Top
10
Doctor insights on: Tamoxifen Hormonal Therapy Breast Cancer

Share
1

1
Is combined tamoxifen plus hormonal therapy better for breast cancer?

Is combined tamoxifen plus hormonal therapy better for breast cancer?

No: Studies show that adding tamoxifen to an aromatase inhibitor (what i assume you mean by "hormonal therapy") was not better than either drug alone. ...Read more

See 1 more doctor answer
Dr. Barry Rosen
1,337 doctors shared insights

Breast Cancer (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


2

2
Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?

Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?

Estrogen supression: In general, aromatase inhibitor is only indicated for postmenopausal women ;not for premenopausal; while on the other hand, tamoxifen can be given either in pre or postmenopausal. Only thing is that tamoxifen can cause a little bit higher risk for complication -i.e. Risk for blood clots and risk for develping uterine cancer- when used in older population- age of -65 Y.O. Or above. ...Read more

See 2 more doctor answers
3

3
What is the role of tamoxifen in the treatment of breast cancer?

What is the role of tamoxifen in the treatment of breast cancer?

Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read more

See 1 more doctor answer
4

4
When is tamoxifen for breast cancer treatment?

When is tamoxifen for breast cancer treatment?

Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read more

See 1 more doctor answer
5

5
What are the risks of breast cancer returning within a year of original treatment if taking tamoxifen?

What are the risks of breast cancer returning within a year of original treatment if taking tamoxifen?

Low: Most women do well if their tumor is removed and it is in early stages...With high cure rates of 80-85% for stages 1 and 2.. The chances of return within one year of orginal diagnosis have to be very low, perhaps about 5% in my view. ...Read more

See 1 more doctor answer
6

6
Is tamoxifen a must for er/pr negative menstruating woman for breast cancer treatment?

Is tamoxifen a must for er/pr negative menstruating woman for breast cancer treatment?

No: This and similar medicines are anti Estrogens that block the receptors. So if the patient has negative receptors there is little benefit from the medication. So it's not a must. ...Read more

See 1 more doctor answer
7

7
Is it okay for an oncologist to do breast cancer treatment without tamoxifen?

Is it okay for an oncologist to do breast cancer treatment without tamoxifen?

Yes!: Tamoxifen is only useful in breast cancers which are estrogen receptor positive(er+). So tamoxifen is of no use if the tumor is er negative. Check your tumor's hormone receptor status and you will have the answer to your question>. ...Read more

See 1 more doctor answer
8

8
Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Does taking tamoxifen for breast cancer treatment induce cancer of the womb?

Small risk: Tamoxifen is asociated with a small (less than 5%) risk of uterine cancers, women on tamoxifen require regular gynecologic checkups every 6-12 months and high-risk women may need ultrasound screeenings too. ...Read more

See 1 more doctor answer
10

10
Is tamoxifen safe and can I take it? I am a 67-year-old white female living alone. Last year i had early catch stage-1 breast cancer. I next had a lumpectomy and only one treatment of chemotherapy. I was scheduled for four treatments. The side affects

Is tamoxifen safe and can I take it? I am a 67-year-old white female living alone.  Last year i had early catch stage-1 breast cancer.  I next had a lumpectomy and only one treatment of chemotherapy.  I was scheduled for four treatments.  The side affects

If : If your breast cancer was estrogen receptor-negative then you will not benefit from hormonal adjuvant therapy like tamoxifen (actually women who are past their menopause should be on Arimidex (anastrozole) not tamoxifen) either way you will not benefit from those since your mass is estrogen receptor negative. At 67 you should probably still get radiation as you still have a long life ahead of you...Especially with stage 1 cancer. You have to discuss these options with a breast surgeon... ...Read more

See 2 more doctor answers
Dr. Barry Rosen
4,223 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Sean Canale
638 doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more