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Doctor insights on: Taking Methotrexate And Having Wrong Site Surgery

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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M31, why my surgeon prescribed arthrotec (diclofenac and misoprostol) 50mg for 5 days after hernia surgery. Its giving me mild pain in stomach, what alternative I may take.

M31, why my surgeon prescribed arthrotec (diclofenac and misoprostol) 50mg for 5 days after hernia surgery. Its giving me mild pain in stomach, what alternative I may take.

For pain: This is most likely for post-op pain. If you are having stomach problems from it, stop taking it. Ask your surgeon for a different type of pain medication. They should take your call (or whomever is covering for them) even on the weekend. ...Read more

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Obinutuzumab is part of my chemo treatment. Should I be exercising while taking this med ?

Obinutuzumab is part of my chemo treatment. Should I be exercising while taking this med
 ?

Yes exercise is good: There is no reason to stop your normal life activities. Exercise is almost never harmful if you have the energy and the desire to Exercise! ...Read more

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I experience nausea daily, and i don't remember having this before taking antibiotics about 1.5 years ago, could my stomach still be off from this?

I experience nausea daily, and i don't remember having this before taking antibiotics about 1.5 years ago, could my stomach still be off from this?

Lots of causes: There are lots of causes of nausea. For example it can be from pain medications women take for their period which irritates the stomach. Antibiotics from 1.5 year ago seems less likely. Have you have been experiencing it from the time you took the antibiotics?. See your physician for a full evaluation. You shouldn't have daily nausea. ...Read more

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My mom has RA will undergo in this two weeks hip replacment surgery..so she should stop taking adalimumab(humira) and methotrexate for surgery ?

My mom has RA will undergo in this two weeks hip replacment surgery..so she should stop taking adalimumab(humira) and methotrexate for surgery ?

Probably yes: The operating surgeon will direct you in the correct answer. These medicines may change immune system or risk of bleeding, but only the surgeon has the experience to direct your mom for best outcome. When to stoop and restart is crucial to allow the meds to continue controlling the underlying disease. ...Read more

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I have been prescribed naproxen 500 mg and am a light smoker, what are the risks of smoking while taking this med?

I have been prescribed naproxen 500 mg and am a light smoker, what are the risks of smoking while taking this med?

Smoking: The main risk of nsaids is slightly higher blood pressure and stomach upset. The main risk to your health, however, is continuing to smoke, rather than any ill effect of the drug itself. High blood pressure, increase risk of heart disease, stroke, lung, colon, bladder, mouth and esophageal cancer as well as COPD and emphysema should all get your attention more than the risks of nsaids. ...Read more

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After two surgeries I have to take B12 shots monthly but still have no energy. Amount of sleep and diet seem unrelated. Can my humira (adalimumab) be causing this?

After two surgeries I have to take B12 shots monthly but still have no energy. Amount of sleep and diet seem unrelated. Can my humira (adalimumab) be causing this?

Yes it can: Humira (adalimumab) can cause "lack of energy" feeling, but not very common. I assume that you had gastric surgeries? Since you food intake is significantly reduced after the surgeries, this can itself cause the lack-of-energy feeling for quite some time until you body has the time to readjust. Also, thyroid dysfunction as well as depression can cause this feeling ..So, onsult your doc.. ...Read more

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Mastectomy 3 weeks ago. More surgery this Tuesday. Can taking 2 500 mg ibuprofen this past week cancel this surgery?

Mastectomy 3 weeks ago.  More surgery this Tuesday.  Can taking 2 500 mg ibuprofen this past week cancel this surgery?

Depends on surgeon: Depending on what the surgery is and your surgeon's judgment, your surgery could be cancelled. Even a small amount of ibuprofen COULD increase your chances of having excessive bleeding during or after surgery. You really should let your surgeon know now rather than on the morning of surgery. It's much easier, safer, and less expensive to all to reschedule surgery than to cancel it the morning of. ...Read more

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I take 25mg of hydroxyzine along with 25 mg of amitryptyline for my ic problems....Have been for years what side effects might happen by doing this an?

I take 25mg of hydroxyzine along with 25 mg of amitryptyline for my ic problems....Have been for years what side effects might happen by doing this an?

Constipation: Both has some anti-cholinergic and drowsy effect. Thus constipation and faster heart beats may be some of the side effects. If you are feeling fine otherwise, you shouldn't worry over them. ...Read more

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Injured shoulder 20yrs ago.Since been having recurring pain, limited motion. Gp suggests cortisone shot. I feel too many risks. Any other options?

