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Doctor insights on: Systemic Lupus Erythematosus Sle Comprehensive Diagnostic Panel

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Systemic lupus erythematosus--what is sle?

Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more


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Is lupus erythematosus infectious?

No: Is a immune based disease does not recognize self and attacks multiple organs. ...Read more

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What are the tests for systemic lupus erythematosus?

What are the tests for systemic lupus erythematosus?

Positive ANA and...: Positive ANA and a positive double stranded dna antibody titer of significance. This coupled with clinical criteria is the least required for diagnosis. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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Dr. Alfred Kim Dr. Kim
2 doctors agreed:
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What gene causes lupus erythematosus?

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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What is treatment for systemic lupus erythematosus?

What is treatment for systemic lupus erythematosus?

S L E : Systemic lupus erythematosus is an auto immune disease, that can affect skin, joints, kodneys, brain, and other organs.Auto immune means bodys immune system mistakenly attacks healthy tissues it is treated with steroids and non steroidal anti inflammatory meds, avoid sun and wear protective clothing. Cytotoxic drugs if you do not respond to cortico steroids cytotoxics have side effects need to be monit. ...Read more

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Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.

Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read more

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What are some alternative therapies for sle (systemic lupus erythematosus)?

What are some alternative therapies for sle (systemic lupus erythematosus)?

None: Diet and omega 3 fatty acids may help but there are no specific vitamin or herbal supplements for sle. Avoiding sugar and dairy is helpful for some people. Omega three fatty acids along with vitamin c and b complex may reduce symptoms. ...Read more

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Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd lupus.Possible w/normal labs?

Lupus: Seems consistent with SLE . Need Rheumatologist follow up and specific anti double stranded DNA and other labs. SLE affects your kidney and can cause pericarditis. Immediate follow and management is helpful. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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DLE confirmed by ANA test and CBC at Dermatology symptoms 2013 Biopsy now cancelled. Only criteria to SLE Discoid Rash Photosensivity.SLE?

DLE confirmed by ANA test and CBC at Dermatology 
symptoms 2013 Biopsy now cancelled. Only criteria to SLE Discoid Rash Photosensivity.SLE?

Discoid lupus: Dx is confirmed by biopsy. Also review medications r ,as some medications can cause a lupus like syndrome. Lupus has multiple criteria and there is usually a battery of antibody tests done., tests may initially be negative and later turn positive. f/u w/ rheumatology for second opinion http://www.dermnetnz.org/topics/drug-induced-lupus-erythematosus/ ...Read more

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RA factor,ANA positive with polyarthritis ACCP negative and polyclonal hypergammaglobulinaemia. whats the diagnosis?

Auto immune disorder: The information you provided is not sufficient to provide a specific diagnosis. It suggest an auto-immune inflammatory disorder. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

Dr. Steven Griggs
3 doctors shared insights

Lupus (Systemic Lupus Erythematosus) (Definition)

An inflammatory disease caused by the immune system attacking one's own tissues throughout the body. ...Read more