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Doctor insights on: Thalassemia Disease

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Could one prevent beta thalassemia disease?

Could one prevent beta thalassemia disease?

Yes: Beta thalassemia disease is prevented if beta thal carriers do not have children with one another (if they have children together, some children will be normal, some carriers, and some have disease). The other, less desirable way, is to test fetuses during pregnancy and abort the fetuses who have beta thal major. ...Read more

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Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more


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What is the difference among sickle cell disease, animea & thalassemia?

What is the difference among sickle cell disease, animea & thalassemia?

Different genes: Anemia is a deficiency of red blood cells/hemoglobin in the blood. Sickle cell disease and thalassemia are both genetic diseases that affect hemoglobin production and result in anemia. There is more than one type of thalassemia. ...Read more

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Why is it that alpha and beta -thalassemias result in more clinically severe diseases than other types of thalassemia?

Used for blood cells: Alpha globulin (made by the Alpha genes) and beta globulin (made by the beta genes) are the 2 globulin molecules needed to make normal adult hemoglobin (the red stuff in normal red blood cells). Mutations that prevent Alpha and beta globulin production will cause severe symptoms, but other mutations may not be as noticeable if the proteins the other genes make are not as crucial to life. ...Read more

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Is hb e beta thalassemia cureble? Is it a trait or disease?

Genetic disorder: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3237252/ "the disorder is characterized by marked clinical variability, ranging from a mild and asymptomatic anaemia to a life-threatening disorder requiring transfusions from infancy. "...."careful tailoring of treatment is required for each patient, and that therapeutic approaches should be re-assessed over-time." not curable..Look at website-. ...Read more

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If one parent has hb e beta thalassemia and the other is normal, is their child can get disease?

If one parent has hb e beta thalassemia and the other is normal, is their child can get disease?

No: The normal parent will give his or her normal gene to their baby. That means the baby will have one abnormal and one normal gene, meaning the baby would be a "carrier" of one bad gene and not suffer the actual disease. The only way the baby would end up with 2 abnormal genes is if the gene from the normal parent got altered by a new mutation... Which is unlikely to happen. ...Read more

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After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

9-12 months old: Children with beta-thalassemia major usually demonstrate no initial symptoms until the later part of the first year of life (when beta chains are needed to pair with Alpha chains to form hemoglobin (hb) a, after gamma chains production is turned off). ...Read more