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Doctor insights on: Thalassemia Causes Leukemia

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Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

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Dr. Liawaty Ho
1,098 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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How are beta-thalassemia and leukemia related?

How are beta-thalassemia and leukemia related?

Unrelated: Beta thal is a congenital disease-where there is defect on the beta- globin inside the rbc. The severity of the disease depends on how many b- globin affected. Beta thal major is very debilitating- tansfusion dependent and only transplant can perhaps cure it. Leukemia however is malignancy of the progenitors of the white cells-in bone marrow. Different types of leukemia-acute vs chronic leukemia. ...Read more

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What causes leukemia?

What causes leukemia?

Leukemia cause: We don't know for sure. Leukemia develops as the consequence of a series of genetic changes in blood cell offsprings. These changes alter normal growth and differentiation of the cells, resulting in an accumulation of abnormal, immature blood cells in the bone marrow and peripheral blood. Exposure to chemicals, radiation, tobacco, or chemotherapy, infection, etc have been associated with leukemia. ...Read more

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Does leukemia usually cause many symptoms?

Does leukemia usually cause many symptoms?

Varies: Acute leukemias usually cause symptoms that bring a patient in to a doctor or emergency room. Chronic leukemias are often found incidentally when a blood count is ordered and abnormalities are identified. ...Read more

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What are the main causes of leukemia?

What are the main causes of leukemia?

Random mutations...: occur in our body's cells because they are not able to correct all of the millions of DNA damage events that naturally occur during our life. In the event that a bone marrow progenitor cell gets hit with an unlucky series of mutations then a leukemic cell will be made, and grow out of control. Familial susceptibility, or exposures (e.g. chemotherapy, radiation, or benzene) may increase this risk. ...Read more

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In what way can chemicals cause leukemia?

In what way can chemicals cause leukemia?

See below...: Exposure to certain chemicals like benzene or formaldehyde may increase the risk for cancer including leukemia. This is probably due to the mutagenic effect of these agents, meaning they can induce mutations in otherwise normal cells resulting in abnormal cells that can become cancerous; however, the process is usually multifactorial and other conditions need to be met to develop cancer. ...Read more

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What external chemicals can cause leukemia and where are they found?

Benzene products: Benzene used in petrochemical industry is one know cancer causing agent. But most cases of leukemia come out of the blue, without any obvious or known cause. It is more of an accident of nature. I doubt you will be able to lay a finger on the cause of your leukemia. ...Read more

Dr. Michael Engel
261 doctors shared insights

Thalassemia (Definition)

Thalassemia is a genetic condition in which the oxygen carrying hemoglobin molecule is altered by genetic mutations. This leads to symptoms of anemia include fatigue, pallor, ...Read more