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Doctor insights on: Tamoxifen Therapy For Breast Cancer

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When is tamoxifen for breast cancer treatment?

When is tamoxifen for breast cancer treatment?

Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read more

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Dr. Barry Rosen
4,417 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Hormone therapy for prostate cancer?

Hormone therapy for prostate cancer?

Treatment: Hormone therapy consists of medications that decrease the effects of testosterone on prostate cancer and a man's body. Prostate cancer growth is primarily fueled by testosterone. If testosterone is absent/ineffective, prostate cancer hopefully would stop growing. Hormone therapy has several varieties including pills and injections. Given for advanced disease or at times prior to radiation. ...Read more

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Is combined tamoxifen plus hormonal therapy better for breast cancer?

Is combined tamoxifen plus hormonal therapy better for breast cancer?

No: Studies show that adding tamoxifen to an aromatase inhibitor (what i assume you mean by "hormonal therapy") was not better than either drug alone. ...Read more

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Who takes arimidex (anastrozole) for breast cancer?

Who takes arimidex (anastrozole) for breast cancer?

Post menopausal ER+: Women who are post-menopausal and have estrogen receptor positive breast cancer. ...Read more

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Is radiation effective for breast cancer?

Is radiation effective for breast cancer?

Very effective.: Radiation therapy (rt) is never a primary treatment for breast cancer, but rather a supplement to surgery for the local treatment of breast cancer. Rt is mandatory following breast conserving surgery: local recurrence rates are decreased from >25% to <5% with rt. Rt is also used after mastectomy for patients that are at high risk for local recurrence. ...Read more

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After effects of radiation therapy for breast cancer?

After effects of radiation therapy for breast cancer?

Side effects include: Acute effects include erythema hyperpigmentation of skin, moist desquamation of skin long term effects of radiation therapy for breast cancer include: radiation fibrosis of lung lymphedema of the affected side upper extremity myocardial injury hypothyroidism brachial plexus injury risk of second neoplasm (radiation induced malignancy). ...Read more

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How effective is radiation therapy for breast cancer?

How effective is radiation therapy for breast cancer?

Very effective.: Radiation therapy (rt) is never a primary treatment for breast cancer, but rather a supplement to surgery for the local treatment of breast cancer. Rt is mandatory following breast conserving surgery: local recurrence rates are decreased from >25% to <5% with rt. Rt is also used after mastectomy for patients that are at high risk for local recurrence. ...Read more

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Is zoladex (goserelin) effective for breast cancer?

Is zoladex (goserelin) effective for breast cancer?

Depends: Your physician may offer this as one of a variety of possible hormonal manipulations if and only if the pathology team says the tumor is hormone-sensitive. When it works, it is often strikingly successful. ...Read more

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Can radiation therapy for breast cancer give me leukemia?

Can radiation therapy for breast cancer give me leukemia?

Not likely: Leukemia is more likely as a cancer caused by chemotherapy since it exposes more bone marrow. Radiation to the breast will expose very little bone marrow and leukemia is not likely but nothing is impossible. ...Read more

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Does chemotherapy work for breast cancer?

Does chemotherapy work for breast cancer?

It depends: Chemo treats the whole body to kill cancer cells that may have escaped from the breast tumor. Sometimes chemo is used to shrink the breast tumor before surgery (neoadjuvant chemotherapy). Breast cancers that respond best to chemotherapy are those with a high ki-67 (proliferation rate), er negative, and/or her2 positive. ...Read more

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Hormonal effects of chemotherapy for breast cancer?

Hormonal effects of chemotherapy for breast cancer?

Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more

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Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Small risk: Tamoxifen is asociated with a small (less than 5%) risk of uterine cancers, women on tamoxifen require regular gynecologic checkups every 6-12 months and high-risk women may need ultrasound screeenings too. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?

Estrogen supression: In general, aromatase inhibitor is only indicated for postmenopausal women ;not for premenopausal; while on the other hand, tamoxifen can be given either in pre or postmenopausal. Only thing is that tamoxifen can cause a little bit higher risk for complication -i.e. Risk for blood clots and risk for develping uterine cancer- when used in older population- age of -65 Y.O. Or above. ...Read more

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Does pr-negative breast cancer respond to tamoxifen?

Does pr-negative breast cancer respond to tamoxifen?

It depends.: Tamoxifen is used to treat hormone-sensitive breast cancer. This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective. ...Read more

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How effective is radiation therapy for treating breast cancer?

How effective is radiation therapy for treating breast cancer?

Fairly effective: Radiation plays an important role in treating breast cancer. In the neoadjuvant setting it can reduce the size of a relatively large lesion making surgery more effective. It can be used to treat micro disease in axilla and after lumpectomy can be used to enhance survival and reduce local recurrence. In metastatic bone disease it can control in not eliminate disease. ...Read more

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Hormone therapy for menopausal symptoms cause breast cancer?

Hormone therapy for menopausal symptoms cause breast cancer?

NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more

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Is Xeloda (capecitabine) effective for breast cancer?

Is Xeloda (capecitabine) effective for breast cancer?

Xeloda (capecitabine) for breast ca: Xeloda (capecitabine) also known as Capecitabine is a very effective oral chemotherapy drug used for metastatic or stage 4 breast cancer. It can be used by itself (mono therapy) or as part of combination chemotherapy. Major side effects include diarrhea, hand foot syndrome, nausea and small chance of coronary spasm. It is well tolerated. Patients on Xeloda (capecitabine) need to be followed closely by medical oncologists. ...Read more

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Does tamoxifen for breast cancer put me at risk for uterine cancer?

Does tamoxifen for breast cancer put me at risk for uterine cancer?

Yes. like ERT: The increase risk is similar to that of unopposed estrogen replacement therapy. It is important that all your doctors (esp your gyn in this case) are aware what medications you're taking and report any irregular vaginal bleeding/discharge or other pelvic symptoms. ...Read more

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Dr. Sean Canale
639 doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


Dr. Mark Hoepfner
1,069 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more