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Doctor insights on: Systemic Hives

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22yr female. Experience the following symptoms: angioedema, chronic urticaria, anaphylaxis, bone/muscle pain etc, is this systemic mastocytosis?

22yr female. Experience the following symptoms: angioedema, chronic urticaria, anaphylaxis, bone/muscle pain etc, is this systemic mastocytosis?

Serum tryptase level: You're certainly describing an entity that sounds histamine mediated but of course can be due to other causes and mediators.
Does she have urticaria pigmentosa?
Have you done a serum tryptase level?
To my knowledge the one definitive diagnostic is a bone marrow bx.
The other lab I look at to asses a histamine mediated process is anti high affinityfc epsilon receptor antibodies.
Any meds? ...Read more

Dr. Mark Ingerman
3 Doctors shared insights

Hives (Definition)

An outbreak of red bumps or wheals that appear quickly after exposure to certain allergens (foods, medications, other substances). They can vary in size, are itchy, can burn, and can last for up to ...Read more


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What are hives?

What are hives?

Itchy, red, raised.: Hives are itchy, red, raised lesions on the skin and they usually happen after contact with or ingestion of something you're allergic to. Try some benadryl, (diphenhydramine) cold packs, and see your doctor if they get worse! ...Read more

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What are hives?

Skin rash: That is characteristically raised, evanscent, and itchy. ...Read more

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What causes hives?

What causes hives?

Many causes: There are many causes of hives and these include infections, medications, bee/wasp stings, food allergies, environmental allergies, stress, cold temperatures, and exercise amongst other rarer causes. Oftentimes, hives are idiopathic, meaning there is no known cause.

For further evaluation and management, consultation with a board-certified allergist is recommended for evaluation and management. ...Read more

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What causes hives?

Usually allergic rxn: Usually it is caused by an allergic reaction, like contacting something you're allergic to touch. Consult your physician. Wishing you the best. ...Read more

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Are hives chronic?

Are hives chronic?

Depends: Hives can be acute and last less than 1 day- 1 week or they can be chronic lasting greater than 6 weeks. Acute hives often have a trigger- such as food, medication, bug bite, venom sting, or pet allergy. However, they can also coincide with infections and the cause may not be easy to identify. Hives that are chronic >6 weeks require evaluation by an allergist and often have no known cause. ...Read more

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How to trat hives?

How to trat hives?

Avoid and take meds: Hives are generally treated by removing the offending trigger and taking antihistamines (loratadine, Cetirizine or fexofenadine) or glucocorticoids if lesions are severe. ...Read more

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What causes hives?

Anything: Just about anything and everything can cause hives. Despite this we never determine the cause in many cases of chronic hives. Treatment is the main approach. For many people the hives eventually go away. ...Read more

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Is hives permanent?

Well....: I think you mean to say will you keep getting hives "forever"? If you are clearly get hives when you come into contact some "offending agent" then every time you come into contact with it yes, you will get hives, and maybe worse. However, a lot of the time we are not able to determine why you get hives (or to what). See your dermatologist or allergist if it continues to be a problem. ...Read more

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What can cause hives?

What can cause hives?

So Many Causes: There are a number of potential causes of hives (urticaria) which include: viral infections, parasitic infections, IgE-mediated allergic reactions like bee stings, medication allergy, latex allergy, food allergy, transfusion reactions, and contact reactions. Some meds/products can induce hives like narcotics, radiocontrast media, muscle relaxants, stinging nettle, physical stimuli, and foods. ...Read more

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Can drugs cause hives?

Yes: Any drug can cause hives. Some drugs may take minutes, others a few hours. ...Read more

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Are my hives permanent?

No.: Hives can be chronic which means that they have lasted for more than 6 weeks. They may last for several months, but almost always resolve eventually. However, they may return at a later time. ...Read more

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How long do hives last?

How long do hives last?

Varies: Sometimes hours....Sometimes months. It varies depending on the cause. ...Read more

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Why am I getting hives?

