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Doctor insights on: Test Amyloidosis

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What blood test show Amyloidosis?

What blood test show Amyloidosis?

No blood test: There is no blood test to detect amyloidosis. Sophisticated laboratory techniques called electrophoresis or free light chain assays may reveal early evidence of some amyloid proteins. A biopsy is needed to confirm a diagnosis of amyloidosis and determine the specific type of protein involved in the disease. ...Read more

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Dr. Keith Stockerl-Goldstein
537 doctors shared insights

Amyloidosis (Definition)

Amyloid is an abnormal protein made by the body. When amyloid is deposited onto normal tissue such as skin, joints, liver, or heart, the condition is known as amyloidosis. Symptoms vary depending on the part ...Read more


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What is the diagnostic test for amyloidosis?

What is the diagnostic test for amyloidosis?

Specific test?: First: clinical. Second:confirmation and detection of monoclonal gammopathy on serum protein electrophoresis, with microscopic examination of abdominal fat, rectal or gingival biopsies looking for amyloid protein ...Read more

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What are the tests for amyloidosis?

Biopsy: Clinical suspicion and biopsy of the suspected organs, followed by examination of the tissue by a pathologist is usually needed to establish a diagnosis of amyloidosis. ...Read more

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What tests are used to diagnos primary amyloidosis?

Biopsy definitive: The evaluation will look at the history, physical, imaging, laboratory. The are extra antibodies and increased amyloid proteins in the blood. Tissue samples will show the amyloid protein. ...Read more

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Can blood tests diagnose amyloidosis?

Can blood tests diagnose amyloidosis?

No: Amyloidosis is diagnosed by tissue biopsy such as a rectal biopsy wherein the amyloid in the tissue is detected by the congo red stain. It is the accumulation of particular misfolded proteins in the space between cells (extracellular matrix) that distinguishes amyloidosis. There are many types of amyloid proteins than can cause amyloidosis. ...Read more

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I have been diagnosed with lichen amyloidosis without proper test conducted by a dermatologist at malaysia. Should i get 2nd opinion?

Easy to recognize: Lichen amyloidosis is very easy to recognize. Given that it is a chronic condition and can impact your quality of life, a second opinion wouldn't be a bad idea. ...Read more

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What is the best test to point toward (or rule out) possible al amyloidosis? Serum free light chain assays or urine free light chain assays?

Amyloidosis: They are both useful in helping physicians monitor the disease, but a tissue biopsy may be necessary to completely rule out the disease. ...Read more

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Does pathology routinely test for amyloid? Recently had thyroidectomy and have smoldering myeloma so would like amyloidosis to be ruled out.

Not routine: A special stain for amyloid is not routine for thyroid. However, amyloid can be seen on routine slides, so if there is a fair amount of it, pathologist can see something, but special stain is needed to confirm it is amyloid. important that the pathologist knows the medical history, so can be on the lookout for amyloid, which is not common and can be subtle. You can call MD and ask to make sure. ...Read more

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Testing for amyloidosis. Two 24-hr urine protein labs both showed protein 6.3mg/dl. 1st test was 140mg/24hrs from volume of 2225ml of pee. 2nd test was 129.2mg/24hrs from 2050ml pee. Both in range, but if peed more would have been over limit. Worry?

Testing for amyloidosis. Two 24-hr urine protein labs both showed protein 6.3mg/dl. 1st test was 140mg/24hrs from volume of 2225ml of pee. 2nd test was 129.2mg/24hrs from 2050ml pee. Both in range, but if peed more would have been over limit. Worry?

No worries please.: The test results take into account the concentration of protein in the urine, not just the amount. If you had consumed more fluids and made more urine, the total amount of protein would be the same even tho there was more urine. Example: if you have a cup of salt water and add more water to it, the water will be less salty but the total amount of salt will stay the same. ...Read more

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