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Doctor insights on: Taking Methotrexate And Having Major Surgery

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Why do I need to stop methotrexate & arava (leflunomide) before alif surgery? I can't take it for 2 months after, why?

See details: Two months is an unusually long period to hold Methotrexate after surgery. Three weeks is more the usual but it is ultimately up to your surgeon. ...Read more

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Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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My mom has RA will undergo in this two weeks hip replacment surgery..so she should stop taking adalimumab(humira) and methotrexate for surgery ?

My mom has RA will undergo in this two weeks hip replacment surgery..so she should stop taking adalimumab(humira) and methotrexate for surgery ?

Probably yes: The operating surgeon will direct you in the correct answer. These medicines may change immune system or risk of bleeding, but only the surgeon has the experience to direct your mom for best outcome. When to stoop and restart is crucial to allow the meds to continue controlling the underlying disease. ...Read more

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Treatment for a cervical pregnancy, just took third shot of methotrexate. If hCG numbers don't go down by tuesday they want to do surgery. Hcg 1660?

Treatment for a cervical pregnancy, just took third shot of methotrexate.  If hCG numbers don't go down by tuesday they want to do surgery. Hcg 1660?

Ectopic/cervical: You have a rare type of ectopic pregnancy which the md is using a first line of rx with Methotrexate in less than 8 weeks of gestation hopefully. If the HCG is still elevated the surgery is necessary to remove the pregnancy before it ruptures in the cervix through the uterine or descending vaginal artery. ...Read more

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Can i take cold medication if i'm taking methotrexate. ?

See below: As a good rule of thumb, if you have an infection, you would want to leave off your Methotrexate and Imuran (azathioprine) and when the infection resolves, you can resume them. ...Read more

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Is it safe to have a gin and tonic when taking methotrexate?

Maybe: Methrotrexate can be toxic to the liver. Excess alcohol is also toxic to the liver. In general alcohol use should be avoided when taking Methotrexate to avoid any possibility of liver damage. ...Read more

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What are the top 3 things that I should be careful of/expect while taking a methotrexate for Crohn's disease?

Many side effects: Probably the three most common side effects include skin- rash hair loss or sores in the mouth, abnormal liver enzymes and possible effects on the blood, lowering blood and platelets counts. ...Read more

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What happens if you stop taking methotrexate for your arthritis?

What happens if you stop taking methotrexate for your arthritis?

Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard. ...Read more

Dr. Robert Lowe
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Rheumatrex (Definition)

Rheumatrex ...Read more