Doctor insights on:
Systemic Inflammatory Response
Inflammation bad!: Inflammation dose many things deleterious to the body including: releases inflammatory cytokines into the blood stream. This damages your blood vessels and accelerates atherosclerosis. Clotting factors rise, which are thrombotic themselves. The body enters a catabolic state (tiisue breakdown). People feel fatigued and bad. Inflammation from any cause need to treated. ...Read more
The conference concluded that the manifestations of sirs include, but are not limited to:
body temperature less than 36°c (96.8°f) or greater than 38°c (100.4°f)
heart rate greater than 90 beats per minute
tachypnea (high respiratory rate), with than 20 breaths per minute; or, an arterial partial pressure of carbon dioxide less than 4.3 kpa (32 mmhg)
white blood cell count less than 4000 cells/mm³. ...Read more
Can be: Systemic Inflammatory Response Syndrome which is either fever or hypothermia, either high or low blood count with many WBC band forms, tachycardia and tachypnea, can be seen in infections with sepsis and in noninfectious insults such as trauma or burns. Therefore depending on the cause it can be associated with pain. ...Read more
Can SIRS (systemic inflammatory response syndrome) be an underlying cause of delirium or be otherwise associated with delirium?
Delirium: In critically ill patients, delirium is a frequent occurrence. Investigators have found that the profile of increased inflammatory biomarkers changes in critically ill patients with delirium according to the presence or absence of clinical evidence of inflammation (either infection or systemic inflammatory response syndrome). Thus, there is a reasonable associate between the two. ...Read more
I have vomiting episodes that lead to systemic inflammatory response syndrome without sepsis. What causes sirs? Insufficient cortisol from adrenals?
Multifactorial: As a general rule, inflammatory conditions which produce the criteria necessary to term a condition sirs are induced by cytokine release, but there are many other possibilities. Generally not adrenal insufficiency. You seem to be trying to acquire a shorthand medical education. It is not that simple. ...Read more
Yes: Sirs represents an inflammatory response that has 'gone out of control, ' and is defined usually by vital signs abnorms and abn's in the blood count. Can occur with autoimmune problems, pancreatitis, burns, other physiological insults. If an infection is detected (with cultures, or clinically), then we refer to it as sepsis. Docs will sometimes use terms loosely, leading to some confusion. ...Read more
Definition: "systemic inflammation" is a generic term of inflammation in the body. The systemic inflammatory response syndrome, or sirs, is a particular reaction of the body after an infection (which is called sepsis) or trauma or other injury. The specific components of sirs are available to review online (simply "google" sirs). So, it's sort of similar but not exactly. Hope this helps! ...Read more
SIRS: Sirs may result from a myriad of underlying causes. Treating the cause and supportive measures are the mainstay of the treatment. ...Read more
Can systemic inflammatory response syndrome in a 5 year old with juvenile rheumatoid arthritis cause macrophage activation syndrome?
SIRS + JRA = MAS?: There is controversy as to whether macrophage activating syndrome is a real entity, versus it being confused for hemophagocytic lymphohistiocytosis (hlh). Hlh has much more defined criteria and can make a patient very sick (and requires chemo for treatment). A question I would have is could a patient with jra who develops sirs really have hlh. I would consult peds hem/onc (rheum mds may disagree). ...Read more
Cardiologists treat cardiac conditions & pulmonologists treat lung diseases. What is the name of the type of specialist who treats sirs (systemic inflammatory response syndrome)?
Intensivist: Typically an intensivist or an id specialist. ...Read more
Inflammation: Ask Dr. Wikipeida. Great description.Get a more detailed answer ›
Several: The more "generic" tests to mesure inflammation are effected by many things. Some of the tests that doctors use for this include: ESR "sed rate"; CRP (c-reactive protein). Both of these can be false effected by various reasons, but all of them also give you an idea of inflammation. None of these tests specifically test the function of the immune system, or screen for immune deficiency. ...Read more
Inflammation: The body's natural healing process requires several steps including substances within the blood that help with primary healing. After any injury, the capillaries become "leaky" and hence the swelling. Sometimes it causes additional issues like compression of the surrounding structures and has to be curtailed by anti-inflammatory meds which may also help with the pain due to the swelling. ...Read more
Usually there is not:
Much of an inflammatory response to a stroke. Ask your neurologist.
They will help you. ...Read more
When you get a virus is it the the virus itself that makes u sick? Or yur body's inflammatory response and histamine release to the virus that does?
Can you tell me if throughout the local inflammatory response, a lack of mast cells would result in?
Mast cells: The IgE-primed mast cell releases granules and powerful chemical mediators, such as histamine, cytokines, granulocyte macrophage colony-stimulating factor (GM-CSF), leukotrienes, heparin, and many proteases into the environment. These chemical mediators cause the characteristic symptoms of allergy. ...Read more
Almost every scratch my 8 year old gets becomes infected. Is there something we should investigate? My GP says it's a normal inflammatory response.
Points to consider: You can have a puss swab done to culture which bacteria if any is responsible for this. Often it is Staph aureus. Then treated with tested sensitive antibiotics. He might also be carrying the germ. Often fingernails and nose. Ask your doc about preventing carrier and treatment. Have his glucose and blood count checked. ...Read more
I do believe the allergy shots indirectly are causing an inflammatory response in my body along with antihistamines adding to it. What can I do? I'm about to stop the shots. I do not want to gain anymore weight.
I have costochrondritis. Does Omega-3 oil truly help lower the body's inflammatory response or is it a myth. If not, how much should I take daily?
Omega 3: Some studies claim an effect. In one study patients with back pain took a preparation and it seemed to help reduce needs for NSAIDs, but that was in that study. Any new medication and dose should be discussed with your PCP. But in that study they took 1200 mg, but the exact brand/? I don't know. Many result are VERY dependent upon which one you take. Http://www. Ncbi. Nlm. Nih. Gov/pubmed/165 ...Read more
I have fm and a systemic inflammatory autoimm. Disease that affects my joints skin and hair, is there a more exact diagnosis for my autoimm. Disease?
Sometimes not: Please see your dermatologist for evaluation and to discuss treatment options. This way you can find out. ...Read more
Sed Rate and: C-reactive protein come to mind. Non-specific, commonly indicate body reaction to infection, and sometimes tiumors especially lymphoma. These measure proteins and those in the gamma globulin class that may respond to antigen. Inflammatory cytokines can go up in response to treatment and healing as well. ...Read more
Mixed bag: Some elements of butter can be anti-inflammatory. Most of what's referred to healthy wise in butter are that it contains butyric acid which appears to have anti-inflammatory properties along with, but to a lesser extent, conjugated linoleic acids. But be careful what you wish for, too much of anything can damaging, particularly as butter is so calorically dense. ...Read more