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Doctor insights on: The Affected Chromosome Of Celiac Disease

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Dr. John Chiu
639 doctors shared insights

Celiac Disease (Definition)

A disease caused by an immune system reaction to eating gluten, a protein found in ...Read more


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Can there be epigenetic involvement in the pathogenesis of celiac's disease?

Can there be epigenetic involvement in the pathogenesis of celiac's disease?

Nearly all: Epigenetic is considered a crucial step in health and disease and thus the reason why that only a minority of the people with the same genes develop celiac disease. ...Read more

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The disease of white skin is genetically inherited?

The disease of white skin is genetically inherited?

Vitiligo: If you are referring to vitiligo, as far as i know, the current thinking is that it is related to genetic defect in the immune system, but if you are asking if it can be passed down from a parent, I have never seen or heard of this. ...Read more

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Is pku and huntington disease the same disease entity?

Is pku and huntington disease the same disease entity?

Some comments: Pku is a problem with children and this needs early diagnosis to prevent profound complications. Huntington's chorea is an autosomal dominant disorder occurring later in life, and is relatively rare, but genetic counseling might be valuable. Neither disorder has any relationship to the other. ...Read more

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Does autosomal recessive polycystic kidney disease of one parent could be genetically transmissible to one of the children and what is the percentage?

Does autosomal recessive polycystic kidney disease of one parent could be genetically transmissible to one of the children and what is the percentage?

ARPKD: Autosomal recessive kidney disease will transmit to a child from a parent who has ARPKD only if both parents carry the trait. Percentage is low. ...Read more

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What part of the nervousesystem is affected by Lyme disease?

What part of the nervousesystem is affected by Lyme disease?

Numerous parts: peripheral nerves and different parts of the brain can be involved. ...Read more

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What is involved in celiac disease screening?

What is involved in celiac disease screening?

Bloodwork: Celiac disease is usually screened for (in the right patient) with blood tests. Depending on the results of these blood tests, you may be referred to a gastroenterologist to get a biopsy to confirm the diagnosis. You have to be on a regular diet (not gluten-free!) for these tests to be valid. ...Read more

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What are the tests of the disorder "huntingtons disease or hungtingtons chorea" ?

What are the tests of the disorder "huntingtons disease or hungtingtons chorea" ?

Genetic test: Huntington's disease is due to an autosomal dominant mutation of the huntintin gene. The most definitive diagnosis of this disease is a positive test for this mutation. This genetic testing can be done before symptoms develop, but early diagnosis does not affect the outcome of the disease. Genetic counseling is recommended before testing. ...Read more

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What is the manifestation of wilson's disease in female?

What is the manifestation of wilson's disease in female?

Same as in male: Miss it, and the person becomes unable to move normally, then paralyzed. The liver develops cirrhosis and ultimately fails. There's moderate hemolysis and often a Fanconi syndrome of the proximal tubule. ...Read more

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Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

not true: Cystic fibrosis is a metabolic disorder more common in caucasions by present in many populations.The incidence is 1/3500 caucasion, 1/17, 000 african american, 1/80, 000 native american. It arises in mutations in the cftr gene that regulates cellular transport of chloride.There are in excess of 700 known mutations recorded but most common is the delta 508. ...Read more

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Which is the rate of occurrence of sickle cell disease( gene frequency, and mutation rate)?

Depends on geography: Given the single base change responsible for sickle cell trait in the beta globin gene, the frequency of new mutations is essentially zero. According to the cdc in the usa, 8-10% of african americans have sickle cell trait and 0.2% have sickle cell disease. Conversely, in western africa, the prevalence of sickle cell trait is 30-40%. ...Read more

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Which type of genetic liver disease can cause the same symptoms as shaken baby syndrom?

Which type of genetic liver disease can cause the same symptoms as shaken baby syndrom?

None: I have never heard of a liver disease, which gives the same symptoms as "shaken baby" syndrome. ...Read more

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Does the age of a child affect the severity of kawasaki disease?

Does the age of a child affect the severity of kawasaki disease?

Possibly: Kawasaki disease has an unknown cause. It can actually cause a "heart attack" in some kids. I had several cases of the disease and one boy had an abnormal ekg. I found that the disease quickly disappeared when i treated these kids with a very high powered organic vitamin. I passed this information on to a professor of pediatrics at a university. He thought that i was crazy! ...Read more

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What kind of mutation occurs in scid disease?

What kind of mutation occurs in scid disease?

Depends: There are too many different types of scid - severe combined immunodeficiency for there to be just one mutation. Scid is commonly referred to as "bubble boy" disease in the lay press. The most common type is linked to the x chromosome and causes a defect in t cells and natural killer cells. ...Read more

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Huntington's disease, an often fatal disease of the central nervous system, is inherited from a dominant alle, is this right?

Huntington's disease, an often fatal disease of the central nervous system, is inherited from a dominant alle, is this right?

Yes: Autosomal dominant disorder with the presence of excess numbers of tri-nucleotide repeats within the Huntington's gene on human chromosome 4. ...Read more