Top
40
Doctor insights on: Taking Methotrexate And Non Steroidal Anti Inflammatory Together

Share

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


3

3
What is the treatment for non steroidal anti inflammatory overdose?

What is the treatment for non steroidal anti inflammatory overdose?

See a Doctor !: Aspirin or acetylsalicylic acid (asa) is quite powerful . Overdose affects you blood clotting. It can also affect your blood pH (acidity) which is extremely dangerous. Nsaids are in the same general description ...Read more

4

4
Do SSRI antidepressants have anti inflammatory and antipyretic effects??

Do SSRI antidepressants have anti inflammatory and antipyretic effects??

They: may affect bleeding times and may have analgesic effect, but not anti inflammatory. ...Read more

5

5
Why're non-steroidal anti-inflammatory drugs such as meloxicam considered contraindicated in renal disease?

Why're non-steroidal anti-inflammatory drugs such as meloxicam considered contraindicated in renal disease?

They hurt the kidney: Nsaids interfere with the internal regulation of blood flow in the kidney. Using them reduces renal blood flow and decreases kidney function. ...Read more

6

6
Is baby aspirin used for anti inflammatory?

Not really: Aspirin at low doses has the ability to decrease the stickiness of your platelets and is often used to reduce chances of a stroke or heart attack. Aspirin does have anti-inflammatory properties, but its association with liver damage/failure and brain damage in kids (reye syndrome) led to rare use under the age of 16. ...Read more

See 1 more doctor answer
9

9
What do you think of the combination of celebrex (celecoxib) and sulfasalazine to treat RA beside taking other medications such as methotrexate and Enbrel ? Instead of Norco or motrin or tramadol

What do you think of the combination of celebrex (celecoxib) and sulfasalazine to treat RA beside taking other medications such as methotrexate and Enbrel ? Instead of Norco or motrin or tramadol

Depends on severity: It depends on the severity and activity of your RA. Enbrel and Methotrexate are great drugs if you have active. If it is not active Celebrex (celecoxib) and sulfasalazine are alternatives. We discourage people to use narcotic painkillers for non cancer pain for the long term since it is very addictive and people become tolerant for the doses and expect increasing doses ...Read more

See 2 more doctor answers
10

10
What specific cox2 inhibitors are safe anti-inflamatory & analgesics for patients with*favism* and gastritis?

What specific cox2 inhibitors are safe anti-inflamatory & analgesics for patients with*favism* and gastritis?

No Celebrex!: Celebrex (celecoxib) is contraindicated in somewhat with g6pd because it is a sulfa drug. I otherwise don't know the answer to your question, but wanted to make sure you knew about this, given the content of a previous answer. ...Read more

See 1 more doctor answer
12

12
Can i take anti inflammatories along with metronidazole and amoxicillin?

Can i take anti inflammatories along with metronidazole and amoxicillin?

Yes: Yes, as prescribed or otc in moderation unless you have some systemic condition contraindicating the use of antiinflammatories. Always avoid alcohol while on metranidazole. ...Read more

13

13
Can i take anti inflamatory medicine ( refalen) with the new instaflex?

Can i take anti inflamatory medicine ( refalen) with the new instaflex?

Caution: Mixing is borderline safe as instaflex does have willow bark-- an Aspirin product, so take care. Take Relafen (nabumetone) with food and a full glass of liquid the main ingredients of instaflex glucosamine sulfate ( 1, 250 mg) other ingredients include: methylsulfonlylmethan (msm) white willow bark extract ginger root concentrate 4:1 boswella serrata extract turmeric root extract cayenne hyaluronic acid. ...Read more

15

15
Does taking medications such as anti depressants, contraceptive pill and panadol (acetaminophen) harm my biliary atresia liver?

Does taking medications such as anti depressants, contraceptive pill and panadol (acetaminophen) harm my biliary atresia liver?

Yes: If you have an impaired liver, then you have to be careful about almost all drugs. Most are processed in the liver, and special consideration and dosing are given to people with liver disease. ...Read more

See 2 more doctor answers
16

16
Does benzonatate have anti inflammatory?

Does benzonatate have anti inflammatory?

No: It is used to suppress the cough reflex n the lungs and air-passages. ...Read more

18

18
Can u use an anti- inflammatory (NSAIDs) throat spray along with ibuprofens tablets ?

One or the other: It`s unnecessary and not advisable. Oral NASAIDS get into most tissues-local sprays are local but with some small systemic absorption. Don`t do both. ...Read more

19

19
Which is more affective pain management of a gouty foot flare-up, Naproxen or Celebrex (celecoxib)? (along with Colchicine) Allipurinol already prescribed.

Probably naproxen: Naproxen has been used for many years to treat acute episodes of gout-colcichine has been used longer but has more side effects if pushed.Celebrex (celecoxib) is an N SAID too but used more for having less gastrointestinal side effects. So the person who knows best with your history is the prescribing. Doctor. ...Read more

See 1 more doctor answer
20

20
Are topical pain relievers like ketoprofen safe and effective?

Are topical pain relievers like ketoprofen safe and effective?

Effective yes,safe?: They may get absorbed and cause the same possible side effects, even though absorption may be much less than p.O.. ...Read more

See 1 more doctor answer
21

21
What is the definition or description of: Non steroidal anti inflammatory overdose?

What is the definition or description of: Non steroidal anti inflammatory overdose?

