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Doctor insights on: Tapering Off Depakote

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My son is taking 500mg Depakote 2 times a day. We want to taper off this med which causes him to have a lot of constipation and aggression.

My son is taking 500mg Depakote 2 times a day. We want to taper off this med which causes him to have a lot of constipation and aggression.

Discuss w/ physician: Tapering such a medication should be under the guidance of the prescribing physician. Depakote is often prescribed by neurologists and psychiatrists for different conditions. You should discuss the symptoms with the prescribing neurologist or psychiatrist before making any changes because there may be other reasons. Http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a682412.html ...Read more

Dr. Jeffrey Cohen
249 Doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, . Etc. It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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Is Depakote stored in fat?

Is Depakote stored in fat?

No: Depakote is metabolized almost exclusively by the liver via glucuronide conjugation and mitochondrial beta oxidation. It is excreted in the urine. Further information: http://dailymed. Nlm. Nih. Gov/dailymed/lookup. Cfm? Setid=ded64147-7a43-4055-accc-2c011828079d ...Read more

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Please describe the medication: depakote?

Seizure medication: Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, weight gain and tremors. ...Read more

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Is Depakote a mood stabalizer?

Is Depakote a mood stabalizer?

Can be...: Depakote is in the class of anticonvulsants medications however in psychiatry it is also considered a mood stabilizer. Uses include the treatment mania, epilepsy, and migraine prophylaxis, . ...Read more

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Can Depakote cause hallucinations?

Not normally: It has been reported in cases in which encephalopathy occurred. ...Read more

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Does Depakote have any street value?

Does Depakote have any street value?

No: It does not cause a high and has some pretty serious potential side effects if not carefully monitored. It also does not enhance thinking. Depakote has been studied as a treatment for behavioral problems in dementia and autism (among other disorders) but was not found to have benefits for either disorder. Therefore I cannot see how it could be used as a street drug. ...Read more

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Can you take cholest-off with depakote?

Can you take cholest-off with depakote?

Yes, no problem: Cholest-off is an otc prep that really does reduce cholesterol levels by blocking fat absorption, but will not affect Depakote levels or effects on your condition. If you have any doubt, easy to check your Depakote blood level. ...Read more

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What causes Depakote blood to fluctuate?

What causes Depakote blood to fluctuate?

Depends: Depakote levels can vary based on when your last dose was in relation to your blood being drawn for your test. They vary by person. Other medications can affect the metabolism of Depakote and intern cause the levels to fluctuate. Various medical conditions also can affect the levels. ...Read more

Dr. Alan Ali Dr. Ali
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What would a Depakote overdose feel like?

Dr. Alan Ali Dr. Ali
1 doctor agreed:
What would a Depakote overdose feel like?

Depakote: Depending on dose taken, dizziness, upset stomach, tremors, headaches, etc. ...Read more

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What are the tests for Depakote overdose?

What are the tests for Depakote overdose?

Exam & blood test: Sedation plus history suggestive of overdose are usual first signs, confirmed by blood test. Any significant concerns of overdose should be considered an emergency with immediate contact with your doctor or trip to an emergency room. ...Read more

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Side effects of depakote, do they go away?

Side effects of depakote, do they go away?

Sometimes: Some side effects go away, or at least get better, over time, and some do not. It sounds like you really need to discuss the situation in more detail with the person prescribing the depakote. ...Read more

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Does Depakote slow down your metaboliam a lot?

Does Depakote slow down your metaboliam a lot?

No: Depakote frequently causes sleepiness and appetite increase. The combination of the two often results in weight gain and a feeling of having little energy. This is the medication, not a change in metabolism. ...Read more

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Why would Depakote be prescribed for a patient?

Why would Depakote be prescribed for a patient?

Mood, pain, seizure: Depakte is an anticonvulsant medication so can be used for seizures. However many newer drugs seem better for seizures with fewer side effects. Now departed is mainly used as a mood stabilizer for people with bipolar disorder, or or several types of chronic pain syndromes. ...Read more

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What effects does Depakote have on the human body?

Depakote: Some of the more serious effects include a severe skin reaction, weakness, easy bruising, lethargy, and confusion. Others include hair loss, vision changes, changes in menstruation, and GI upset. ...Read more

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Can I tak depakote 250 and fioricet 300-50-40 together?

Can I tak depakote 250 and fioricet 300-50-40 together?

There is interaction: According to FDA there is drug interaction and it depends on how long you are going to take them together. Discuss with your Doctor or pharmacist before you take them together ...Read more

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What is the definition or description of: Depakote overdose?

