Doctor insights on:
Low: Temodar (temozolomide) is a chemotherapy drug that is taken orally. It works by damaging dna in cancer cells. It can also damage dna in normal cells, and in humans there is a small risk of developing acute leukemia as a result of temodar (temozolomide) use. This can happen years after taking the drug. The risk is less than a 1 in 100 chance, and the potential benefit is much higher than the benefit for treating cancer! ...Read more
Temodar (temozolomide) is indicated in adults in certain blood cancers. FDA recommendations often reflect what the drug company submitted during research. In Pediatrics, we often use medication OFF LABEL - meaning it's not listed as approved for children. However, many private research helps us determine if pediatric uses are helpful. Discuss your concerns with your specialist.
http://www. Drugs. Com/pro/temodar. Html ...Read more
What is a good treatment for glioblastoma multiforme if traditional radiation and temodar (temozolomide) are not working?
After ressection on a milagnant grade 3 anaplastic astrocytoma is temodar (temozolomide) and radiation the best treatment option? If not what else is available?
Yes: The standard of care is radiation and temador after resection. Since this is an aggressive cancer the alternatives are research trials. But it's been decades and very slow progress has been made. When further recurrence occurs more surgery plus radioactive implants or radiosurgery may be tried but has shown little benefit. ...Read more
LACK OF APPETITE AND EXTREME FATIGUE AFTER RADIATION AND TEMODAR (temozolomide) FOR GBM IS THIS COMMON AND WHAT IS TO BE DONE TO HANDLE IT?
SX's of cancer RX: Yes, unfortunately, these symptoms often plague patients under treatment for various cancers. Appetite stimulants can be given for example progestational agents (e.g. megestrol acetate 160-180 mg BID), corticosteroids (e.g. Decadron (dexamethasone) 4 mg/day or prednisone 10-20 mg/day), and cannabinoids (dronabinol 5-20 mg/day). Nausea should be treated as well as pain. A nutritional consult. Exercise as tolerated ...Read more
I have 4 months left of temodar (temozolomide) for brain tumor treatment I am getting severe headaches where the surgery was is there something I can do to help this?
I am having headaches while going through temodar for brain tumor my doctor told me to take tylenol (acetaminophen) is there something else I could ask my doc to help?
STEP therapy: First, you must rule out brain cancer recurrence then you can take opioid pain meds in a step fashion if acetominophen is not enough. You can start with lortab, percocet, then increase from there. Your oncologist can manage your pain. You should avoid tramadol due to potential of causing seizures. ...Read more
Starting temodar (temozolomide) prescription for treatment of anaplastic astrocytoma brain tumor. What are strange side effects?
Not strange: Temodar, (temozolomide) like other chemotherapy agents, may cause nausea and vomiting, may cause a general sense of "malaise", and will have a risk of lowering your white blood cell counts and making you more susceptible to certain infections. It is generally well-tolerated however, more so than most other agents used for astrocytomas. There are no "strange" side-effects that I know of. Talk to your doctors. ...Read more
There are none...: Even the strongest opiates only "take the edge off" for people in chronic pain. Meds are only one part of dealing with the pain. A useful tool, but pain is so necessary for survival that we are not "allowed" to monkey with it much. In acute pain, the transition from miserable to less miserable can be great. In chronic pain, it's just part of the plan. ...Read more
Sometimes: Sometimes they are. For the most part, expired drugs simply lose potency once past their expiration date. There are, however, some drugs that actually become harmful if taken after they expire. As such, it is best to throw out any medications you have after a year. ...Read more
ASPRIN: Actually no one has decided on 'safest'. Asprin has been around since before you were born and unless you take too much (yes, too much of anything isn't good) most people are okay with it. If the pain it too severe for asprin you need to know what causes it. Good diagnosis is called for. See the dr. ...Read more
Applies to skin: Topical just refers to how a medication is applied. In this case to the skin and is meant to treat local skin problems. Some meds are applied to the skin but are meant to be absorbed into the body in which case we use the term "transdermal" since it is meant to pass through the skin to affect the whole body. ...Read more
Why R you depressed?: If your depression is affecting your life and/or those around you and you have trouble dealing with it or not knowing how to etc. It is very reasonable to seek help, either from a therapist, your physician/nurse, or both. Psychotherapy may be adequate for some, others may need both meds (many choices, depending on your symptoms/needs) and therapy. Consult doc. Good luck. ...Read more
RSD, or: Complex regional pain syndrome can be difficult to treat and each patient needs to be treated differently. Opioid medications are definitely not the first option. Consider medications that affect nerve pain most, like neuromodulators such as gabapentin. Clonidine has been found to help some as well. Stellate ganglion blocks can be diagnostic/therapeutic. Consider topical ketamine creams as well. ...Read more
Antacid: An h2 blocker (like Pepcid (famotidine) or its generic) once or twice daily, provides relief for many after about a week. If this fails, a proton pump inhibitor (ppi--like Prilosec or its generic) will often work where h2's have failed. If both fail after at least one week trial of each, see your dr or a GI dr for eval. ...Read more
Elimiron: Elmiron (pentosan) is a medication that is fda approved for ic (interstitial cystitis). The main way it works is not truly known, but it may help with coating the lining of the bladder. In ic, inflammation may be the main cause of pain. Have you seen a doctor in regards to this? Hopefully, you can get the proper testing and see if this med would work well for you. ...Read more
Some people do: ADD medications, stimulants in particular may change the way you feel. Some feel calmer or less restless or agitated. Some feel more focused. Some feel increased restlessness. But in short, yes, stimulants can make you feel differently than prior to taking them. ...Read more