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Doctor insights on: Systemic Lupus Erythematosus

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Systemic lupus erythematosus--what is sle?

Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more


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What are the symptoms of systemic lupus erythematosus?

What are the symptoms of systemic lupus erythematosus?

Many: People with lupus may have joint pain, skin rashes, chest pain, heart probelms, hair loss, fingers changing color in the cold, rash in the sunshine, neuro-psychologic problems. These are only soemof the symtpoms peopel can have. They can also have none of these. Your physician will evaluate all of these, get labs tests and imaging. ...Read more

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What are the tests for systemic lupus erythematosus?

What are the tests for systemic lupus erythematosus?

Positive ANA and...: Positive ANA and a positive double stranded dna antibody titer of significance. This coupled with clinical criteria is the least required for diagnosis. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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What is treatment for systemic lupus erythematosus?

What is treatment for systemic lupus erythematosus?

S L E: Systemic lupus erythematosus is an auto immune disease, that can affect skin, joints, kodneys, brain, and other organs. Auto immune means bodys immune system mistakenly attacks healthy tissues

it is treated with steroids and non steroidal anti inflammatory meds, avoid sun and wear protective clothing. Cytotoxic drugs if you do not respond to cortico steroids
cytotoxics have side effects need to be monit. ...Read more

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How can one cure systemic lupus erythematosus?

How can one cure systemic lupus erythematosus?

No cure but. ..: Lupus cannot be cured but the symptoms can often be controlled. In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Lupus can be mild. Many lupus patients have non-life threatening disease. Lupus can be severe. Kidney or brain involvement portends a worse prognosis. ...Read more

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How can one cure systemic lupus erythematosus?

No cure but. ..: Lupus cannot be cured but the symptoms can often be controlled. In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Lupus can be mild. Many lupus patients have non-life threatening disease. Lupus can be severe. Kidney or brain involvement portends a worse prognosis. ...Read more

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What are the tests for systemic lupus erythematosus?

Positive ANA and...: Positive ANA and a positive double stranded dna antibody titer of significance. This coupled with clinical criteria is the least required for diagnosis. ...Read more

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What is 'systemic lupus erythematosus' in clear tems?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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What are the symptoms of systemic lupus erythematosus?

Many: People with lupus may have joint pain, skin rashes, chest pain, heart probelms, hair loss, fingers changing color in the cold, rash in the sunshine, neuro-psychologic problems. These are only soemof the symtpoms peopel can have. They can also have none of these. Your physician will evaluate all of these, get labs tests and imaging. ...Read more

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What do you recommend for systemic lupus erythematosus?

See rheumatologist: It is critical to see a rheumatologist, who can determine if it is lupus, if it actually compromises your health, what body systems are affected and if treatment is needed, to tailor the treatment to the risks they present. ...Read more

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What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

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What is the definition or description of: systemic lupus erythematosus?

SLE: Lupus erythematosus is a name given to a collection of autoimmune diseases, in which the human immune system becomes hyperactive and attacks normal, healthy tissues. Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. ...Read more

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What is the definition or description of: systemic lupus erythematosus diagnostic panel?

Labs for a + ANA: The antinuclear antibody test (ANA) is the initial screening test for lupus, but since it produces a lot of false positives, follow up testing for other auto antibodies is needed. The other tests in the panel are usually more specific for lupus, but less sensitive. Panels sometimes produce dubious results, so any positive test has to be taken in context. ...Read more

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How much should people with systemic lupus erythematosus pay extra for the insurance in usa?

None: The reason that insurance exists is to spread the risk of any single person having any disease is divided among many healthy people with no disease. Our current system is prejudiced against anybody with a "pre-existing" illness such as yours and makes you pay extra. Makes getting insurance (or keeping it) tough. It is a lose-lose;dr and patient, win for insurance company. My gripe with aca. ...Read more

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Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

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Docs can you explain what is 'systemic lupus erythematosus' in clear details?

Docs can you explain what is 'systemic lupus erythematosus' in clear details?

An auto immune disea: Systemic lupus is a auto immune disease that can affect any part of the body. The immune system of the patient attacks its own body cells and tissues, and that causes inflammation and damage to the tissues
it most often affecrs heart, skin. Joints, blood vessels, lungs, kidneys, liver and nervous system
the incidence of sle is 9 times in women than men. ...Read more

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Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

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Is systemic lupus erythematosus a kind of cancer?

Is systemic lupus erythematosus a kind of cancer?

No: It is an autoimmune disorder that can affect multiple organs. It is not cancer. ...Read more

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How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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Can active systemic lupus erythematosus be caused by prescription medication? Need expert opinions!

Drug-induced lupus: Yes, some prescription medications can definitely cause drug-induced lupus which often will resolve after the drug is stopped. Many of the drugs that can cause lupus do NOT cause lupus in the majority of people treated with them. There may be genetic susceptibility to drug-induced lupus and/or the right trigger. Many possible meds. Best way is to be evaluated by a board certified rheumatologist ...Read more

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Is there a cure for systemic lupus erythematosus (sle)?

SLE treatment: Systemic lupus erythematosus (sle) is a long-term autoimmune disorder that may affect the skin, joints, kidneys, brain, and other organs. There is no cure for sle. The goal of treatment is to control symptoms. ...Read more

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Why is the butterfly rash in systemic lupus erythematosus?

Why is the butterfly rash in systemic lupus erythematosus?

Thin skin: Thin area around the nose/cheeks is very sensitive to sun and the first to show sle signs. ...Read more

Dr. Jan Lei Iwata
3 Doctors shared insights

Lupus (Systemic Lupus Erythematosus) (Definition)

An inflammatory disease caused when the immune system attacks its own tissues. ...Read more