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Doctor insights on: T Cell Lymphoma

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What is hepatosplenic t cell lymphoma?

What is hepatosplenic t cell lymphoma?

A Rare Lymphoma: Hstcl is a rare cancer of the the white blood cells. It usually affects young men with a history of immunosuppression for other diseases like inflammatory bowel disease (uc and/or crohn's) or after an organ transplant. The bad cells usually grow in the liver, spleen and bone marrow. It is treated with chemotherapy and possibly a bone marrow transplant. It unfortunately can be difficult to cure. ...Read more

Dr. Michael Thompson
1,755 doctors shared insights

Lymphoma (Definition)

A malignancy developing in the lymphocytes of lymph glands. They present as an enlarging node that continues to grow and then ...Read more


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What is large cell t cell lymphoma exactly?

What is large cell t cell lymphoma exactly?

Cancer of T-cells: T-cell non-hodgkin's lymphoma is a cancer of the t type (subset) of lymphocytes. Other types of lymphocytes include b cells. Other lymphomas include over 40 subtypes including hodgkin's lymphoma. ...Read more

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Which is worse, b cell lymphoma or t cell lymphoma?

Which is worse, b cell lymphoma or t cell lymphoma?

T-cell NHL: The prognosis for t-cell non-hodgkin's lymphoma (nhl) vs. B-cell nhl depends on multiple factors, but in general t-cell nhl has a worse prognosis. One reason is that b-cell, cd20+ nhl can be treated with the anti-cd20 monoclonal antibody Rituximab in addition to chemotherapy. We currently don't have such an effective, low toxicity antibody (biologic treatment) for t-cell nhl. ...Read more

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How long can mantle cell lymphoma go undetected? Where does mantle cell lymphoma show up?

Months, anywhere: Mantle cell lymphoma is a rare subtype of non-hodgkin's lymphoma. It usually grows relatively slowly and might take several weeks to a few months to develop. It most commonly presents in the lymph nodes, the blood, and the spleen although it can also present anywhere in the G.I. Tract from the stomach down to the colon. ...Read more

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Wat is mantle cell lymphoma?

Mantle cell lymphoma: Is a less common b-cell disease in the non-hodgkin's lymphoma group. It tends to be advanced stage when diagnosed, and can have a propensity to involve both the gut and skin. About 20% of cases behave indolently, and treatment is quite effective at diagnosis. Late relapses are common, and treatment is more challenging the second time around. ...Read more

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How do stem cell transplants actually cure leukemia cancers?

How do stem cell transplants actually cure leukemia cancers?

Chemo and more: There are two types of transplants but the most common type used for leukemia is called allogeneic where the stem cells come from a donor. As part of the transplant the patient gets chemotherapy, sometimes in very high doses which treats the leukemia. The new immune system from the donor can also attack the leukemia cells and lead to a cure. This is called the graft-versus-leukemia effect. ...Read more

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Mantle cell lymphoma - is that like a hodgkin's?

Mantle cell lymphoma - is that like a hodgkin's?

Non hodgkin's: Mantle cell lymphoma is a subset of non hodgkin's lymphoma. Under microscope, it looks like clusters of small size of lymphoid cells mimicking appearance of indolent/slow-progressing lymphoma, however it behaves like an agressive lymphoma. The treatment would be combinations of chemotherapies plus biological therapy. ...Read more

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How fast does squamous cell cancer spread to lymph nodes?

How fast does squamous cell cancer spread to lymph nodes?

Depends: There are several different types of squamos cell carcinomas, scc. For instance scc of the skin is not aggressive and very rarely spreads rapidly to lymph nodes. Scc of the lung is very aggressive and spreads rapidly. ...Read more

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What are helper T cells, killer T cells, and B cells?

What are helper T cells, killer T cells, and B cells?

Lymphocytes: Part of white blood cells, there are different types of lymphocytes, all look alike under the microscope, their functions differ, as their names imply, helper T cells orchestrate most of the immune system functions,killer T cells,are one of the first lines of body defence against invading microorganisms,and B cells' main function is to produce antibodies against microbes with the help of T cells ...Read more

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Does burkitt lymphoma fall under cancers?

Does burkitt lymphoma fall under cancers?

Taxonomy of: Malignancy used to derive from embyonal cells of origin. All ectoderm and endoderm linings were cancers, and tended to spread to nodes. All mesodermal origin tissues were sarcomas, and tended to bllod borne mets. Bone marrow and lymphatics were mesodermally derives, andformerly were called "lymphosarcoma". Frankly, historical interset only, not helpful. Burkitt is linked to ebstein barr virus. ...Read more

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Are lymphocyte rich hodgkin's lymphoma and nodular lymphocyte predominant hodgkin's lymphoma the same?

Sometimes: Both ate classified as hodgkin but they can behave differetlny. Both are treated te same with chemo abvd regimen. Some new data suggest adding Rituxan (rituximab) if cd 20 positive in lymphocyte predominantly disease. ...Read more

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What does "metastatic signet ring cell adenocarcinoma" mean?

What does "metastatic signet ring cell adenocarcinoma" mean?

Several things.: In this sentence metastatic most likely means the disease has spread to other organs such as liver, lung, etc. And would be considered stage 4; alternatively it could mean spread to lymph nodes only and would represent stage 3 disease. Signet ring is a description of what the cell looks like. Adenocarcinoma is the type of tumor and can arise from the GI tract, prostate, lung, breast or stomach. ...Read more

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Do follicular lymphoma cell divide? how does this disease progress if no transformation occurs?

Follicular lymphoma: is characterized by relatively slow cell proliferation, at least compared to other types of lymphoma. For this reason, it is classified as an "indolent" lymphoma. A characteristic gene mutation in follicular lymphoma involves a gene called BCL2, which results in reduced tumor cell death. The net result is a slow growing tumor that is easy to treat but hard to completely eradicate. ...Read more

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How do hodgkin lymphoma and non hodgkin lymphoma differ?

How do hodgkin lymphoma and non hodgkin lymphoma differ?

Spread pattern: Primarily, hodgkins lymphoma teens to spread from one lymph node site to an adjacent site. Non hodgkins lymphoma is more likely to skip lymph node chains to spread distantly. This is why local radiation has historically be more important in the treatment of hodgkins than non hodgkins. ...Read more

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How do a squamous cell and squamous cell carcinoma differ?

SCC: Squamous cells are normal epithelial cells present in a layer of the skin called the epidermis. When the architecture of the cell is distorted, severely disorganized, and has uninhibited growth, it becomes a cancer. ...Read more

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How many people have spindle cell neoplasm?

How many people have spindle cell neoplasm?

It is not rare: Spindle neoplasms are often labeled sarcomas which are an uncommon class of cancers, yet they make up about 10, 000 to 12, 000 cases in the us per year. ...Read more