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Doctor insights on: T Boz Sickle Cell

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Dr. James Ball
355 doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more


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I have sickle cell anemia trait can that affect me?

I have sickle cell anemia trait can that affect me?

Usually not: Sickle cell trait is a hemoglobin genotype as and is generally regarded as a benign condition. However, individuals with sickle cell trait may have rare complications that mimic sickle cell disease. ...Read more

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Do beta thalassemia and sickle cell anemia always reduce life expectancy?

Do beta thalassemia and sickle cell anemia always reduce life expectancy?

Not if just 1 trait: Having either beta thalassemia trait or sickle cell trait is a mild condition and should not cause symptoms to the point of making a person frequently ill nor shortening life expectancy. Having beta thalassemia major or sickle cell disease, or both sickle cell trait and beta thalassemia trait, usually causes severe enough chronic disease symptoms to shorten lifespan an uncertain amount. ...Read more

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Can I have sickle cell anemia?

Can I have sickle cell anemia?

Anyone can...: It would be unlikely that would could reach the age of 46 and not be diagnosed with sickle cell anemia. If you are truly concerned, testing is very easy. ...Read more

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How do you test fetus for sickle cell anemia?

Genetic test Sickle: Yes the test is done on high risk women at the 17 week of gestation by doing amniocentesis with the permission of both patents. ...Read more

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How do people treat sickle cell anemia to prevent sickle cells?

How do people treat sickle cell anemia to prevent sickle cells?

Sickle cell Dz Rx: Several things may be helpful. Supportive measures include staying hydrated and eating a balanced diet. Some physicians recommend folate (folic acid) supplementation due to rapid rbc turnover. Antibiotic prophylaxis is recommended in children but can often be stopped in late childhood as instructed by your doctor. Regular care in a comprehensive center. Hydroxyurea can be beneficial by raising hgbf levels. ...Read more

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What make sickle cell patients lean?

What make sickle cell patients lean?

Not all patients....: With sickle cell disease are lean, but most are. There are several reasons, and many things we don't know. First, the half life of sickle red cells is much shorter than for normal rbcs. Thus pts must make red cells much more often, which requires energy. Also, caloric intake for sickle cell pts is less than required at quiescence and falls during crises and hospitalization. Many other factors 2. ...Read more

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Can we use hydroxyurea with sickle cell anemia patient?

Can we use hydroxyurea with sickle cell anemia patient?

HU in sickle cell: Certain patients with sickle cell can be helped by Hydroxyurea (hu). Initially, Hydroxyurea was thought to increase fetal hemoglobin levels (not carrying the sickle cell mutation), but more recently, hu has been shown to decrease high white blood cell counts which can lead to vaso-occlusive crises. Talk with your hematologist to see if hu is right for you. ...Read more

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Help docs, is hemoglobin AC a sickle cell trait?

Help docs, is hemoglobin AC a sickle cell trait?

No: Hgb AC is a heterozygous genetic state that is not sickle cell trait ( Hgb AS). Patient's with Hgb AC are clinically well with at worst mild asymptomatic anemia (most are not anemic). Individuals with Hgb AC can have children with Hgb SC (a type of severe sickle cell hemoglobinopathy) if their partner has either sickle cell trait (25% chance) or sickle cell disease (50% chance) ...Read more

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My baby have hb e/beta thalassemia? Is it sickle cell disease?

My baby have hb e/beta thalassemia? Is it sickle cell disease?

No: It is not sickle cell disease. It is a "hemoglobinopathy" or genetic disorder of hemoglobin...And it can cause anemia. Sickle cell has malformed red blood cells that become "sickle" shaped and can get stuck in organs and vessels and cause pain. E/beta thalassemia is different. ...Read more

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How did sickle cell anemia relate to malaria?

How did sickle cell anemia relate to malaria?

Malaria /sickle cell: In a person who has sickle-cell trait, the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity in areas with intense transmission of malaria.” S ...Read more

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What makes sickle cell anemia so significant?

Chronic disease: Sickle cell disease is so significant in that it is a chronic disease that affects almost every organ. Like diabetes, the effects of sickle cell, crises, and transfusions can permanently affect the heart, the kidneys, the liver, the lungs, and the brain. ...Read more

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If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?

Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait . With our technology now, nothing can alter the risk. Sorry to say , the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more

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What exactly does sickle cell trait do to me ? And if I have the sickle cell trait but I am anemia (anemic) what's the difference.

What exactly does sickle cell trait do to me ? And if I have the sickle cell trait but I am anemia (anemic) what's the difference.

Discuss With Doctor: Sickle Cell Trait (SCT); is genetic carrier state for Sickle Cell Disease. In SCT: 1 hemoglobin(Hg) is normal, other is sickle; anemia does not occur. However other abnormal Hg's exist & one can inherit sickle Hg from 1 parent with for example Thalassemia Hg from other parent. In this case mild anemia can occur with "SCT". People with SCT can have anemia not related to Hg too. Discuss with doctor. ...Read more

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Can you please tell me how sickle cell disase and sickle cell anemia differ?

Can you please tell me how sickle cell disase and sickle cell anemia differ?

It depends: This often gets confusing because doctors don't always use terms the same way. Sickle cell anemia typically refers to the condition where a person inherits two s genes; by convention hematologists call this ss. This is also a type of sickle cell disease, but often hematologist include other diseases like sc disease (one s gene, one c gene) or s/beta thal under the umbrella of sickle cell disease. ...Read more

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Are malaria and sickle cell anemia related? If so, how?

Are malaria and sickle cell anemia related? If so, how?

Yes: The mutation in sickle cell disease causes the red blood cell half-life to be shorter than normal. This can offer some protection against malaria because it disrupts the life cycle of the organism. This disease, along with thalassemias (which also shorten the red blood cell half-life), are prevalent in areas of the world that have high malaria rates. ...Read more

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How does exchange transfusion benefit sickle cell patients?

How does exchange transfusion benefit sickle cell patients?

Removes sickle cells: Acute red cell exchange is useful in acute infarctive stroke, in acute chest and multi-organ failure syndromes. The process replaces sickled red blood cells with normal red blood cells. This procedure can also benefit certain patients on chronic transfusion plans by replacing sickled cells without increasing the viscosity of blood. ...Read more

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What is sickle cell trait and anemia?

Genes: Sickle cell anemia occurs when someone has 2 sickle cell genes. Normal hemoglobin (hb) genes code for hb a. A sickle cell gene codes for hb s. Having 1 hb a gene & 1 hb s gene leads to sickle trait. This will have no symptoms, but has some health consequences. 2 genes for hb s leads to sickle cell anemia. To make things more complicated, there are other abnormal hb genes that can cause problems. ...Read more

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What are helper T cells, killer T cells, and B cells?

What are helper T cells, killer T cells, and B cells?

Lymphocytes: Part of white blood cells, there are different types of lymphocytes, all look alike under the microscope, their functions differ, as their names imply, helper T cells orchestrate most of the immune system functions,killer T cells,are one of the first lines of body defence against invading microorganisms,and B cells' main function is to produce antibodies against microbes with the help of T cells ...Read more