Top 20 Doctor insights on: Taxol half life
Half lives: For Taxol, the half-life is dependent upon the length of the infusion. If it is a three hour infusion, the half-life is approximately 24 hours, but for a 24 hour infusion, it is about 52 hours. For carboplatin, the retention half life can be as much as 30 hours. Hope that helps. ...Read more
Not too many:
Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil).
Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read more
Taxol (paclitaxel): TAXOL (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to TAXOL (paclitaxel) or other drugs formulated in Cremophor® EL (polyoxyethylated castor oil). TAXOL (paclitaxel) should not be used in patients with solid tumors who have baseline neutrophil counts of ...Read more
Drug from a tree: Taxol is a chemotherapy drug used commonly to treat breast cancer. It's generic name is paclitaxel. It is also used to treat ovarian, lung, prostate, bladder, melanoma, esophageal cancer and other solid tumor cancers. It is made fromthe pacific yew tree bark. It works by preventing the cancer cells from dividing and therefore stops their growth. ...Read moreSee 1 more doctor answer
Discontinued: Taxol (paclitaxel) has been discontinued in the us. There was originally concern because of the environmental impact of its original sourcing, no longer used, from the pacific yew. In addition, the assignment of rights, and even the name itself, to bristol-myers squibb were the subject of public debate and congressional hearings. ...Read moreSee 2 more doctor answers
Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol (paclitaxel) works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read moreSee 1 more doctor answer
Stops cell division: Taxol (paclitaxel) is a chemotherapeutic agent that act to arrest rapidly dividing cells such as cancer cells. As such, it can also impede certain "normal" cell division such as white blood cels. Cell counts must be monitored frequently during treatment with this agent. ...Read moreSee 1 more doctor answer
Taxol (paclitaxel) or Paclitaxel is a chemotheaputic drug which is used to treat a variety of cancers including lung, breast, ovarian and head and neck cancers.
It works by interfering with cell division.
It is produced by a fungus that lives in a south american tree bark. ...Read more
No: Taxol (paclitaxel) is a chemotherapeutic agent used to treat malignant, metastatic disease. Pneumonitis is an inflammatory process that needs antibiotics to bring the disease under control. One of the complications of chemo like Taxol (paclitaxel) is suppressing the immune system. As such reports appear that pneumonitis following the use of Taxol (paclitaxel) as in breast cancer occurs following the use of this agent. ...Read more
Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read moreSee 1 more doctor answer
YES: Should only be used under the direction of an oncologist ...Read more
No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read moreSee 1 more doctor answer