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Doctor insights on: Tamoxifen Affect Fertility

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Does tamoxifen affect fertility?

Does tamoxifen affect fertility?

Yes: Tamoxifen is most commonly prescribed for the treatment of hormone (+) breast cancer. While tamoxifen may cause birth defects during pregnancy, it actually can increase ovulation, thus increasing fertility. Accordingly, premenopausal women taking tamoxifen for breast cancer treatment must use (nonhormonal forms of) birth control. ...Read more

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Dr. Sean Canale
638 doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


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If my wife was taking tamoxifen for 2 weeks only to improve fertility and we found out she was pregnant, is this going to affect the baby?

If my wife was taking tamoxifen  for 2 weeks only to improve fertility and we found out she was pregnant, is this going to affect the baby?

Tamoxifen: Is not used to improve fertility and can be associate with abnormalities if the woman taking it becomes pregnant. Effective birth control is recommended for women taking tamoxifen and for two mos. After it's use. Why was your wife receiving the drug in the first place? Check with your ob/gyn immediately. ...Read more

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Would nolvadex (tamoxifen) restore fertility in a man with hypogonadatropic hypogonadism caused by a prolactinoma? If so, how long would it take?

Would nolvadex (tamoxifen) restore fertility in a man with hypogonadatropic hypogonadism caused by a prolactinoma? If so, how long would it take?

Possibly: Nolvadex (tamoxifen) is not a common name .It may be an aromatase inhibitor - like anastrozole. Prolactinoma is best treated by removing it if large or tablets of bromocriptine / cabergoline. The urologist determines if is needed as well. ...Read more

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My period was 7 days early for the 2nd month. I'm worried that might signal a change in fertility. I'm in my last yr of tamoxifen. Should I test amh?

My period was 7 days early for the 2nd month. I'm worried that might signal a change in fertility. I'm in my last yr of tamoxifen. Should I test amh?

Tamoxifen: Is an "anti-estrogen" ..(that's why it is so effective in breast cancer treatment (recurrence prevention)..THUS it can "screw up" your cycles big time!! Consult your oncologist for more information! Good Luck Hope this helps! Dr Z ...Read more

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How do I know if the tamoxifen doesn't interact with zeolite ?

Zeolite: Aims to attract "+ charged toxins" and has "no side effects. However, no one has studied what it does to people taking any drug. You can only "know" if there is a specific study that compares: tmx levels +/- zeolite, and benefits at 5 and 10 years. Thus, i'd lay off the zeolite if it were me, but the chance of harm is far-fetched. ...Read more

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I was wondering what would happen if someone took tamoxifen if you didn't have breast cancer?

I was wondering what would happen if someone took tamoxifen if you didn't have breast cancer?

May surprise you but: ...Folks with high risk for breast cancer (without cancer) can take it to reduce their risk. It's not for everybody and should be done under the care of a specialist in the field. Anybody else will get the side effects (hot flashes and increased risk for blood clots and uterine cancer) for no gain at all. ...Read more

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How does tamoxifen actually work?

How does tamoxifen actually work?

Blocks estrogen: Some breast cancer cells have receptors on them that bind to estrogen in order to grow. Tamoxifen acts as an "antagonist" and blocks estrogen from binding to these receptors on the cancer cells by binding to them first. With tamoxifen sitting in estrogen's place, the cancer cell can no longer grow. ...Read more

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Who should avoid taking tamoxifen?

Who should avoid taking tamoxifen?

Blood clots: Pts with a history of blood clots and/or a history of abnormal pap smears should not take tamoxifen. If there is a family history of clotting disorders or uterine cancer, tamoxifen should not be used. ...Read more

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Which side affects does tamoxifen have?

Minimal: Hot flashes most common. Risk of blood clots (like birth control pills). Also, risk of uterine cancer is higher, but still very low. This risk is only seen in post menopausal women. ...Read more

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What are possible reactions to drug tamoxifen?

3 main ones: 1-blood clots/ strokes 2-endometrial carcinoma 3-cataracts hot flashes/ dryness. ...Read more

Dr. Khurram Rehman
1,594 doctors shared insights

Fertility (Definition)

Fertility refers to the ability of a woman to conceive a child, or to the ability of a man to ...Read more