NSAIDs: NSAIDs do have side effects and therefore the FDA recommends the lowest effective dose for the shortest period of time. In rare cases overdoses may occur. The biggest concern is an acute injury to the kidneys. Some medications such as diclofenac in high doses may affect the liver. Aspirin may also be considered an NSAID and in high doses may cause GI upset and ringing of the ears. ...Read more

22

22
How will non steroidal anti inflammatory overdose affect my health going forward?

How will non steroidal anti inflammatory overdose affect my health going forward?

Kidney and stomach: These are the two areas most affected. Nsaids can cause erosion of the stomach lining and lead to ulcers and bleeding. They can also cause acute renal failure, especially if taken in large doses. If everything looks fine after an overdose then there shouldn't be any long-term problems. ...Read more

See 1 more doctor answer
23

23
Why're non-steroidal anti-inflammatory drugs such as meloxicam considered contraindicated in renal disease?

They hurt the kidney: Nsaids interfere with the internal regulation of blood flow in the kidney. Using them reduces renal blood flow and decreases kidney function. ...Read more

24

24
Are there non-steroidal anti-inflammatory drugs to treat diabetic nephropathy?

Are there non-steroidal anti-inflammatory drugs to treat diabetic nephropathy?

NO: There are no drugs that treat diabetic nephropathy per se. Diabetic nephropathy is not a curable condition. Slowing it down can be achieved by several maneuvers including controlling diabetes and hypertension well and using drug group called ace inhibitors or arb under a close supervision of a doctor since these drugs may have significant side effects. ...Read more

See 1 more doctor answer
26

26
Can steroid anti-inflammatory medications cause GI upset?

Yes: Corticosteroids an cause gastric pain, gastric ulcers, gastrointestinal cramps and bleeding. ...Read more

See 1 more doctor answer
29

29
If my back pain responded well to strong steroids and anti inflammatory meds does that mean i would benefit from those injections that numb the nerves?

Get 2nd opinion: With cardiac catherization, endoscopy procedures done, and taking otc pain, and prescription blood pressure meds, you may benefit from seeing an osteopathic doctor to evaluate your pain, and musculoskeletal issues further, before using injectables. Steroids and anti-imflammatories are not safe to use long term, because of their side effect profiles.So, look at some non-drug alternatives 1st. ...Read more

See 1 more doctor answer
32

32
Does steroid anti-inflammatory medication influence the eligibility for mentoplasty? I suffer from a rheumatic disease called vasculitis. My medication regimen consists of steroid anti-inflammatory drugs. How does this affect the outcome of mentoplasty su

Still Possible: Steroids decrease our ability to heal and fight infection. Depending on the dose, you still may be able to have a mentoplasty. I would consult with a well respected facial plastic surgeon who can coordinate things with your rheumatologist. ...Read more

See 1 more doctor answer
33

33
Does steroid anti-inflammatory medication influence the eligibility for mentoplasty? I suffer from a rheumatic disease called vasculitis. My medication regimen consists of steroid anti-inflammatory drugs. How does this affect the outcome of mentoplasty su

Healing: Steriods generally slow down the healing process as they affect the biosynthesis of collagen. Collagen is a major protein made by the body in healing and forming scars. You will need to discuss this with your surgeon who may or may not want you to be off the steroid for a period of time around the surgery. ...Read more

See 1 more doctor answer
34

34
Is there a steroid component in methotrexate.

Is there a steroid component in methotrexate.

No: No steroid component in Methotrexate. In different conditions and for flares steroids are added to Methotrexate that is more of a chronic/ maintenance drug. ...Read more

35

35
I started imuron for scleritis at 50 mg in am and 50 mg in pm and is this good drug for scleritis. No luck w/steroids and methotrexate.

I  started imuron for scleritis at 50 mg in am and 50 mg in pm and is this good drug for scleritis. No luck w/steroids and methotrexate.

Cautiously yes: Scleritis is painful, and can have severe complications if not treated. Treatment often involves strong immune suppressant medications like Imuran (azathioprine). These drugs can also have serious side effects. You must be monitored closely by an ophthalmologist and a rheumatologist during treatment and afterwards. Auto-immune diseases such as lupus may cause scleritis. ...Read more

See 1 more doctor answer
37

37
While being on steroids-2.5mg, sazo-500mg (6/day), methotrexate-15mg, is it right to get a flareup of uc?My grandmother died of cervial cancer will i get

UC/cancer: You can still get a flare despite being on the meds listed. It depends on the severity and extent of your illness. It could have been worse probably if you were not taking these meds, though. Uc doesn't cause cervical cancer. We know today that this is caused by hp virus (human papiloma). It's a sexually transmitted disease. ...Read more

40

40
Have arthritic knees take methotrexate get steroid shots in knees to walk got them 2 1/2 mos ago how often for how long safely hurt now trouble walkin?

Have arthritic knees take methotrexate get steroid shots in knees to walk got them 2 1/2 mos ago how often for how long safely hurt now trouble walkin?

Knee arthritis: If you do not want knee replacement or are not a candidate for any given reason, there is a procedure called Genicular nerve ablation which will relieve the pain for about a year at a time. Try to find a pain physician in your area. Much better than getting steroid injections on a regular basis. It makes your knee joint numb so you won't feel any pain and is a very safe and effective procedure. ...Read more

See 1 more doctor answer

Antiinflammatory (Definition)

Inflammation is a condition of swelling that may or may not be associated with pain. Anti-inflammatory are medications that block the cause of this condition. Medications include ibuprofen, naproxen, and celecoxib. Steroids (cortisone) are ...Read more


Dr. Robert Lowe
340 doctors shared insights

Rheumatrex (Definition)

Rheumatrex ...Read more