Doctor insights on:
What are normal prograf levels for liver transplant patients and what ios the avg medication adjustment time, if any?
6-12: Talk to your transplant pharmacist. After a solid organ transplant you need conselling from a transplant pharmd. The level of tacrolimus is not the only criteria to be concerned about. They will talk to you about interactions between medications and how frequent to expect any medical changes. Your team of surgeon, hepatologist, pharmd and psychologist will all help as well as your nurse practi. ...Read more
I've had a kidney transplant in the year 2005, i've been on tacrolimus since 2008. Can you please tell me the major side effects of the drug ?
Adverse effects: Some side effects include headache, elevated blood pressure, insomnia, rash, metabolic abnormalities, diarrhea, abdominal pain, nausea, constipation, low red or white blood cell count, liver and kidney problems, infection, diabetes mellitus, and weakness. ...Read moreSee 2 more doctor answers
Autoimmune suppressi: Tacrolimus or Prograf or Advagraf is an immunosuppressive drug used mainly in organ transplant to reduce organ rejection. It has also been useful in atopic eczema and in severe uveitis ( Inflammation of the colored portion of the eye ) Side effects can be severe. Patient must be under specialty care throughout the treatment. Topical use can cause irritation and burning sensation used for eczema ...Read more
Depends: Tacrolimus is a calcineurin inhibitor and is the most widely-used immunosuppressive medication in the U.S. for organ transplant recipients. It is a twice-a-day drug. Because it has a narrow therapeutic index, one needs to have its blood level monitored as excessively high levels can cause nephrotoxicity (can cause kidney failure). ...Read moreSee 1 more doctor answer
Two types : First those related to immunosuppression. It affects t cell immunity so you can get viruses (like CMV and ebv) and rarely lymphoma. Second idiosyncratic side effects including elevated creatinine, high blood pressure and high potassium. Seizures, tremor. Hair loss. Despite all of these side effects, one of the best drugs for transplant patients. Can be used very safely. ...Read more
Nephrotoxicity: Most concerning long-term adverse effect of Program (tacrolimus) is nephrotoxicity (damage to the kidneys). The drug has a narrow therapeutic index and therefore the blood level of the drug is often monitored to avoid side effects. Other known side effects include tremor, elevated blood pressure, elevated blood glucose, and hair loss. ...Read more
Wich is better in general, prograf or cyclosporin? For the kidney, i really want the best for my kidney and my health, please?
Taking Prograf XL, 0.5 mg twice daily. Tacrolimus level <2 ng/ml (ref: 5-20 ng/ml). What can cause my tacrolimus to be below the desired range?
Drug levels: Other medications can affect the level of a medication, and sometimes there is lab error. Speak with your specialist who ordered the lab test to determine if repeat or follow up is necessary ...Read more
Skin cancer: Prograf suppresses the immune system and does make one more prone to skin cancer. Since the vast majority of skin cancers remain localized, one need not worry about rapid spread. It is a very good idea to practice good sun sense if you are immunosuppressed. This would include coverup clothing and sunscreens when outdoors. ...Read more
Tacrolimus: is used prophylactically (with other medications) to help prevent rejection of transplanted organs. Some side effects include ^'ed suseptibility to infections and certain malignancies. Your pharmacist can provide you a complete list of potential side effects. ...Read moreSee 1 more doctor answer