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Doctor insights on: Tamoxifen Breast Hormone Receptors

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Evista (raloxifene) estrogen receptor for uterine cancer?

Evista (raloxifene) estrogen receptor for uterine cancer?

Unclear Question?: These are somewhat unrelated questions which makes it difficult for me to address your question. Evista (raloxifene) is not used for treating cancer...It is sued for treatment/prevention of osteoporosis. Estrogen receptors are specialised protein receptors found in breast cancer.Uterine cancer has little bearing on either of the two references you have listed. ...Read more

Dr. Sean Canale
638 doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


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Are brca hormone receptors?

Are brca hormone receptors?

No: Brca genes are important in repairing damaged dna. Mutations in these genes allow defective dna to replicate and turn the cells with defective dna into turmors. ...Read more

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Chemotherapy hormone receptor positive node breast cancer?

Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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What is estrogen receptor positive breast cancer?

What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Tamoxifen is given to breast cancer patients to suppress estrogen or both estrogen & progesterone?

Estrogen: Tamoxifen is given to individuals with specific breast cancers that are driven to grow by the presence of estrogen receptors. Tamoxifen interferes with the activity of estrogen in the breast, preventing cancer growth. The role of Progesterone receptors is unclear, though Progesterone receptors in breast cancer are generally associated with estrogen receptors, making tamoxifen an effective therapy. ...Read more

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Does postmenopausal hormone therapy lead to breast cancer?

Does postmenopausal hormone therapy lead to breast cancer?

Very low Risk: With due respect. The landmark study, whi, is called into question in so many ways. The nih spent millions to answer very little. As an re, i feel there are many facets to HRT and a careful and comprehensive evaluation of the literature supports a very minimal at best increase in breast cancer and the evidence points to the progestin component only (provera). Consultation warranted. ...Read more

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Hormone therapy for menopausal symptoms cause breast cancer?

Hormone therapy for menopausal symptoms cause breast cancer?

NO BUT INCREASE RISK: Hormone therapy does not cause breast cancer but it does increase your risk of breast cancer. According to the national nurses health study using hormone replacement therapy for 10-15 yrs increases risk about 20%, if used more than 15 yrs it doubles to around 40%. Talk to your doctor to help you decide how to better manage postmenopausal symptoms. ...Read more

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Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?

Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?

Often: There is increasing data based on the oncotype DX test in women with 1-3 positive notes that shows that some women will not get much benefit from chemo and some will get a great deal. It can be useful in cases where a woman is reluctant to take chemo. This is done on tissue that has been already removed. Most oncologists believe that women who have multiple positive nodes should get chemotherapy. ...Read more

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Could premerin homone replacement cause Paget breast cancer?

Could premerin homone replacement cause Paget breast cancer?

Unlikely: We think that combined hormone replacement including estrogen and Progesterone cause an increase in breast cancer of which paget's disease if the breast is a type. Premarin (conjugated estrogens) only contains estrogen. ...Read more

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Does nolvadex (tamoxifen) decrease testosterone production in males?

Does nolvadex (tamoxifen) decrease testosterone production in males?

No: Nolvadex, a brand of tamoxifen, is a selective estrogen receptor modulator. As such, there are some small studies that suggest that it can actually increase testosterone production in med. Similarly, so can aromatase inhibitors which decrease conversion of t into e. Check out http://en.Wikipedia.Org/wiki/list_of_drugs_banned_from_the_olympics for a list of banned substances in competition & why. ...Read more

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Does progesterone or conjugated estrogen enhance breasts?

Does progesterone or conjugated estrogen enhance breasts?

Maybe: Estrogens can quite possibly, but individual results would vary widely. That also isn't a usual medical reason for using those drugs. ...Read more

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Who takes arimidex (anastrozole) for breast cancer?

Who takes arimidex (anastrozole) for breast cancer?

Post menopausal ER+: Women who are post-menopausal and have estrogen receptor positive breast cancer. ...Read more

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Can tamoxifen or raloxifene reduce male breasts (gynemostia)?

Can tamoxifen or raloxifene reduce male breasts (gynemostia)?

No.: Male breast enlargement at age 79 is usually due to weight gain and decreasing testosterone, not excess estrogens. Anti-estrogen drugs are not indicated, but full endocrine work up can eliminate hormonal concerns. Gynecomastia is treated with plastic surgery to excise any glandular component (very fibrotic) and liposuction for fatty components. Large breast may require skin removal and tailoring. ...Read more

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Does pr-negative breast cancer respond to tamoxifen?

It depends.: Tamoxifen is used to treat hormone-sensitive breast cancer. This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective. ...Read more

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Male breast cancer and testosterone supplementation?

Male breast cancer and testosterone supplementation?

What is the question: Asking if testosterone causes male breast cancer or increases its risk? Asking if testosterone should be taken by a man with breast cancer? Should not take hormone supplements if one has male breast cancer without conferring with your oncologist first. ...Read more

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Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Does hormone replacement therapy for menopausal symptoms cause breast cancer?

Increases risk: Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. ...Read more

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Receptor (Definition)

An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more


Dr. Scott Keith
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Hormone (Definition)

A hormone (from greek ὁρμή, "impetus") is a chemical released by a cell or a gland in one part of the body that sends out messages that affect cells in other parts of the organism. Only a little amount of hormone is required to alter cell metabolism. In essence, it is a chemical messenger that transports a signal from ...Read more