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Doctor insights on: Tamoxifen Medication

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Please describe the medication: tamoxifen?

Please describe the medication: tamoxifen?

Tamoxifen: Treats advanced breast cancer in men and women, and early breast cancer in women. Also may prevent breast cancer in women who are at a high risk because of age, family history, or other factors. ...Read more

Dr. Sean Canale
638 Doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


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Will the medication tamoxifen effect the results of a MRI of the brain? Would this medication cause the brain MRI to be inaccurate?

Will the medication tamoxifen effect the results of a MRI of the brain? Would this medication cause the brain MRI to be inaccurate?

Tamoxifen MRI: Tamoxifen can sometimes cause neurological side effects such as mood changes. However, there is no data that suggests that tamoxifen changes the anatomy or imaging of the brain. Tamoxifen is a very effective anti-estrogen drug for breast cancer prevention and treatment. ...Read more

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What are possible reactions to drug tamoxifen?

What are possible reactions to drug tamoxifen?

3 main ones: 1-blood clots/ strokes
2-endometrial carcinoma
3-cataracts
hot flashes/ dryness. ...Read more

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My dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this healthy?

Benefit/risk: Tamoxifen is a SEAM (selective estrogen receptor modulator). It inhibits estrogen receptor pathway in breast, but stimulates it in ovary and uterus. It may increase fertility for a time, but reduce later due to constant stimulating. Its stimulating effect can also increase risk of uterine cancer. Other side effects from tamoxifen include thrombosis, stroke, etc, esp at long-term use. ...Read more

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What do you suggest if my dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this ok?

What do you suggest if my dr. Wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this ok?

Yes: Tamoxifen is used to prevent breast cancer where it suppresses estrogen binding, it can act as an estrogenic stimulus on ovarian tissue initiating ovulation induction by a mechanism similar to clomiphene citrate. This drug Clomid is able to bind to estrogen receptors in the hypothalamus. Preventing the brain from seeing the negative signal from estrogen This stimulates production of FSH. ...Read more

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Immediately a breast cancer survivor. On the drug tamoxifen, I missed a day. Can I take 2 pills in one day?

Immediately a breast cancer survivor. On the drug tamoxifen, I missed a day. Can I take 2 pills in one day?

No...: No, if you missed it completely do not double up. In the future if you miss a dose and remember within 8 hours you can take the dose. A weekly pill case can be a great reminder for taking pills, there are also dose reminder apps available. ...Read more

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Could I use Prozac (fluoxetine) together with the breast cancer drug tamoxifen?

Could I use Prozac (fluoxetine) together with the breast cancer drug tamoxifen?

Maybe: There may be an interaction between tamoxifen and prozac (fluoxetine). There are other effective medications for depression that should be considered. ...Read more

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How does tamoxifen actually work?

How does tamoxifen actually work?

Blocks estrogen: Some breast cancer cells have receptors on them that bind to estrogen in order to grow. Tamoxifen acts as an "antagonist" and blocks estrogen from binding to these receptors on the cancer cells by binding to them first. With tamoxifen sitting in estrogen's place, the cancer cell can no longer grow. ...Read more

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How much tamoxifen is recommended?

How much tamoxifen is recommended?

Once per day: Tamoxifen is most commonly used to treat breast cancer. The dose is (usually) 20mg per day and taken for 5 years. This medication is also used for people considered "high risk" for breast cancer to help decrease their risk of developing it in the future.
I recommend you speak with your oncologist about specific recommendations for your case. ...Read more

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Who should avoid taking tamoxifen?

Blood clots: Pts with a history of blood clots and/or a history of abnormal pap smears should not take tamoxifen. If there is a family history of clotting disorders or uterine cancer, tamoxifen should not be used. ...Read more

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What are the effects of tamoxifen?

Blocks ER: Tam binds and blocks signals to the estrogen receptor present in er+ breast cancer. While this has benefits in cancer treatment it produces side effects - menopausal symptoms, possible uterine wall thickening & even malignancy if ignored, & increased risk of blood clots (similar to hormone replacement). In most cases of ca the benefits far outway the risks but must be weighed in risk reduction. ...Read more

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Is there an alernative to tamoxifen?

Yes: For breast cancer treatment, aroma taste inhibitors are often used in place of tamoxifen, only in post menopausal women. ...Read more

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Which side affects does tamoxifen have?

