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Doctor insights on: Tamoxifen Hormonal Therapy Breast Cancer

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Hormonal effects of chemotherapy for breast cancer?

Hormonal effects of chemotherapy for breast cancer?

Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more

Dr. Barry Rosen
4,357 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Does postmenopausal hormone therapy lead to breast cancer?

Does postmenopausal hormone therapy lead to breast cancer?

Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, i feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read more

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Hormone therapy for menopausal symptoms cause breast cancer?

Hormone therapy for menopausal symptoms cause breast cancer?

NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more

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Is combined tamoxifen plus hormonal therapy better for breast cancer?

Is combined tamoxifen plus hormonal therapy better for breast cancer?

No: Studies show that adding tamoxifen to an aromatase inhibitor (what i assume you mean by "hormonal therapy") was not better than either drug alone. ...Read more

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Hormone therapy for prostate cancer?

Hormone therapy for prostate cancer?

Treatment: Hormone therapy consists of medications that decrease the effects of testosterone on prostate cancer and a man's body. Prostate cancer growth is primarily fueled by testosterone. If testosterone is absent/ineffective, prostate cancer hopefully would stop growing. Hormone therapy has several varieties including pills and injections. Given for advanced disease or at times prior to radiation. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Does radiation therapy cause depression among breast cancer survivors?

Does radiation therapy cause depression among breast cancer survivors?

No: Radiation does not cause this. But the whole process of having cancer and coping with it can lead to depression. Depression should be taken seriously and treated no matter what causes it. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?

Estrogen supression: In general, aromatase inhibitor is only indicated for postmenopausal women ;not for premenopausal; while on the other hand, tamoxifen can be given either in pre or postmenopausal. Only thing is that tamoxifen can cause a little bit higher risk for complication -i.e. Risk for blood clots and risk for develping uterine cancer- when used in older population- age of -65 Y.O. Or above. ...Read more

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Does pr-negative breast cancer respond to tamoxifen?

It depends.: Tamoxifen is used to treat hormone-sensitive breast cancer. This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective. ...Read more

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When is tamoxifen for breast cancer treatment?

When is tamoxifen for breast cancer treatment?

Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read more

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Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Increases risk: Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. ...Read more

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Evista (raloxifene) estrogen receptor for uterine cancer?

Evista (raloxifene) estrogen receptor for uterine cancer?

Unclear Question?: These are somewhat unrelated questions which makes it difficult for me to address your question. Evista (raloxifene) is not used for treating cancer...It is sued for treatment/prevention of osteoporosis. Estrogen receptors are specialised protein receptors found in breast cancer.Uterine cancer has little bearing on either of the two references you have listed. ...Read more

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Can breast cancer recur after radiation therapy?

Can breast cancer recur after radiation therapy?

Yes: No matter what treatment, cancer of the breast does not have 100 % results. So with lumpectomy and radiation cancer can still recurr. This is why patients need to follow with all their doctors for exams and x-rays. If there is a recurrence other options exist such as mastectomy. ...Read more

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Is zoladex (goserelin) effective for breast cancer?

Is zoladex (goserelin) effective for breast cancer?

Depends: Your physician may offer this as one of a variety of possible hormonal manipulations if and only if the pathology team says the tumor is hormone-sensitive. When it works, it is often strikingly successful. ...Read more

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Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?

Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?

Often: There is increasing data based on the oncotype DX test in women with 1-3 positive notes that shows that some women will not get much benefit from chemo and some will get a great deal. It can be useful in cases where a woman is reluctant to take chemo. This is done on tissue that has been already removed. Most oncologists believe that women who have multiple positive nodes should get chemotherapy. ...Read more

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Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read more

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Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Unknown: Breast enhancement pills are not regulated and therefore may have various unknown substances in them. Some of those substances, especially if they include estrogen, may increase risk of cancers. ...Read more

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Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Not exponentially: Data from the whi (women's health initiative) study show that estrogen alone does not significantly increase the risk of breast cancer, especially if started within 5 years of menopause. However, estrogen + Progesterone (needed when women still have a uterus to prevent uterine cancer) increases the risk of breast cancer to about 2x the baseline risk. Progesterone appears to be the "bad guy". ...Read more

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Dr. Sean Canale
638 doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


Dr. Mark Hoepfner
1,064 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more