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Doctor insights on: Tenofovir Disoproxil Fumarate Medication

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What permanent damage can a 28 day PEP course of Tenofovir (+ Fumarate + Emtricitabine) do to one's body? Also, how effective would the said combination of drugs be in preventing HIV after 68 hours?

What permanent damage can a 28 day PEP course of Tenofovir (+ Fumarate + Emtricitabine) do to one's body? Also, how effective would the said combination of drugs be in preventing HIV after 68 hours?

Damage is unlikely: It is most effective when started within 72 hours. Nausea, vomiting, and diarrhea are the most likely short-term side effects. Long-term side effects are not expected. Tenofovir may strain the kidneys or liver - usually in those with kidney disease or hepatitis already - but permanent damage is rare. The risks of long-term organ damage are much more likely from the HIV virus than from this drug ...Read more

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Dr. Sewa Legha
18 doctors shared insights

Tenofovir (Definition)

Tenofovir is a nucleoside reverse transcriptase inhibitor which is a kind of drug used for HIV (anti-viral ...Read more


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Can working out prevent my body fat from being distributed abnormally? Due to complera (emtricitabine and rilpivirine and tenofovir) medication?

Can working out prevent my body fat from being distributed abnormally? Due to complera (emtricitabine and rilpivirine and tenofovir) medication?

Complera (emtricitabine and rilpivirine and tenofovir): It would be unlikely that Complera (emtricitabine and rilpivirine and tenofovir) would cause any fat redistribution or abnormal distribution. What prompts the concern? ...Read more

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Is daily truvada (emtricitabine and tenofovir) a good preventative medication for hiv? What are my risks?

Is daily truvada (emtricitabine and tenofovir) a good preventative medication for hiv? What are my risks?

Excellent choice: Daily Truvada (emtricitabine and tenofovir) is a good idea if you are at high risk for HIV due to behaviors such as unprotected receptive anal intercourse. But Truvada (emtricitabine and tenofovir) does NOT protect you 100% from HIV. If an HIV positive partner with a high viral load ejaculates into you, there is still a chance that you can become positive. Condoms are still the best protection, and Truvada (emtricitabine and tenofovir) will not protect against other STDs. ...Read more

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If i'm negative and start taking truvada (emtricitabine and tenofovir) daily, as a preventative medication, what are my chances of getting hiv?

If i'm negative and start taking truvada (emtricitabine and tenofovir) daily, as a preventative medication, what are my chances of getting hiv?

Info from study: In the pivotal study, truvada (emtricitabine and tenofovir) led to an additional 44% HIV protection. No one can answer what your chances of getting HIV with truvada (emtricitabine and tenofovir) since that would also be affected by the type of sexual activity/partners as well. Keep in mind people in this study also received counseling and actually had lower risk behaviors in addition to taking the truvada (emtricitabine and tenofovir). http://www.nejm.org/doi/full/10.1056/nejmoa10112. ...Read more

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My bloodwork come back negative for everything. My partner is positive and i wanted to get on truvada (emtricitabine and tenofovir) as a preventative medication.

My bloodwork come back negative for everything. My partner is positive and i wanted to get on truvada (emtricitabine and tenofovir) as a preventative medication.

PreP: This is a very good and wise decision. But, first, more importantly for your sake and his health's sake, he needs to be on HIV medications that effectively suppress his HIV viral load to undetectable. Once he is undetectable it is very unlikely that he will be contagious. I often recommend this site to find the right doctor for you: http://www.Glma.Org. But, get on prep asap. ...Read more

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I have been taking Truvada (emtricitabine and tenofovir) as a preventative medication. Since then I've noticed my stool smells like metal. Is this a problem ? Could this even be related to those meds ?

I have been taking Truvada (emtricitabine and tenofovir) as a preventative medication. Since then I've noticed my stool smells like metal. Is this a problem ? Could this even be related to those meds ?

