Doctor insights on:
This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more
Will the medication tamoxifen effect the results of a MRI of the brain? Would this medication cause the brain MRI to be inaccurate?
Depends: You need to get specific info from your doctors, not generalized info from the internet. ...Read more
Will tamoxifen/nolvadex effect the results of an MRI of the brain? I am taking this medication and just had a brain MRI done.
My dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this healthy?
Benefit/risk: Tamoxifen is a SEAM (selective estrogen receptor modulator). It inhibits estrogen receptor pathway in breast, but stimulates it in ovary and uterus. It may increase fertility for a time, but reduce later due to constant stimulating. Its stimulating effect can also increase risk of uterine cancer. Other side effects from tamoxifen include thrombosis, stroke, etc, esp at long-term use. ...Read more
What do you suggest if my dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this ok?
Yes: Tamoxifen is used to prevent breast cancer where it suppresses estrogen binding, it can act as an estrogenic stimulus on ovarian tissue initiating ovulation induction by a mechanism similar to clomiphene citrate. This drug Clomid is able to bind to estrogen receptors in the hypothalamus. Preventing the brain from seeing the negative signal from estrogen This stimulates production of FSH. ...Read more
Immediately a breast cancer survivor. On the drug tamoxifen, I missed a day. Can I take 2 pills in one day?
No...: No, if you missed it completely do not double up. In the future if you miss a dose and remember within 8 hours you can take the dose. A weekly pill case can be a great reminder for taking pills, there are also dose reminder apps available. ...Read more
Blocks estrogen: Some breast cancer cells have receptors on them that bind to estrogen in order to grow. Tamoxifen acts as an "antagonist" and blocks estrogen from binding to these receptors on the cancer cells by binding to them first. With tamoxifen sitting in estrogen's place, the cancer cell can no longer grow. ...Read more
Once per day:
Tamoxifen is most commonly used to treat breast cancer. The dose is (usually) 20mg per day and taken for 5 years. This medication is also used for people considered "high risk" for breast cancer to help decrease their risk of developing it in the future.
I recommend you speak with your oncologist about specific recommendations for your case. ...Read more
Blocks ER: Tam binds and blocks signals to the estrogen receptor present in er+ breast cancer. While this has benefits in cancer treatment it produces side effects - menopausal symptoms, possible uterine wall thickening & even malignancy if ignored, & increased risk of blood clots (similar to hormone replacement). In most cases of ca the benefits far outway the risks but must be weighed in risk reduction. ...Read more
Yes.: Women with a history of ductal-carcinoma-in-situ (dcis) may have a 50% reduction in developing a second breast cancer when taking tamoxifen for 5 years ("chemoprevention"). Furthermore, following a lumpectomy, the combination of tamoxifen and radiation therapy may have a decreased risk of cancer recurrence in the affected breast greater than either therapy alone. ...Read more
This medication is used to:
treat breast cancer that has spread to other parts of the body in men and women.
Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.
Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer that does not spread. ...Read more
Nothing: Simply resume your regular dosing and tell your doctor who prescribed it. ...Read more
Side effects?: The most experienced side effects of all hormonal therapy are menopausal symptoms (ie.Hot flashes, etc). There is a small increased risk of blood clots similar to hormone replacement therapy, in women with an intact uterus, there can be irreg bleeding and thickening of the uterine wall. If ignored this can rarely progress to uterine cancer that can be cured with a hysterectomy. ...Read more
Anti-estrogen: Tamoxifen is a molecule that can attach to estrogen receptors (sticky hands on cells that like estrogen). If estrogen (female hormone) binds these receptors it typically causes growth/ turn cell on. Tamoxifen mimics estrogen but can have the opposite effect, hence anti-esteogen. Tamoxifen by attachment can turn cells off (in some breast cells) or turn cell on (in uterus). ...Read more
It Depends: It depends on what the tamoxifen is being used to treat. If used to treat breast cancer, it is mostly prescribed by an oncologist. However, tamoxifen can also be used as treatment for severe breast pain/fibrocystic disease, or for breast cancer prevention. In those cases a primary care physician, general surgeon, or gynecologist may prescribe it. ...Read more
Yes: Tamoxifen is most commonly prescribed for the treatment of hormone (+) breast cancer. While tamoxifen may cause birth defects during pregnancy, it actually can increase ovulation, thus increasing fertility. Accordingly, premenopausal women taking tamoxifen for breast cancer treatment must use (nonhormonal forms of) birth control. ...Read more
The common ones are bone pain; constipation; coughing; hot flashes; muscle pain; nausea; tiredness; vaginal discharge; weight loss.
Severe ones are even a more comprehensive list - allergic reactions, vaginal bleeding, chest pain, coughing up blood, dark urine, decreased libido and so. ... On. ...Read more
Speak to your doctor:
This is not the usual regimen for tamoxifen. It is usually recommended for daily use and intake for the best effect. Was this recommended by your doctor? If so, you need to find out why this deviates from the standard recommendation.
If you are making up your own regimen, please do not proceed until you speak with your physician. ...Read more