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Doctor insights on: Thalassemia Causes Leukemia

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Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

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Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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How are beta-thalassemia and leukemia related?

How are beta-thalassemia and leukemia related?

Unrelated: Beta thal is a congenital disease-where there is defect on the beta- globin inside the rbc. The severity of the disease depends on how many b- globin affected. Beta thal major is very debilitating- tansfusion dependent and only transplant can perhaps cure it. Leukemia however is malignancy of the progenitors of the white cells-in bone marrow. Different types of leukemia-acute vs chronic leukemia. ...Read more

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What are the main causes of leukemia?

What are the main causes of leukemia?

Random mutations...: occur in our body's cells because they are not able to correct all of the millions of DNA damage events that naturally occur during our life. In the event that a bone marrow progenitor cell gets hit with an unlucky series of mutations then a leukemic cell will be made, and grow out of control. Familial susceptibility, or exposures (e.g. chemotherapy, radiation, or benzene) may increase this risk. ...Read more

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What are the causes of leukemia in children?

What are the causes of leukemia in children?

Unknown: Most leukemias in adults and children do not have a specific etiology. Some leukemias in children can be linked to genetic abnormalities like down's syndrome, neurofibromatosis, bloom syndrome, and others. Ethnicity may play a role in all, hispanic children tend to have higer risk. High birth weight has been associated with higher risk though really this is unclear. Other factors are inconsistent. ...Read more

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Which forms of leukemia are caused by a mutation?

Which forms of leukemia are caused by a mutation?

Most are due to muta: Mutations are common in all cancers. In Leukemia the very first mutation(Single mutation, causing cancer was discovered in Chronic Myelocytic Leukemia(CML). In most other Leukemias, there are multiple mutations present once we have learned how to search for them by Genomic profiling. ...Read more

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I want to know what's the main cause of childhood leukemia?

Unknown: Just like most other cancers, the cause of leukemia is unknown. ...Read more

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Does gcsf injections 2 a week for 2 1/2 years cause leukemia?

Probably not.: Gcsf is given to raise the neutrophil count. Long term use usually is for severe chronic neutropenia with high risk of infection. While gcsf use has been reported in patients who have subsequently developed leukemia, so far such reports are only in people whose underlying disease already confers such a risk. There is no convincing evidence that gcsf increases that risk. ...Read more

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Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more