Injured shoulder 20yrs ago.Since been having recurring pain, limited motion. Gp suggests cortisone shot. I feel too many risks. Any other options?

Can C osteopathic Dr: A second opinion with an osteopathic physician, who can do a complete musculoskeletal evaluation, and treatment may prove wise, as that would increase your rom, and also bring relief. So, you may not need as many cortisone shots, or not need them at all, if your rom is improved. Also, it may allow you to sleep better, and improve your quality of life. ...Read more

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I have been prescribed 20mg of prednisone. 5 days, take 3 pills 1time/day. Prescribed to me because my bronchitis is not going away after 7 days of taking 10 day course of Avelox. I know there are many possible side effects. I am experiencing several, bu

I have been prescribed 20mg of prednisone. 5 days, take 3 pills 1time/day.  Prescribed to me because my bronchitis is not going away after 7 days of taking 10 day course of Avelox.
I know there are many possible side effects. I am experiencing several, bu

Prednisone: Can cause a lot of side effects, especially at higher doses. For some, 60 mg at one time can cause feelings of nervousness, mood swings, insomnia etc, as well as elevations in blood sugar and blood pressure. If you are experiencing these, you could try splitting the dose in half and take it twice per day, or if that is still causing side effects, you may need to take a lower dose.Talk to your Dr. ...Read more

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I've had left side pelvic pain, cramping and bleeding with restarting birth control August 2nd, what what be a good pain reliever to take?

I've had left side pelvic pain, cramping and bleeding with restarting birth control August 2nd, what what be a good pain reliever to take?

Pelvic pain: Pelvic pain is complex as there are several organs in the pelvis. The ovaries, fallopian tubes, uterus, cervix, bladder, appendix, intestines, colon and rectum can all be the source. Pelvic pain requires and examination to help organize the evaluation. Restarting birth control should not cause pain. Ibuprofen is commonly used for pelvic pain ...Read more

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What should my concerns be if I have RA and have been given a reclast (zoledronic acid) injection? Dexa scan -2.6 take zocor, plavix currently RA not active-not taking meds for it, have had methtrexate or embril in past, due to heart attack have lost w

What should my concerns be if I have RA and have been given a reclast (zoledronic acid) injection? Dexa scan -2.6  take zocor, plavix  currently RA not active-not taking meds for it,  have had methtrexate or embril in past, due to heart attack have lost w

Weel : Weel for what i can understand you hade rheumatoid arthrtis that was treated with embrel and Methotrexate , and at this time you are in remission . Congratulations on your acomplishment on the weight loss and the excersice program . Taht a winner you don t have to be wrried or concern about the Reclast (zoledronic acid) , pt wit RA have a higher risk of developing osteoporosis, and are the ones that need to be treated . As far as the side effects , is like with every medication, or any activity in life . And the risks are undersurveillance and known , and accepted by the authorities in the department of health as adecuate for use. So you received Reclast (zoledronic acid) , because there was an indication that justifies its use , and the likelihood of an adverse effect is low. There is no interaction between the Reclast (zoledronic acid) and the rheumatoid artjhrtis. ...Read more

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I am having foot surgery for a dislocating tendon and the dr prescribed pain meds but no antibiotics? Shouldn't I have antibiotics after surgery?

I am having foot surgery for a dislocating tendon and the dr prescribed pain meds but no antibiotics? Shouldn't I have antibiotics after surgery?

Post op: Antibiotics are not typically given after surgery for what sounds like a planned, elective surgery which did not include an infectious aspect to it. Ask your surgeon's office too. He/she will be happy to explain their protocol regarding your surgery ...Read more

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I'm taking prednisone eye drops cause i had lasik eye surgery. Is that going to mix bad with Advil (ibuprofen) I am taking for my knee taking from a recent injury?

I'm taking prednisone eye drops cause i had lasik eye surgery. Is that going to mix bad with Advil (ibuprofen) I am taking for my knee taking from a recent injury?

No problem: there is trivial absorption of the topically applied prednisolone drops into the systemic circulation. So there will be no mixture or interaction and you can treat each condition separately as prescribed. ...Read more

Dr. Robert Lowe
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Rheumatrex (Definition)

Rheumatrex ...Read more