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Doctor insights on: The Best Antidepressants For Irritability

Time to talk with MD: Four simultaneous psychiatric medications may introduce additional possibilities of interactions although in some instances patients require several medications to control their symptoms and behaviors. Talk to your doctor and consider referral to a psychiatric provider if you already do not have access to one. ...Read more

Relapse? Detox?: There are many thing which may be going on. You do not say what you started on it for. If depression the irritability may be a return to your depressive symptoms. Some people who are just getting off the med may get similar symptoms without it being relapse. If by next week you feel down mood may need to get back on it. Consult your MD ...Read more

Gut has serotonin: Common antidepressants (ssris like prozac) act on serotonin and the gut has more serotonin than the brain. ...Read more

Antidepressants: And other medications can loose their effectiveness over time. Please visit your doctor. He/she MAY change the med you are taking or adjust the dosage. See "Feeling Good" a book by David Burns to learn some strategies to mange anxiety & depression and thus empower yourself. Peace and good health. ...Read more

Please get more help: Postpartum is a very vulnerable phase. Mental health problems that emerge or worsen here can have serious consequences, if not treated effectively and expeditiously. Make sure you are in the hands of an expert psychiatrist, not just your obstetrician. Keep your dr apprised of problems - don't wait to go back or to provide updates to the dr if you are not improving. More can be done for you. ...Read more

Partly controlled: depression, regulate ur meds with ur psych ...Read more

None: Depression and being overweight go hand in hand but antidepressant is not the answer. The problem is in your relationship with food and at our institute we search for the root cause and start with treatment there, as well as initiating weight loss and detox. To solve the weight problem is work, but done properly it can be solved long term. ...Read more

There is no one best: Antidepressant. Cymbalta (duloxetine) is great if your have pain too. Wellbutrin is superb for atypical depression. The ssri 's are good for anxiety and classical depression. Etc. Medications can be chosen for their side effect profiles as well as their niche benefits. ...Read more

Doesn't matter: If you're taking the right amount of synthroid (thyroxine) replacement, it doesn't matter. It's the same as if your thyroid was normal. ...Read more

No "best": Each person responds differently and even what works for awhile might need to be switched. Part of this is actually placebo, you activating your own optimism and hope. Another part is the novelty of internal chemical experience disrupting the depressed patterns. Without life changes you can learn in talk therapy the old rut can return. So go for safest drug and make good life decisions. Best! ...Read more

Eagle syndrome: Lyrica (pregabalin) can ease symptom of pain, but the treatment for this syndrome is surgery. ...Read more

It is best to taper: Off the prozac (fluoxetine) under the supervision of your physician/ psychiatrist. ...Read more

Weight loss: The bottom line is that calories expended must exceed calories consummed. Recommend at least 5 servings of vegetables & 4 servings of fruit per day. Hydrate well. Try to get in physical activity daily. Working with a nutritionist or with a comercial weight loss program can be of help. ...Read more

SSRI: But about 4 percent might get worse and experience suicidal ideation, therefore, must be watched closely. ...Read more

With your Docs help!: Ideally this should be done in conjunction with the prescribing physician. Stopping an antidepressant on your own is not a good idea. Most antidepressants will clear from your system within five days. Certain antidepressants such as fluoxetine (prozac) can actually take a full month to clear however. ...Read more

It depends: In head to head studies, antidepressants generally work equally well. The choice of antidepressant really depends on the side effects that the person may have or be willing to tolerate. In ocd, most doctors use either fluvoxamine or clomipramine because they work the strongest on serotonin receptors. But other antidepressants have been known to help too. ...Read more

Best Antidepressant: No best antidepressant exists. Different people respond differently thru trial & error, mostly guided by tolerability & side-effect profiles of the medicines, history of prior response, & family history of response to similar medications. ...Read more

SNRI: The serotonin norepinephrine reuptake inhibitors (SNRI) Cymbalta and Savella (milnacipran) are possible options. Ask your doctor if one of these would be right for you. ...Read more

Can be a good choice: Cymbalta (duloxetine) is approved for treating pain and it is also an effective anti-depressant. The pain pathways are intimately entwined with the emotional centers of the brain and seratonin is a neurotransmitter involved in both mood and pain. Your symptoms besides just pain will determine which anti-depressant the doctor picks. ...Read more

A known unknown: We know the atd initial actions, but the brain transmitters and circuitry adapt in a complex manner. Some people relapse, some do fine when they stop. But the risk of relapse is higher than those who continue. Be very careful stopping if you have history of suicidal tendencies. ...Read more

Equal: On face value most SSRIs are equivalent to each other. Specific recommendations depend on other medicines you take, your reaction, any side effects you might have and your genetic drug metabolizing enzymes. Fluoxetine also known as Prozac (fluoxetine) was the first SSRI and has a long half life so can be taken once per week but otherwise all at pretty similar. ...Read more

Lexapro (escitalopram) 10mg in am: Good class of medications to start are SSRIs. From that class Lexapro (escitalopram) or celexa (citalopram) if your insurance does not cover the more expensive Lexapro. Starting doses are for Lexapro 10mg usually in the morning and 20mg for celexa, also in the morning. ...Read more

SSRIs: Antidepressants called SSRIs (selective serotonin reuptake inhibitors) like fluoxetine, sertraline, citalopram or escitalopram can alleviate a lot of the symptoms of PTSD. They especially help with the anxiety, moodiness and irritability. Certain blood pressure medications, like clonidine and prazosin can help with insomnia and nightmares. However, therapy is always first and best for PTSD. ...Read more

Ssri or tca for ocd: Generally ssri's are the Rx of choice for OCD. The so-called "gold standard" is a tricyclic antidepressant called clomipramine (brand 'Anafranil') which can also be used, though could have more side effects and involve a blood level. Best wishes! ...Read more

Therapy?: Have you yet tried any form of psychotherapy? Typically, the optimal combination of things to treat emotional issues such as anxiety or depression, which are common is medication (which, on your best day, is supposed to take the edge off symptoms) but the real gruntwork takes place in psychotherapist's consulting room. ...Read more

Maybe: Remeron causes alot of sedation and weight gain be carefull, safer might try benadryl 25 mg 3x/.day but others like old prozac might work, more addictive types are benzodiazapines like valium and antipsychotics like serpoquil, see a psychiatrist, find root of problem, if no religion try Jesus thru the catholic faith, always works for me, praying to Jesus, the original or whatever you choose ...Read more

There is none.: There is no one size fits all. There is no best one because there are a lot of factors to consider. There may be a best one for you but the only way to know is for you to discuss it with your doctor to talk about the risks and benefits of each. Although they do similar things, they are different and have differing side effect profiles. ...Read more

Depakote: Depakote is often used to stabilize mood in someone with bipolar disorder. If possible, no antidepressant at all is used, because these can precipitate mania. Some bipolar patients do need additional antidepressants, but your own doctor who knows your case is the best resource to discuss this with you. Depending on how much anxiety you also have, possibly wellbutrin (bupropion) or Celexa are choices. ...Read more

Everyone unique: Ssris usually a few require maois--find a doc who treats pd & work with him or her--if someone in your family has pd & is doing well on a drug it will likely work for ypu. ...Read more

Wellbutrin (bupropion): Best to talk to your doctor about what medication might be best for you and the symptoms you might be having. That said, Wellbutrin (bupropion) XL is activating and has been shown to decrease weight in certain patients with depression. However, some patients gain weight with this medication as well. .. It's more of an individual response than a hard/fast rule. Hope that helps! ...Read more