) present in the blood of a human or animal. The body naturally tightly regulates blood glucose levels as a part of metabolic homeostasis. Glucose is the primary source of energy for the body's cells, and blood lipids (in the form of fats and oils) are primarily ...Read more