Doctor insights on:
Taking Methotrexate And Nsaid Together
Yes: NSIDs can be taken with Methotrexate. With or without Methotrexate, NSAIDs have many possible side effects and need to be used carefully. Gastrointestinal issues such as ulcers/gastritis can occur. Studies continue to show NSAIDs are associated with increased risks of cardiovascular side effects such as heart attacks and strokes. Routine labs are needed to watch for other side effects of both meds ...Read moreSee 1 more doctor answer
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
6y/o will jia nsaids failed to work now on methotrexate but having a lot of side effects. Is there another medicine that works well with jia?
Tnf inhibitors: Tnf inhibitors work well.Get a more detailed answer ›
What is the best treatment for chronic recurrent multifocal osteomylitis; nsaid, s don't work? Is methotrexate an appropriate treatment for a 12 yr old
What is an analgesic drug other than nsaids ( because of interaction with methotrexate) for rheumatoid arthritis and stronger than paracetamol ?
Child has JRA on methotrexate remicaid NSAID just got off a round of steroids knee still really swollen in similar situations what is next step?
See her doctor: First I wish your child recovery/control of her RA symptoms, given the bit complex condition especially with the potent drugs she is on and the round of steroids given lately, you need to stick to the regimen and get back to the treating physician, he/she can judge what is the next step, or seek a second opinion if you can, that's your right, goodluck ...Read more
Is it safe to get a tattoo while on methotrexate for psoriatic arthritis? Blood levels are all good. Only NSAID is 7.5 daily of Mobic (meloxicam).
Not that I know of: I don't believe there are any significant interactions between those two drugs ...Read more
What are my chances of getting liver disease while taking arava (leflunomide) and methotrexate together?
See details: Studies of this combination have shown increased risk of liver disease over taking just one of these meds alone. The exact risk is open to debate. I personally never prescribe this combination of meds although other rheumatologists do. ...Read more
Maybe: Methotrexate is used in (many cancers) chemotherapy, rheumatoid arthritis, ectopic pregnancies, and molar pregnancies. Misoprostol is used in stomach ulcers (its FDA approved use), bleeding after a delivery of a baby,and bleeding after a miscarriage. We also sometimes use it in place of D&C to prevent an incomplete miscarriage or in term pregnancies to expel a retained placenta. ...Read more
Is this ok to give pt of severe fever(for the last 24 hrs) NSAID, dexamethasone and paracetamol together ?
A child is on methotrexate 12.5mg once weekly for JRA. She was prescribed amoxicillin for a sinus infection. Is it okay for her to be taking these together? I saw that there is a potential for interaction between the two.
Yes but not a major: Yes there is an interaction but not at the doses we use for arthritis. the amoxicillin can increase the level of methotrexate. This is a problem with the high anti-cancer doses we use to treat malignancy. But you may want to hold the methotrexate until the sinus infection clears. ...Read moreSee 1 more doctor answer
My mother have RA she is taking methotrexate and ibuprofen as analgesic are they safe together ? There is any dangerous drug-drug interaction ?!
Safe: I have seen virtually no issue in my patients who have combined these 2 meds. ...Read more
Question for rheumatologists : we can give nsaids and low dose corticostiroids together for patient on RA waiting for dmards to take its efficacy ?
Yes and no: This type of combination is common, but since each class of medication increases risk for GI side effects, caution is important. Using a medication such as Omeprazole to protect the stomach is a good idea, and minimizing the dose and duration of the corticosteroid is very important. ...Read moreSee 1 more doctor answer
Can I drink zipsor and doxycycline hyclate together? Also get methotrexate injection once a week, is there any drug interactions?
Hello, are these two drugs (Methotrexate and Misoprostol) used together along with a IUD in the treatment of uterine fibroid?
Fibroid treatment: Uterine fibroids are not treated with methotexate. Cytotec (misoprostol) has been used to induce abortion and decrease menstrual blood flow but is not able to shrink fibroids. I have never heard of an IUD being used to treat uterine fibroids. Consult with your gynecologist is your fibroids are causing pain or excessive bleeding. ...Read more
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