What is the definition or description of: Depakote overdose?

OD=toxic blood level: Manifestations of depakote OD are: Hyperthermia/hypothermia, Tachycardia,
Hypotension (with severe overdose), Cardiac arrest (with severe overdose), Respiratory depression necessitating intubation. Typical dosing of depakote are 500mg 2-3 times per day for seizures and bipolar disorder. However, the blood level is what really matters. The therapeutic l range= 50-125ug/ml; toxic range=>150ug/ml. ...Read more

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Do some of the effects of Depakote on fetus wear off over time?

Avoid in pregnancy!: Depakote should be the last drug to be considered for epilepsy therapy in pregnancy because of its strong embryotoxicity and causal relationship with severe fetal anomalies (ranging from anencephaly and myelomeningocele to valproic acid embryopathy). ...Read more

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What is the definition or description of: side effects of depakote?

Mostly mild: Dyspepsia and/or weight gain are common. A rare side effect is a liver and blood allergy/dysfunction. Less common are fatigue, peripheral edema, acne, dizziness, drowsiness, hair loss, headaches, nausea, sedation, and tremors. An increase of ammonia levels in the blood, which can lead to vomiting and sluggishness. ...Read more

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Can Depakote help to alleviate hallucination symptoms or cause them?

Can certainly cause: Depakote, terms of psychiatric effects is mostly used when trying to stabilize a person's mood and treat things such as Rage/Anger of an excessive nature or when someone becomes manic or undirectable. I don't that it is used to any extent in the treatment of hallucinations. For neurologists DEPAKOTE is most useful as an antiseizure as well as headache treatment medication. ...Read more

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I missed two doses of Depakote but took my morning dose. Am I ok to drive?

Your decision: If you have worked with your doctor to establish a stable dosing that does not give you concerning side effects you should be ok if you miss doses. Make sure that you don't take extra doses to make up for the ones you missed. ...Read more

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If off of Depakote for several weeks, how long does it take to correct the QT syndrome?

QT prologation: With Depakote occurred with only 27 of 27 thousand people who had side effects in 2014 while taking Depakote according to one source. Of those who had it most were taking other medications as well. There is no data on how long it takes to recover. You might take this up with the prescribing doctor or a cardiac electrophysiologist. Short QT syndrome also occurs but just as rarely ...Read more

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Off Depakote for 6 days. No migraines. Should I assume they will return and resume meds?

Unsure: Just because you have not had a migraine in 6 days being off depakote, doesn't mean your migraines won't return. At the same time, your migraines might have, "calmed down." if they return, then you can resume the depakote. But, if you stopped the Depakote due to side affects, there are other meds to try. ...Read more

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Can you suddenly stop taking Depakote after two weeks at 750mg? Medication was prescribed as a mood stabilizer.

No: Everyone's body chemistry and drug tolerance/sensitivity is different. Whenever possible is best to titrate off psych meds, meaning take one every other day for a week and then one every three days the following in your case. Additionally always let your physician know what you're doing so s/he can better assist you when you go back for your next apt. ...Read more

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If you take Depakote and feel normal and at peace for the first time ever. Does it prove you have a mood disorder?

No: No. You would have to have the symptoms of mood disorders. Even people without the criteria of mood disorder feel better on Depakote for some reason. I have a few epilepsy and migraine patients who feel better on it. ...Read more

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It has been 6 days since I have taken depakote. How long before migraines may return, or do I assume they will and resume the medicine?

They are not gone: Depakote does not cure migraine! it can break a cycle of repetitive migraine, but the tendency will remain. Learn good management. Consider Depakote again only if they become frequent and disruptive. Migraine tendency is life long - learn to live with the risk. ...Read more

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Depakote, which I took (1, 000 mg/day) for 20 years, caused very high shbg levels. Recently discontinued it. How long before shbg back to normal?

Is damage from depak: Depakote usually causes liver problems early in trealment and not 20 years after starting the drug.
Your leukemia and the sprycel (dasatinib) may be the cause of the enzyme elevation. Sprycel (dasatinib) in involved in cyp450 in the liver and may be throwing your liver into trouble., more likely that the depakote. ...Read more

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Is Depakote good for ocd?

Depakote: Usually Depakote helps for mood and anger, impulsiveness. ...Read more

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Can you please discuss Depakote used for?

Sz and HA's: Depakote is approved for both migraine headaches, and epilepsy. It is considered a broad spectrum anti-epileptic drug. It can prevent both migraine headaches, and a variety of seizures if taken on a regular basis. ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more