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Doctor insights on: T Boz Sickle Cell Anemia

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How come clinical signs in sickle cell anemia don't appear until the child is a year old?

How come clinical signs in sickle cell anemia don't appear until the child is a year old?

Fetal hemoglobin: Sickle cell disease results from a mutation in the beta hemoglobin gene. In infants, the beta hemoglobin gene is largely not used by the body (the gene is "off"). Instead, babies use a different gene named gamma hemoglobin. The gamma hemoglobin does not carry the sickle mutation. During the 1st year of life, the body gradually switches from using gamma to beta. Thus, symptoms can be delayed. ...Read more

Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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Can you get sickle cell anemia as an adult, but didn't have it as a child or is it a hereditary?

Can you get sickle cell anemia as an adult, but didn't have it as a child or is it a hereditary?

Inherited: Sickle cell anemia is hereditary. But it comes in several varieties depending what was inherited from parents. S-s is severe & usually diagnosed in infancy. S-a is carrier state & may go undetected into adulthood. Many variants are possible. This refers to how hemoglobin proteins are manufactured by red cells programmed by genes. See: http://ghr.Nlm.Nih.Gov/condition/sickle-cell-disease. ...Read more

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I'm having a tough time with my sickle cell anemia. I'm hurting everyday. I don't know what to do.

I'm having a tough time with my sickle cell anemia. I'm hurting everyday. I don't know what to do.

Sickle cell anemia: What you need to do is see your hematology specialist as soon as you can. If you are not satisfied with this doctor ask your family or friends to tell you which other doctor they think is better. Please keep me informed. ...Read more

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How come clinical signs in sickle cell anemia don't appear until the child is at least 12 months old?

How come clinical signs in sickle cell anemia don't appear until the child is at least 12 months old?

Maturing hemoglobin: The hemoglobin involved with sickle cell develops after birth. Children are born with a different hemoglobin type and this changes over the first 3-6 months to be sickle hemoglobin. This is what delays the syptoms of sickle cell. ...Read more

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Is sickle cell anemia prevalent where malaria doesn't exist?

Only here in the US: If you compare a MAP of malaria prevalence (number of cases) to a MAP of sickle cell disease prevalence, they are almost super-imposable with one exception; the United States. The prevalence of sickle cell anemia in the us is as high as some african countries with lower malaria frequencies, but our only malaria comes from travelers. ...Read more

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If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more

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What is sickle cell anemia?

Hereditary: Sickle cell anemia is a hereditary condition where some of the red blood cells become sickle shaped and rigid, and can't get through the smallest capillaries. Blocked circulation causes extreme pain in joints, abdomen, or chest. ...Read more

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Is sickle cell anemia painful?

Is sickle cell anemia painful?

Pain crisis=painful: Sickle cell anemia itself is not painful . However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis ( this is painful), or other episode such as acute chest syndrome , stroke etc. ...Read more

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Can I have sickle cell anemia?

Can I have sickle cell anemia?

Anyone can...: It would be unlikely that would could reach the age of 46 and not be diagnosed with sickle cell anemia. If you are truly concerned, testing is very easy. ...Read more

Dr. Steven Ginsberg
1,236 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more