Minimal: Hot flashes most common. Risk of blood clots (like birth control pills). Also, risk of uterine cancer is higher, but still very low. This risk is only seen in post menopausal women. ...Read more

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What are the common benefits of tamoxifen?

What are the common benefits of tamoxifen?

Kill cancer cells: Tamoxifen is a very effective chemotherapeutic agent to treat breast cancers that have the estrogen receptor. Tamoxifen may also be prescribed to prevent breast cancer in high-risk women: a 5-yr regimen may reduce the lifetime risk of breast cancer by 50%. ...Read more

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Does taking tamoxifen benefit women with cdis?

Does taking tamoxifen benefit women with cdis?

Yes.: Women with a history of ductal-carcinoma-in-situ (dcis) may have a 50% reduction in developing a second breast cancer when taking tamoxifen for 5 years ("chemoprevention"). Furthermore, following a lumpectomy, the combination of tamoxifen and radiation therapy may have a decreased risk of cancer recurrence in the affected breast greater than either therapy alone. ...Read more

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What is the definition or description of: tamoxifen?

Google it: This medication is used to:

treat breast cancer that has spread to other parts of the body in men and women.

Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.

Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer that does not spread. ...Read more

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Is it possible for me to just stop taking tamoxifen?

Of course: But is it advised by yoiur doctor or not? Please check if it is time to stop or not. If you have received the maximum possible benefit, then you can stop it and you will not have ill effects due to tamoxifen. ...Read more

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What happens if you stop taking tamoxifen for a week?

Nothing: Simply resume your regular dosing and tell your doctor who prescribed it. ...Read more

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What are the common risk factors for taking tamoxifen?

What are the common risk factors for taking tamoxifen?

Side effects?: The most experienced side effects of all hormonal therapy are menopausal symptoms (ie.Hot flashes, etc). There is a small increased risk of blood clots similar to hormone replacement therapy, in women with an intact uterus, there can be irreg bleeding and thickening of the uterine wall. If ignored this can rarely progress to uterine cancer that can be cured with a hysterectomy. ...Read more

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What exactly is tamoxifen therapy?

Anti-estrogen: Tamoxifen is a molecule that can attach to estrogen receptors (sticky hands on cells that like estrogen). If estrogen (female hormone) binds these receptors it typically causes growth/ turn cell on. Tamoxifen mimics estrogen but can have the opposite effect, hence anti-esteogen. Tamoxifen by attachment can turn cells off (in some breast cells) or turn cell on (in uterus). ...Read more

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Which kind of doctor administers or prescribes tamoxifen?

Which kind of doctor administers or prescribes tamoxifen?

It Depends: It depends on what the tamoxifen is being used to treat. If used to treat breast cancer, it is mostly prescribed by an oncologist. However, tamoxifen can also be used as treatment for severe breast pain/fibrocystic disease, or for breast cancer prevention. In those cases a primary care physician, general surgeon, or gynecologist may prescribe it. ...Read more

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Does tamoxifen affect fertility?

Yes: Tamoxifen is most commonly prescribed for the treatment of hormone (+) breast cancer. While tamoxifen may cause birth defects during pregnancy, it actually can increase ovulation, thus increasing fertility. Accordingly, premenopausal women taking tamoxifen for breast cancer treatment must use (nonhormonal forms of) birth control. ...Read more

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Is letrozole different from tamoxifen?

Yes: Same general effect - decreases effects of estrogen and improves outcome in er + breast cancer. Mechanism of action (how it works) is different. Letrozole cannot be used in premenopausal women. ...Read more

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What are the side effects of tamoxifen?

Tons: The common ones are bone pain; constipation; coughing; hot flashes; muscle pain; nausea; tiredness; vaginal discharge; weight loss.
Severe ones are even a more comprehensive list - allergic reactions, vaginal bleeding, chest pain, coughing up blood, dark urine, decreased libido and so. ... On. ...Read more

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Is it safe to take tamoxifen every other day?

Is it safe to take tamoxifen every other day?

Speak to your doctor: This is not the usual regimen for tamoxifen. It is usually recommended for daily use and intake for the best effect. Was this recommended by your doctor? If so, you need to find out why this deviates from the standard recommendation.
If you are making up your own regimen, please do not proceed until you speak with your physician. ...Read more

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What are the common side effects of tamoxifen?

Menopausal symptoms: The most common side effects of tamoxifen include hot flashes, changes in menstrual period, vaginal dryness, headaches, fatigue, and GI upset. Less common but more serious side effects include blood clots, strokes, uterine cancer, and cataracts. ...Read more