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Doctor insights on: Testing Positive For Ana

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Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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After testing I have ANA positive and rnp positive (1.4). What could this mean? ?

After testing I have ANA  positive and rnp positive (1.4). What could this mean? ?

Context: If the titers are both 1:4 and you do not have obvious lupus or mixed connective tissue disease, then i'd bet they mean little or nothing. Diagnosis in rheumatology is based on history and physical exam, with labs just for confirmation. ...Read more

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I tested positive ANA and anti dsdna, later testing neg. I have past diagnosis that may apply to lupus but do not do well articuliatng at dr. Help?

I tested positive ANA and anti dsdna, later testing neg.  I have past diagnosis that may apply to lupus but do not do well articuliatng at dr.  Help?

Tests and lupus: The question is why is the doctor running the tests? If your symptoms and physical signs are a strong indication of possible lupus, positive dsdna helps confirm a diagnosis of lupus. If the tests are run for "screening", they are worthless tests. No diagnosis of lupus or connective tissue disease can be made on antibody studies alone. ...Read more

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Can birth control cause false positive ANA and dsdna using mia testing method? How reliable is this testing method?

Not necessarily: It is pretty unlikely that could be causing those tests to be positive. It does occur on occasion however but i would look for other issues. It could be false-positive. ...Read more

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I have joint pain and fatigue. My edno did testing. What do these test results mean? R factor 7, ANA choice- positive, rnp - 2.0, ds DNA - 5

Possibly nothing: One needs to know the titer and pattern of the ANA screen result before knowing if it has any possible significance. The rest of the tests are flatly negative. ...Read more

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My ANA test results are positive with 1:320 centromere. I have moderate fatigue and joint pain. What further antibody testing is usually suggested?

My ANA test results are positive with 1:320 centromere. I have moderate fatigue and joint pain. What further antibody testing is usually suggested?

Positive anti: Centromere antibody is highly sensitive and specific for scleroderma/crest syndrome.It could also be positive in other autoimmune conditions like sjogrens and primary biliary cirrhosis.I don't think u need more testing.Take care and god bless u! http://www.Ncbi.Nlm.Nih.Gov/m/pubmed/6384675/http://en.M.Wikipedia.Org/wiki/anti-nuclear_antibody http://www.Herbalremediesadvice.Org/autoimmune-diseases. ...Read more

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Positive ANA, 1:320, homogenous. Started testing due to high protein levels and symptoms of muscle aches, fevers, fatigue. Lupus?

Positive ANA, 1:320, homogenous. Started testing due to high protein levels and symptoms of muscle aches, fevers, fatigue. Lupus?

Not necessarily: A number of criteria have to be met to diagnose lupus. Please consult this site for more information on this topic. http://www.lupus.org/answers/entry/lupus-diagnostic-criteria For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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I have a positive ANA 1:160 Homo pattern & RNP of .3. Joint pain, limb numbness, skin indents stay for hours, bruising. No diagnosis. More testing?

I have a positive ANA 1:160 Homo pattern & RNP of .3. Joint pain, limb numbness, skin indents stay for hours, bruising. No diagnosis. More testing?

You need to: see a BOARD CERTIFIED RHEUMATOLOGIST for some further tests and a definitive diagnosis! Ask your Primary Care Provider (PCP) for a referral! Hope this helps! Dr Z ...Read more

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On a CT scan it showed moderate cortical atrophy of my kidneys,positive ANA test, nephrologist said the Sono was ok. Should I have further testing?

On a CT scan it showed moderate cortical atrophy of my kidneys,positive ANA test, nephrologist said the Sono was ok. Should I have further testing?

Is nephrologist good: If the nephrologist is good to go with the results of the tests and what needs to be done then, I would say follow his/her lead. My guess is you've done plenty of tests....time to let your doctors analyze all the tests and come up with a good plan. ...Read more

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I was tested for lupus ANA came back positive but sed rate was low could me taking 800mg motrin first have affected that?

Doubtful: The sed rate is not a totally reliable index of inflammation especially if it is down at a commercial lab. The CRP is a better index. A weak NSAID such as Motrin is unlikely to be effective. Finally the ANA is also not specific for lupus. ...Read more

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I have all the symptoms of HIV but i tested (-) for it… my dr tested me for hepatitis b, dsdna, and ld. I had a positive ANA 1.80. Any other tests?

Night sweats: You list night sweats and this is serious business. I would not fault your physician for sending you for echo to look for endocarditis. A search for tuberculosis, occult hodgkin's, and a host of other illnesses depending on your history, physical and routine labs are in order. ...Read more

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I lost 65 lbs from march to oct. Hair started falling out in june. I am ANA positive 1:640 spec pattrn. Rheum dr tested for autoimmune. All negative?

Malabsorption: This is malabsorption / maldigestion until proved otherwise. If there's joint problems too, i'm thinking enteropathy arthropathy. The ANA may be a red herring. Solving this type of problem is why we have primary care physicians; respectfully nobody here can address this beyond raising possibilities. Celiac sprue? Whipple's? Crohn's? Many possibilities. ...Read more

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I have a positive ANA and positive anti SSA RO >8 and high sed rate. Got tested for sjogrens that was negative? What other autoimmune disease could be

See details: With hair loss systemic lupus is one possibility. See a rheumatologist. If you are seeing one, ask the question to that doctor. He/she has the most specific info about your issues. ...Read more

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Tested for lupus&was ANA positive&have butterfly rash,but then tested ANA negative so my rheum says I just have fibro. Do I really not have lupus??

Tested for lupus&was ANA positive&have butterfly rash,but then tested ANA negative so my rheum says I just have fibro. Do I really not have lupus??

Lupus not just rash: The diagnosis of Systemic Lupus Erythematosus requires multiple things to be diagnosed and be happening at once within the body. It is not simply the textbook description of the butterfly or malar rash and a positive ANA. This is why medicine cannot be taught by simply making students memorize lists of symptoms and signs and patients must avoid such temptations. They are fraught with error. ...Read more

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What does a speckled ANA pattern 2 mean and what is it testing for?

What does a speckled ANA pattern 2 mean and what is it testing for?

It depends: The ANA is a screening test for lupus. However, it is very nonspecific and can be positive in numerous other conditions and even present in people without any disease. In addition, the speckled pattern is not very specific for any one disease. The ANA results should always be evaluated in context with the clinical symptoms. ...Read more

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My lab testing for primary Sjogrens (SSA, SSB) came back as NOT APPLICABLE. Is this the same as negative? The ANA test said negative. I'm confused

Not applicable: Sometimes, depending on the lab, the whole panel including SSA, SSB is not run, being conditional on a positive ANA. It sounds like this was the case in your case. Hope it helps. ...Read more

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C-ANCA, P-ANCA, ANA & CRP tests stands for what..?? Does it belongs to any cancer testing for kidneys..?? Please suggest

Vasculitis tests: The first two test for autoimmune diseases that affect your vessels. These diseases are uncommon, lethal if missed, and fairly easy to treat. ANA is a screen for some of the autoimmune illnesses, and CRP is a not-that-helpful measure of inflammation that's often misleading. These are not cancer tests. ...Read more

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Have ideopathic livedo reticularis. ANA test suggested lupus, further testing no. This was 5 yrs ago. Is there new info? What about Sneddon Syn?

Sneddon not likely: Often a family history of livedo r. and stroke if Sneddon. Antiphospholipid antibody may be positive if Sneddon, so if concerned this might be checked. Usually livedo r. cause is not found, and not associated with more severe illness. ...Read more