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Doctor insights on: Systemic Lupus Erythematosus Sle Antinuclear Antibodies Present

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Why do symptoms often show up yrs before labs (specific antinuclear antibodies, etc) in a diagnosis of lupus? I'm near diagnosis with only high +ana. What causes the sx?

Why do symptoms often show up yrs before labs (specific antinuclear antibodies, etc) in a diagnosis of lupus? I'm near diagnosis with only high +ana.  What causes the sx?

Lupus is a mystery: Lupus is a famous master of masquerade--it can mimmic many disease states. Lupus symptoms may be present much earlier than when it can be diagnosed, thus lab measurement only provide a guide. This only means the lab has its limitation and medical science has only gotten this far. Don't rely on the lab, but rather rely on your bopdy--maybe something else is going on. Consult your doc. Good luck. ...Read more

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Is there a cure for systemic lupus erythematosus (sle)?

Is there a cure for systemic lupus erythematosus (sle)?

SLE treatment: Systemic lupus erythematosus (sle) is a long-term autoimmune disorder that may affect the skin, joints, kidneys, brain, and other organs. There is no cure for sle. The goal of treatment is to control symptoms. ...Read more

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What are some alternative therapies for sle (systemic lupus erythematosus)?

What are some alternative therapies for sle (systemic lupus erythematosus)?

None: Diet and omega 3 fatty acids may help but there are no specific vitamin or herbal supplements for sle. Avoiding sugar and dairy is helpful for some people. Omega three fatty acids along with vitamin c and b complex may reduce symptoms. ...Read more

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Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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What are the risks of getting your wisdom teeth extracted with systemic lupus erythematosus?

What are the risks of getting your wisdom teeth extracted with systemic lupus erythematosus?

Depends: If you have been on steroids recently for flare ups of sle, it could lead to post operative complications. Also, there is always a chance that there may be a latent cardiac problem that will only become apparent when you are under stress, like during a surgery. I would see and oral surgeon, and have him/her work with your physician to manage your case safely. ...Read more

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How much should people with systemic lupus erythematosus pay extra for the insurance in usa?

None: The reason that insurance exists is to spread the risk of any single person having any disease is divided among many healthy people with no disease.Our current system is prejudiced against anybody with a "pre-existing" illness such as yours and makes you pay extra.Makes getting insurance(or keeping it ) tough.It is a lose-lose;dr and patient, win for insurance company.My gripe with aca. ...Read more

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Can active systemic lupus erythematosus be caused by prescription medication? Need expert opinions!

Drug-induced lupus: Yes, some prescription medications can definitely cause drug-induced lupus which often will resolve after the drug is stopped. Many of the drugs that can cause lupus do NOT cause lupus in the majority of people treated with them. There may be genetic susceptibility to drug-induced lupus and/or the right trigger. Many possible meds. Best way is to be evaluated by a board certified rheumatologist ...Read more

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Is the cognitive dysfunction that results from systemic lupus erythematosus typically permanent?

It depends: Lupus can cause both reversible and irreversible changes to the nervous system, and these can affect personality, memory, and other basic aspects of patients' lives. That said, simply being sick can aggravate depression, sleep deprivation, etc. Controlling pain and other disruptive elements of the disease, can improve quality of life and help people be more who they would like to be. ...Read more

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What can I use for systemic lupus erythematosus symptoms if I don't have a new doctor yet?

Many but need doctor: The first thing to do is define your lupus, everyone with lupus is different.You need to contact your physician - see a rheumatologist, define your lupus and then you decide on your treatment. Not everyone with lupus needs meds, but you need good health habits - no smoking, exercise, etc defining your type of lupus will clarify the best medications for you to take. ...Read more

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Prednisone is most likely to be indicated in the management of systemic lupus erythematosus due to what?

Prednisone is most likely to be indicated in the management of systemic lupus erythematosus due to what?

Antiinflammatory: Prednisone suppresses inflammation and thus it is intended to control the inflammation resulting from many diseases including lupus and rheumatoid arthritis. It is not a cure or specific for any disease , just a temporary solution. Long term high-dose prednisone can lead to many serious side effects. ...Read more

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Can systemic lupus erythematosus cause swelling in one hand?

Can systemic lupus erythematosus cause swelling in one hand?

Yes: A common symptom of sle is arthritis or joint pain and swelling which can involve just one hand. Usually there will be other symptoms as well such malar rash (red rash over the cheeks), increased sensitivity to sun, possibly hair loss and rash on the body, hands or knuckles or scalp. ...Read more

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What is the definition or description of: systemic lupus erythematosus diagnostic panel?

Labs for a + ANA: The antinuclear antibody test (ANA) is the initial screening test for lupus, but since it produces a lot of false positives, follow up testing for other auto antibodies is needed. The other tests in the panel are usually more specific for lupus, but less sensitive. Panels sometimes produce dubious results, so any positive test has to be taken in context. ...Read more

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Docs can you explain what is 'systemic lupus erythematosus' in clear details?

An auto immune disea: Systemic lupus is a auto immune disease that can affect any part of the body.The immune system of the patient attacks its own body cells and tissues, and that causes inflammation and damage to the tissues it most often affecrs heart, skin.Joints, blood vessels, lungs, kidneys , liver and nervous system the incidence of sle is 9 times in women than men. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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How can one cure systemic lupus erythematosus?

How can one cure systemic lupus erythematosus?

No cure but ...: Lupus cannot be cured but the symptoms can often be controlled. In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Lupus can be mild. Many lupus patients have non-life threatening disease. Lupus can be severe. Kidney or brain involvement portends a worse prognosis. ...Read more

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What are the tests for systemic lupus erythematosus?

What are the tests for systemic lupus erythematosus?

Positive ANA and...: Positive ANA and a positive double stranded dna antibody titer of significance. This coupled with clinical criteria is the least required for diagnosis. ...Read more

Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more


Dr. Alfred Kim
25 doctors shared insights

Antinuclear Antibodies (Definition)

Antinuclear antibodies present - about half of those who have this have an auto-immune disease. ...Read more