Why am I getting hives?

Hives: Http://www. Webmd. Com/skin-problems-and-treatments/guide/hives-urticaria-angioedema#1

Get a more detailed answer ›
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What could cause hives?

What could cause hives?

Many things: Would see an allergist who can best determine the cause if one is obvious. In most cases a cause is never found. ...Read more

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How fast can hives spread?

Very rapidlly: Some allergic reactions are more aggressive than others and spread rapidly. In this case the patient needs emergency medical evaluation. ...Read more

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Why don't some hives itch?

Why don't some hives itch?

Are you sure?: Do you really have hives since nearly all hives itch. A bump on the skin is not necessarily a hive. ...Read more

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How should I control hives?

How should I control hives?

Find trigger first: If a trigger for the hives is found, this should be avoided. If no obvious trigger, antihistamines such as claritin, (loratadine) allegra, zyrtec are indicated for treatment of hives. An allergist can assist in finding the trigger and developing a treatment plan for the hives. Sometimes different doses of antihistamines are used or combinations with other medications are used to obtain control. ...Read more

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What can I do about hives?

Don't worry!: Hive are uncomfortable, but not dangerous or contagious. For acute hives, the cause is frequently found and easily treated with antihistamines and avoiding the trigger. For chronic hives (>6 weeks), an allergist can assist in finding the trigger and a treatment plan that does not include steroids. Don't panic...Anxiety may aggravate hives. ...Read more

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Hives from taking singular?

Uncommon: Singulair (montelukast) is often given to treat allergic conditions and allergic people develop hives. However, although it is possible for singulair (montelukast) to cause hives, it is not common. ...Read more

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Wat is the sythoms of hives?

Itching: Itchy welts of varying sides would be the most common manifestation for h ives. ...Read more

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What are the causes of hives?

What are the causes of hives?

Many causes: Hives can be due to many things including:
1. Allergies to pollens, mold, dust, food, drugs and bee stings
2. Infections like hepatitis
3. Autoimmunity
4. Complement deficiency – acquired or hereditary
5. Vaculitis
6. Idiopathic – unknown cause – very common
treatment may include antihistamines, steroids, h2 blockers and if very severe, cyclosporine. ...Read more

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How exactly do you get hives?

How exactly do you get hives?

An allergic reaction: Hives occur when mast cells release histamine. Histamine makes nearby nerve endings fire causing the sensation of itching & iincreasing blood flow causing redness. Small veins leak plasma (the liquid part of blood) causing local edema - that's the white bump. Hives lasting 6 weeks or less are usually caused by a virus or an allergic reaction to a food, medication, insect bite or sting. ...Read more

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Can I die from getting hives?

Very rare: It is rare for idiopathic hives (spontaneous hives without an obvious cause) to be deadly. Some people may get swelling of the lips or tongue, but it only rarely affects the breathing. If it does, Epinephrine can be lifesaving. Allergic reactions (to food, insect stings, medications, etc.) can cause hives and can be deadly. Again, Epinephrine is the treatment. See an allergist for more info. ...Read more

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What is the mediine for hives?

What is the mediine for hives?

Antihistamines: Hives can be treated with otc antihistamines like benadryl, (diphenhydramine) zyrtec. They tend to resolve once the trigger has abated. Anything prolonged >3 days must be examined by a medical professional. ...Read more

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How come I keep getting hives?

Do not know: Recurrent urticaria warrants medical evaluation. I would start with your family doctor. However may need to be seen by an allergist. ...Read more

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What are the symptoms of hives?

What are the symptoms of hives?

Itching and rash: Hives are a red raised rash often described as welts. Itching is often very intense. Hives are usually warm to the touch and feel "puffy". ...Read more

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How do I get relief from hives?

Avoid: Avoid the causative agent. Use an over the counter antihistamine such as Cetirizine in adequate dose. Cool compresses, avoidance of heat and irritants. Consider additional agents if these don't work. See your doc. ...Read more

Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more