Doctor insights on:
Tamoxifen Breast Cancer Treatment
Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read moreSee 1 more doctor answer
Breast Cancer (Female) (Definition)
Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more
Yes: Tamoxifen has been shown to increase the risk of uterine cancer, not unlike estrogen replacement therapy, with an incidence of ~1:500. However, this is almost-always caught at its earliest stage, with very high cure rates. If you compare the benefit of tamoxifen for either treating or preventing breast cancer compared to this risk, the benefit far outweighs the risk. ...Read moreSee 1 more doctor answer
Yes: The chance is about 1% and treatment is hysterectomy. With such a low chance then tamoxifen is worth the risk. A gynecologist needs to keep track of the patient and any unusual bleeding evaluated. There are also other hormone alternatives with less risk. Check with your medical oncologist to see which drug is best for a particular patient. ...Read moreSee 1 more doctor answer
I am on tamoxifen after breast cancer treatment and bilateral mastectomy and now a complete hysterectomy. How much soy in my diet is safe?
Soy is fine in mod: We don't have great data on the effects of soy (and phytoestrogens) on breast cancer. We believe that they act like weak Estrogens and may mimic the effects of tamoxifen (thus reducing risk) but in high doses could have negative effects. So it should be safe to eat some soy but avoid large amounts, like in supplements or shakes, etc. ...Read moreSee 1 more doctor answer
Breast cancer tx: During a breast cancer treatment, you would work closely with your oncology team- including a breast surgeon, medical oncologist and radiation oncologist. All of them will work with you so you can get the best therapy available tailored to your case and to ensure that you can get through the therapy well, cope with those possible adverse events and still able to maintain descent quality of life. ...Read moreSee 2 more doctor answers
Depends on treatment: This is a complex question. Each treatment-surgery, radiation, chemo, hormonal- has it's own uniques set of side effects. In addition, not everyone will experience side effects. The good news is that most side effects can be managed with treatment or medications. Be sure to ask your oncology team questions. ...Read moreSee 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more
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