Doctor insights on:
Systemic Onset Juvenile Rheumatoid Arthritis
Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
How does systemic juvenile rheumatoid arthritis affect someone during adulthood if it is different from rheumatoid arthritis?
How does systemic juvenile rheumatoid arthritis affect someone during adulthood if it is different from adult ra?
Autoinflammatory dis: Systemic jia/jra is actually an autoinflammatory disease rather than an autoimmune disease and is more similar to periodic fever syndromes than RA or jra. There's a problem with the innate immune system's triggering and control of inflammation, not a problem with mistakenly recognizing one's own proteins as foreign (like a virus). As such, Anakinra and steroids are most effective long term meds. ...Read moreSee 1 more doctor answer
If with fever.: Some cases of jia (it is not RA in a child. We now call it juvenile idiopathic arthritis. In some with a variant called "still's disease, " hectic high fevers can occur. Vomiting is not uncommon with high fevers. Otherwise, if your child is not having fevers, it could be medication. Other issues are then probably present! ...Read moreSee 1 more doctor answer
Can systemic inflammatory response syndrome in a 5 year old with juvenile rheumatoid arthritis cause macrophage activation syndrome?
SIRS + JRA = MAS?: There is controversy as to whether macrophage activating syndrome is a real entity, versus it being confused for hemophagocytic lymphohistiocytosis (hlh). Hlh has much more defined criteria and can make a patient very sick (and requires chemo for treatment). A question i would have is could a patient with jra who develops sirs really have hlh. I would consult peds hem/onc (rheum mds may disagree). ...Read moreSee 2 more doctor answers
Immune dysfunction!: Jra (also called jia) for juvenille idiopathic arthritis is a disease of unknown etiology. There are many theories for why it happens, many believe there is a virus responsible. The damage to the joints, pain and stiffness is due to an inappropriate immune response which results in the immune system attacking tissues of the host (patient). Rheumatologists can provide appropriate DX and rx. ...Read moreSee 2 more doctor answers
Autoimmune: Juvenile rheumatoid arthritis occurs when the immune system gets confused and starts attacking the joints instead of fighting intruders like bacteria and viruses. Genetic factors play a role in risk for developing autoimmune diseases. Exposure to certain viruses may play a role as well. ...Read moreSee 1 more doctor answer
- Talk to a doctor live online for free
- Does systemic juvenile rheumatoid arthritis sometimes cause you to vomit?
- Juvenile rheumatoid arthritis stress
- Juvenile rheumatoid arthritis pregnancy
- Ask a doctor a question free online
- Juvenile rheumatoid arthritis and minocin
- Juvenile rheumatoid arthritis rain
- Juvenile rheumatoid arthritis tylenol
- Juvenile rheumatoid arthritis in adults
- Talk to a pediatrician online