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Doctor insights on: Taking Antihistamines Everyday

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Is taking antihistamine everyday bad for you in the long term? Will my immune system get impaired?

Is taking antihistamine everyday bad for you in the long term? Will my immune system get impaired?

No and no.: There are no known longterm sequellae from antihistamines. I would stick with the long-acting, non-sedating ones, such as Allegra and Claritin, (loratadine) since the short-acting ones can make you drowsy. Antihistamines do not affect the immune system in any measurable way. Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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My husband is always suffering fron rhinitis and always taking loratadine antihistamine almost everyday. Is it safe? Is there some other med that will cure his rhinitis?

My husband is always suffering fron rhinitis and always taking loratadine antihistamine almost everyday. Is it safe? Is there some other med that will cure his rhinitis?

Alternatives: Here are some options Taking loratadine long term is safe. He could also try other antihistamines. Steroid nasal sprays are also safe to use long term and often more effective. Allergy testing may reveal avoidable triggers. The only treatment that even comes close to a cure is allergy immunotherapy. See an allergist to find the best option for your loved one. Read more

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Will taking antihistamines at bedtime reduce its effects the second day?

Will taking antihistamines at bedtime reduce its effects the second day?

Antihistamines: At night should not have any effect on how well they work the next day. People don't get desensitized to antihistamines, though a lot think they do. If you are taking Benadryl (diphenhydramine) at bedtime, don't expect it to take care of you the next day though, as it is a short acting medication. Read more

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Can you get false negative results in food intolerance test if taking antihistamine?

Can you get false negative results in food intolerance test if taking antihistamine?

Food testing: Food intolerance testing is not scientifically based, meaning this is not a good test. The best test for food intolerance is to eliminate one food at a time to see if symptoms improve. Food allergy testing (specific IgE testing via blood or skin) is a scientifically validated test and is used for patients with history of hives, itching, swelling, wheezing, coughing, vomiting, etc soon after eating Read more

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Can I die by taking too many antihistamine tablets?

Can I die by taking too many antihistamine tablets?

Taking lethal over: Dose would do that. Lethal overdoses of antihistamines are rare. Are you considering taking an overdose of antihistamines? If so, please get help right away. You can use national suicide hotlines 24/7 at 1-800-suicide (1-800-784-2433) or 1-800-273 – talk (1-800-273-8255). If you have accidentally taken too many antihistamines please contact 1-800-222-1222 (poison control hotline). Take care. Read more

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Does taking antihistamine help with eczema?

Does taking antihistamine help with eczema?

Yes you scratch less: Antihistamines are one of the important medications that we use for eczema or atopic dermatitis. The condition starts with itching, which leads to scratching, which causes a rash to develop, and then there is more itching and a vicious cycle ensues. Antihistamines are used to decrease the itching. Sedating antihistamines can be used at night to help decrease scratching while asleep. Read more

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What happens if I smoke weed while taking antihistamines?

Yes: I am not going to judge whether smoking weed is ok or not but if smoking weeds makes you drowsy and you are taking a sedating antihistamine such as Benadryl (diphenhydramine) or atarax, the sedating effects may be additive. Antihistamines, especially the non-sedating ones, usually have a good safety profile. Read more

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Can I take an antihistamine while taking benzonatate 200 mg?

Can I take an antihistamine while taking benzonatate 200 mg?

Yes: Generally yes. However, benzonatate can cause drowsiness. The first generation antihistamines (such as benadryl, (diphenhydramine) doxepin, chlorpheniramine, and hydroxyzine), can also cause drowsiness. Hence, the affect could be additive. With that in mind, you might want to consider taking a second generation antihistamine such as cetirizine, xyzal, fexofenadine, etc. Read more

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What can I do about water weight from taking antihistamines daily? It happens with ALL of the antihistamines.

Not expected: Antihistamines do not cause water retention. However the older generation antihistamine may occasionally slow down bladder emptying if this is what you meant. Read more

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I gave expired antihistamine syrup to my 30 months old son incidentally...Is it dangerous? What s the side effect on him?

I gave expired antihistamine syrup to my 30 months old son incidentally...Is it dangerous? What s the side effect on him?

Expired drugs: There should be no side effects as expiration is usually based on loss of drug effectiveness. Drug companies err on the side of shortening times to expiration. Actually many drugs are effective long after expiration dates. Expired drugs are commonly used effectively by volunteer organizations when no other drugs are available. Relax! Read more

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Now knowing that older antihistamines like hydroxyzine make you gain weight, how soon after I stop taking it will I start to lose the weight?

Now knowing that older antihistamines like hydroxyzine make you gain weight, how soon after I stop taking it will I start to lose the weight?

Depends: Once your appetite returns to normal, you will have to eat less (particularly carbs) and exercise more to lose the weight which was gained. The speed of loss depends on how much less you eat and how much more you exercise. Read more

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2 days of hive outbreak has gotten worse - unsure what caused it but this is not the 1st time. Been taking off-brand antihistamine to no effect. Help!

2 days of hive outbreak has gotten worse - unsure what caused it but this is not the 1st time. Been taking off-brand antihistamine to no effect. Help!

See a dermatologist: May be allergy. Maybe not. Zyrtec (cetirizine) (cetirazine) OTC 10mg. May need 2 or 3. Larger dose can make you sleepy. If severe, add prescription hydroxyzine 25mg at bedtime. If present over 6 weeks it is chronic urticaria which is usually not allergy. Avoid aspirin, alcohol. Beware of any and all pills or meds of any kind. Need precise diagnosis for best result. Read more

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Is Flixonase an antihistamine?

Is Flixonase an antihistamine?

Steroid Nasal Spray: Flixonase or Flonase (fluticasone proprionate) is a steroid nasal spray commonly used to treat allergic rhinitis by decreasing the allergic inflammation in the nasal mucosa. It is not an antihistamine. Read more

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Is there an antihistamine cream?

Is there an antihistamine cream?

Yes, but avoid: Benadryl (diphenhydramine) cream is available. While some people find temporary relief for insect bites with this, in general it is not very effective compared to other antihistamines taken as pills or tabs. For generalized rash, it really doesn't make sense. Read more

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Does antihistamine make you drowsy?

Older ones do: First generation antihistamines (benadryl, clor-pheramine, atarax) cross the blood brain barrier and cause lethargy. Second generation (allegra, claritin, zyrtec, xyzal, (levocetirizine) clarinex) cause the blood brain barrier at a much lesser amount and more targeted to the h1 receptor. Read more

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Can you use antihistamine and wine?

Can you use antihistamine and wine?

Not a good idea: Antihistamines (especially the older ones such as benadryl) can cause drowsiness and impairment and this can be worsened by the effect of alcohol even at regular doses. There are other allergy medications available that can be taken if a glass of wine is desired. Read more

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Is it ok to take antihistamines with?

With what?: If you are thinking about drinking alcohol, do not do it. Antihistamines might potentiate the effect of alcohol. Read more

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Dr. Paul Carter
638 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more