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Systemic Onset Juvenile Rheumatoid Arthritis
How does systemic juvenile rheumatoid arthritis affect someone during adulthood if it is different from rheumatoid arthritis?
How does systemic juvenile rheumatoid arthritis affect someone during adulthood if it is different from adult ra?
Autoinflammatory dis: Systemic jia/jra is actually an autoinflammatory disease rather than an autoimmune disease and is more similar to periodic fever syndromes than RA or jra. There's a problem with the innate immune system's triggering and control of inflammation, not a problem with mistakenly recognizing one's own proteins as foreign (like a virus). As such, Anakinra and steroids are most effective long term meds. ...Read moreSee 1 more doctor answer
Can systemic inflammatory response syndrome in a 5 year old with juvenile rheumatoid arthritis cause macrophage activation syndrome?
SIRS + JRA = MAS?: There is controversy as to whether macrophage activating syndrome is a real entity, versus it being confused for hemophagocytic lymphohistiocytosis (hlh). Hlh has much more defined criteria and can make a patient very sick (and requires chemo for treatment). A question i would have is could a patient with jra who develops sirs really have hlh. I would consult peds hem/onc (rheum mds may disagree). ...Read moreSee 2 more doctor answers
If with fever.: Some cases of jia (it is not RA in a child. We now call it juvenile idiopathic arthritis. In some with a variant called "still's disease, " hectic high fevers can occur. Vomiting is not uncommon with high fevers. Otherwise, if your child is not having fevers, it could be medication. Other issues are then probably present! ...Read moreSee 1 more doctor answer
Better control now: We have people in adulthood who have had jia also called juvenile idiopathic arthritis. It used to be called juvenile rheumatoid arthritis. We have much better ways to control the jia and our patients can have great control of their symptoms. We can use biologics which can help control a lot and some people can actually come completely off their medications and go into remission. ...Read more
No, not at all: There is no way to "outgrow" jra / jia. It can only be put into remission for periods of time from weeks to years, depending on what type of juvenile arthritis it is and how many joints were involved at the time of diagnosis. Kids with more active joints at diagnosis are more likely to flare more often when off meds. Until a cure is found, we work for remission with minimal flares of diease. ...Read moreSee 2 more doctor answers
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