Truvada (emtricitabine and tenofovir): Truvada (emtricitabine and tenofovir) has proven useful as a preventative medication for HIV. It is generally well tolerated. I have never heard of stool smelling like metal as a side effect of this medication. It is recommended that you have periodic tests of your liver and kidneys while on Truvada (emtricitabine and tenofovir). Although it is probably nothing to worry about, you should tell your doctor and have those tests performed. Good luck. ...Read more

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Antidepressant medication question i'm currently taking wellbutrin for my major depression. I'm also taking trazadone for sleeping. I want to stop taking trazadone, can't sleep anymore. I used to take quetiapine fumarate for years but after blood test,

Antidepressant medication question i'm currently taking wellbutrin for my major depression.  I'm also taking trazadone for sleeping.  I want to stop taking trazadone, can't sleep anymore.  I used to take quetiapine fumarate for years but after blood test,

Sleep medicine doc: You should consult with a sleep medicine doctor. There are over 80 sleep disorders. I am boarded in psychiatry and sleep medicine, so I do both. Twenty percent of people with depression also have sleep apnea, and vice versa. It sometimes takes a team. Your insomnia diagnostic work-up is incomplete unless you have already seen a sleep specialist. Sweet dreams! ...Read more

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Diag Angina, lost erectile function and sexual excitment no prev probs this area I feel related to drugs nicorandil bisoprolol fumarate simvastin?

Diag Angina, lost erectile function and sexual excitment no prev probs this area I feel related to drugs nicorandil bisoprolol fumarate simvastin?

Bisoprolol : Is likely to be the culprit here. If your ED started around the same time as that med you should go see your doc about switching you to something else. I do not recommend you stop it without seeing your doctor. This medication can have a rebound effect and possibley cause you more angina if you stop it in-appropriately. ...Read more

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NEJM says Niaspan 500 does not work. I was just placed on it for 3 months. Also take Fish Oil. Should I contact dr? On HAART drug Truvada (emtricitabine and tenofovir) Tivicay.Help

NEJM says Niaspan 500 does not work. I was just placed on it for 3 months. Also take Fish Oil. Should I contact dr? On HAART drug Truvada (emtricitabine and tenofovir) Tivicay.Help

Science and Life: There is a lot of debate about Niacin. And the science in the NEJM is just one piece of the story and debate. If I remember well you have high Triglycerides. High Triglycerides are more dangerous than niacin and I would see how you do with it before just stopping it. It has worked in individual patients; it is part of the standard of care in HIV medicine. ...Read more

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What do you suggest if my father takes lamivudine and tenofovir for his liver. do these drugs interact with milk thistle?

What do you suggest if my father takes lamivudine and tenofovir for his liver. do these drugs interact with milk thistle?

No Interaction: These medicines do not interact with Milk Thistle. However, before taking any new medications he should make sure his doctor knows about this so that possible interactions can be checked. ...Read more

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What is the difference between bisoprolol hemifumarate and fumarate?

What is the difference between bisoprolol hemifumarate and fumarate?

TheyArePolymorphs: They have the same chemical formula but slightly different chemical structure.They are virtually the same and used for same indications.Does not matter which polymorphic salt you took ...Read more

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How does tenofovir cause renal failure ?

How does tenofovir cause renal failure
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Accumulation: Tenofovir, or viread, (tenofovir) is a powerful antiviral medication for hiv. It has, in rare cases, been thought to contribute to renal failure. The thought is that the drug and metabolites of the drug accumulate in the tubule of the kidneys, causing damage to the filtering system. However, some studies have shown that tenovir is no more toxic than other antivirals. ...Read more

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Which generic has less side effects? bisoprolol hemifumarate or fumarate

Which generic has less side effects? bisoprolol hemifumarate or fumarate

No difference: As a former chemistry major, I do not see much difference between the two given that the basic chemical is the same. ...Read more

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Why can't I sleep without medicine quetiapine fumarate?

Why can't I sleep without medicine quetiapine fumarate?

Answer: You should talk to your prescribiung doctor. Itcould be as simple as your body is used to the med. But you should not be experimanting with out talking to your doctor. ...Read more

Dr. Julie Abbott
15 doctors shared insights

Viread (Definition)

Viread is a nucleoside reverse transcriptase inhibitor which is a kind of drug used for HIV (anti-viral ...Read more